Hydroxy-methyl-cellulose

If the drug is insoluble in water, suspensions have to be administered. In such cases vehicles like sesame oil, hydroxy-methyl-cellulose or hydroxy-ethyl-cellulose can be used. The selection of the vehicle is a critical issue because of inherent toxicity of the vehicle used frequently for kinetic and metabolism studies (e.g. vehicles which form metabolically oxalic acid). Natural oils such as sesame or com oil can be used. However, it should be checked whether the use of oily vehicles alters the gastrointestinal absorption due to their laxative properties and whether oily vehicles can cause oil granulomas (reaction to oily vehicles in the reticulo-endothelial system) in case of parenteral administration. 

To bum out forming/processing (e.g., extrasion) enablers (e.g.. Hydroxy Methyl Cellulose, Sodium stearate, etc.), and pore formers (e.g., starch, graphite, etc.) This can he achieved at temperatures below 800 - 1000°C. 

A majority of commercial applications of aqueous developable ceramic compositions use acid-containing polymer binders and dilute aqueous base as a development solution. However, a totally aqueous development system can be formulated with the use of water-soluble polymer binders [22]. Ogawa proposes the use of nonionic water-soluble polymers, such as the cellulose ethers methyl cellulose, hydroxy methyl cellulose, hydroxy ethyl cellulose, and hydroxy propyl cellulose, as the polymeric binder. Molecular weights in the range of 30,000 to 1,(X)0,(X)0 are preferred in these compositions. When... 

Magnetic Resonance Imaging (MRI) becomes one of the useful microscopy and is used not only for the medical purposes but also for chemical applications. For polyurethane foams, the analysis of the distributions of many microstructural features, including strut length and window and cell shape distributions, were carried out. The diffusion behaviours of water in membrane is investigated by MRI in order to develop the polymer electrolyte fuel cells.The solvent diffusions and the swollen behaviors were investigated by MRI for hydroxy methyl cellulose,high amylose starch tablets, poly(ethylene methacrylate)/poly(2-hydroxyethyl methacrylate)-co-tetrahydro-... 

Product Agar Algin Carra-g eenan Furcel-1 aran Arabic Xan -tha n Traga- canth Hydroxy- propyl cellulose Locust bean Guar cmD Methyl cellulose Karaya... 

Hydroxy propyl cellulose, like methyl cellulose, is soluble in cold water but not in hot, precipitating above 38°C. It was introduced by Hercules in 1968 (Klucel) for such uses as adhesive thickeners, binders, cosmetics and as protective colloids for suspension polymerisation. The Dow company market the related hydroxypropylmethyl cellulose (Methocel) and also produce in small quantities a hydroxyethylmethyl cellulose. 

LMC is used in underwater concrete for both new construction and repair. The important requirements to obtain antiwashout capability, such as segregation resistance, flowability, self-leveling characteristics and lower bleeding are provided by the addition of viscosity-enhancing polymeric admixtures at polymer-cement ratios of 0.2-2.0%. These admixtures are water-soluble polymers, and classified under two groups, viz., cellulose types such as methyl cellulose and hydroxy ethyl cellulose and polyacrylamide types such as polyacrylamide and polyacrylamide-sodium acrylate [101]. 

Hydroxy propyl methyl cellulose (HPMC).35 HPMC is a partly O-methylated and 0-(2-hydroxypropylated) cellulose available in several grades that vary in viscosity and extent of substitution. It is used widely in pharmaceutical formulations, especially in oral products, as a tablet binder, in film coating, and as controlled release matrix. Soluble in cold water, it forms a viscous colloidal solution. For a 2% aqueous solution (20°C), viscosity can range from 2.4 to 120,000 mPa-s. High-viscosity grades can be used to retard the release of water-soluble drugs from a matrix. 

Jansen PJ, Kemp CA, Maple SR, Baertschi SW. Characterization of Impurities found by interaction of Duloxetine HC1 with enteric polymers hydroxy-propyl methyl cellulose acetate succinate and hydroxypropyl methylcellulose phthalaie. J Pharm Sci 1998 87(1) 81—85. 

This mechanism implies that a portion of the charred residue from the pyrolysis of cellulose could be derived from the secondary reactions involved in the decomposition of levoglucosan. In the production of levulinic acid, about 25 % of the initial D-glucose residues is converted into the humin that separates as an insoluble, charred residue. This humin could be formed from 5-(hydroxymethyl)-2-furaldehyde, which is readily polymerized and decomposed on heating under acid conditions. The kinetic investigations indicate that the humin could also be formed from the reaction of 5-(hydroxy-methyl)-2-furaldehyde with one of its precursors. ... 

Suspending agent systems such as a pseudoplastic (sodium carboxymethylcellulose) in combination with a clay (hydrated colloidal magnesium aluminum silicate) or blends and coprecipitates of sodium carboxymethylcellulose and microcrystalline cellulose exhibit some thixotropic flow characteristics. Other pseudoplastics such as hydroxyethylcellulose or hydroxy-propyl methyl cellulose may be required to overcome possible in compatibilities with sodium carboxymethylcellulose. 

Banker G, Peck G, Jan S, Pirakitikulr P. Evaluation of hydroxy-propyl cellulose and hydroxypropyl methyl cellulose as aqueous based film coatings. Drug Dev Ind Pharm 1981 7 693-716. 

Many ATPS systems contain a polymer which is sugar based and a second one which is of hydrocarbon ether type. Sugar-based polymers include dextran (Dx), hydroxy propyl dextran (HPDx), FicoU (Fi) (a polysaccharide), methyl cellulose (MC), or ethylhydroxyethyl cellulose (EHEC). Hydrocarbon ether-type polymers include poly (ethylene glycol) (PEG), poly (propylene glycol) (PPG), or the copolymer of PEG and PPG. De-rivatized polymers can also be useful, such as PEG-fatty acids or di-ethylaminoethyl-dextran (Dx-DEAE). 

Replaceable Gels (entangled polymer networks) linear polyacrylamide, methyl cellulose, hydroxypropylmethyl cellulose, hydroxy-ethylcellulose, polyethylene oxide, polyvinyl alcohol, agarose... 

Silica fume which is a by-product in the manufacture of ferrosilicon was used as a dispersant for carbon fibers in all the mixes. The chemical and physical properties of the silica fume is listed in Table 1. Polycarboxylie acid-type superplasticizer and hydroxy propyl methyl cellulose (HPMC, viscosity 3500-5600mPa s at 20°C as 2% aqueous solution) were employed as chemical admixtures. 

Drug formulations of dilitiazem hydrochloride also contain microcrystalline cellulose NF, sucrose stearate, eudragit, talc USP, magnesium stearate NF, hydroxy-propyl methyl cellulose USP, titanium dioxide USP, polysorbate NF, gelatin USP, etc. 

Collectors. Oleic acid, mixtures of oleic and linolic acid, sodium oleat, tall oil, saponified tall oil and mixtures of these substances, coriander oil, rape oil, mustard oil, pyridine base, water-soluble carbohydrates of the green oil type, also in saponated form, fatty acids and their salts, fish oil, hydroxy-ethylene-cellulose, carboxy-methyl-cellulose. 

The specific limits for the corresponding application can be found on the BfR website [115] MC = Methyl cellulose CMC = Carboxy methyl cellulose HEC = Hydroxy ethyl cellulose HEMC = Hydroxy ethyl methyl cellulose ... 

Materials. VEC was prepared by the catalyzed addition of CO2 to 3,4-epoxy-l-butene using conditions typical of that used industrially [77], then purified by vacuum distillation. Other raw materials were used as received without any additional purification. Mixed xylenes, vinyl acetate (VA), butyl acrylate (BA), butyl methacrylate (BMA), methyl methacrylate (MMA), styrene (St), and t-butyl hydroperoxide were obtained from Aldrich Chemical Company. Lupersol 575 (t-amyl peroxy (2-ethylhexanoate)) was supplied by Elf Atochem. Vazo 67 (2,2 -azobis(2-methylbutyronitrile)) was obtained from DuPont Chemical Company. Vinyl pivalate (NE05), vinyl 2-ethylhexanoate (V2EH), Tergitol NP-40 (non-ionic surfactant) and QP-300 (hydroxy ethyl cellulose) were obtained from Union Carbide Coq)oration. Aerosol OT-75 (surfactant) was obtained from Cytec. Sodium formaldehyde sulfoxylate was obtained from Henkel Corporation. Ethyl 3-ethoxy propionate (EEP), propylene glycol monomethyl ether (PM) and PM acetate (PM Ac) are Eastman Chemical Company products. 

However, one of the first matrices used for insolubilization of the aflBnant was cellulose that had been partially etherified with 3-hydroxy-phenoxy or 4-diazobenzyl groups (which react with diazotized protein or protein, respectively). Amino compounds may also be attached to the acid chlorides of carboxy polysaccharides.0-(3-Allyloxy-2-hydroxy-propyl)-cellulose and -Sephadex can be mercuriated and, in this form, used for isolation of thiolated antibodies and fractionation of mononucleotides according to their aflBnity for an organomercurial. Another mercurial, prepared by treatment of 0-(2-aminoethyl)Sephadex with IV-acetylhomocysteine thiolactone to give a thiol (49) which, on treatment with 2,5-bis[(acetoxymercuri) methyl]-1,4-dioxane, gives 50, can also be used in aflSnity chromatography of thiolated proteins. 

Gums, vegetable Hydrocarbon resins Hydroxy propyl cellulose Hydroxy propyl methyl cellulose Hydroxy propyl methyl cellulose acetate succinate (enteric)... 

Hydroxy propyl methyl cellulose phthalate (enteric)... 

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