Immunization sheep

Sheep anti-rabbit gammaglobulins for separation step An antibody to rabbit y-globuhns was raised by immunizing sheep with rabbit y-globulins. 

Seveso, Italy, caused wide-spread pollution of the industrial site as well as its surroundings. Serious effects of dioxin were detected both in dontestic animals, such as cows and sheep, and in humans, the most serious early effects being a serious skin disease, chloracne, and alterations in the function of the immune system. Follow-up studies have demonstrated that this accident also increased the cancer risk in exposed individuals. ... 

Rat DBTC 4-6 weeks at 0, 50, and 150 mg/kg diet = 0, 2.5, and 7.5 mg/kg body weight Decrease in ceiiuiar and humorai immune response, in haemaggiutination and haemoiysin titres suppression of primary antibody response against sheep red biood ceiis Lowest dose at which effects were reported = 2.5 Seinen et al. (1977b)... 

Andrews, S.J., Hole, N.J.K., Munn, E.A. and Rolph, T.P. (1995) Vaccination of sheep against haemonchosis with Hll - prevention of the periparturient rise and colostral transfer of protective immunity. InternationalJournal for Parasitology 25, 839-846. 

Karanu, F.N., McGuire, T.C., Davis, W.C., Besser, T.E. and Jasmer, D.P. (1997a) CD4+T lymphocytes contribute to protective immunity induced in sheep and goats by Haemonchus contortus gut antigens. Parasite Immunology 19, 435—145. 

Piacenza L., Acosta, D., Basmadjan, I., Dalton, J.P. and Carmona, C. (1999) Vaccination with cathepsin L proteases and with leucine aminopeptidase induces high levels of protection against fascioliasis in sheep. Infection and Immunity 67, 1954-1961. 

The few homeopathic products which were tested against GIN in sheep and cattle were based on plants and were not associated with a decrease in the worm burdens or faecal egg counts. However, considering the basic principles of homeopathy, it is likely that this approach reacts via modulation of the host s immune system (Cabaret et al., 2002). The use of non-classical parameters for assessing an antiparasitic effect should therefore be considered in future studies of homeopathy. 

Gruner, L., Cortet, J., Sauve, C., Limouzin, C. and Brunei, J. C. (2002). Evolution of nematode immunity in grazing sheep selected for resistance and susceptibility to Teladorsagia circumcincta and Trichostrongylus colubriformis a 4-year experiment . Veterinary Parasitology, 109, 277-291. 

These specific substances or blood group factors are detected by their property of inhibiting agglutinin reactions between human erythrocytes and heterologous human sera. This is the so-called isoagglutinin test which can detect the factors in dilutions of more than 1 part in 10 million. An even more sensitive but less specific test is their power to inhibit hemolysis of sheep s erythrocytes by the serum of rabbits immunized with certain human corpuscles. 

A number of animal diseases caused by viruses involve primary demyelination and often are associated with inflammation. These diseases are studied as animal models, which may provide clues about how a viral infection could lead to immune-mediated demyelination in humans [1, 5, 6]. Canine distemper virus causes a demyelinating disease, and the lesions in dog brain show a strong inflammatory response with some similarities to acute disseminated encephalomyelitis in man [ 1 ]. Visna is a slowly progressive demyelinating disease of sheep caused by a retrovirus [ 1 ]. 

In rodents, sheep red blood cells (SRBC) are routinely used for immunization. The antibody response is determined using the plaque forming cells assay (PFC) or by plasma SRBC-specific antibody titer [21, 22], As an alternative to SRBC, other T-cell-dependent antigen may be used, including keyhole limpet hemocyanin (KLH), tetanus toxoid (TT), or pneumococcal antigen. 

Humoral-mediated immunity LPS (lipopolysaccharide) mitogen response or F(ab)2 mitogenic response enumeration of plaques by IgM antibody-forming cells to a T-dependent antigen (sheep red blood cells serum IgM concentration... 

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