Binder, tablet

EthylceUulose [9004-57-3], a cellulose either (qv), as prepared commercially, ie, of high DS, is thermoplastic and has alow density (1.14 g/cm ). It forms films of good thermostabiUty and excellent flexibiUty and toughness. EthylceUulose is used in lacquers, inks, and adhesives and is combined with waxes and resins in the preparation of hot-melt plastics. It is also used as a pharmaceutical tablet binder. 

Sodium carboxymethylcellulose is Hsted in the 1990 United States Pharmacopeia under the categories of pharmaceutic aid (suspending agent, tablet binder, viscosity-increasing agent), and cathartic tablets. 

The USP/NF provides a listing of excipients by categories in a table according to the function of the excipient in a dosage form, such as tablet binder, disintegrant, and such. An excellent reference for excipient information is the APA s Handbook of Pharmaceutical Excipients (1994). 

Staniforth JN, Chatrath M. Towards a new class of high functionality tablet binders. I Quasi-hornification of microcrystalline cellulose and loss of functionality. Pharm Res 1996 13 S208. 

Prosolv. Technical report tableting binder improves production. New York Penwest Pharmaceuticals, 2001. 

The ethyl ether of cellulose contains no less than 45% and not more them 50% ethoxy groups. It is available as a free-flowing stable white powder, insoluble in water, glycerol, and other hydrophilic solvents, but soluble in organic solvents such as ethanol, ethylacetate, and chloroform. This cellulose derivative is mainly used as a tablet binder. 

Bentonite Suspending agent Microcrystalline cellulose Tablet binder... 

Dibasic calcium phosphate Tablet binder Sodium hydroxide Alkaline agent... 

Hydroxy propyl methyl cellulose (HPMC).35 HPMC is a partly O-methylated and 0-(2-hydroxypropylated) cellulose available in several grades that vary in viscosity and extent of substitution. It is used widely in pharmaceutical formulations, especially in oral products, as a tablet binder, in film coating, and as controlled release matrix. Soluble in cold water, it forms a viscous colloidal solution. For a 2% aqueous solution (20°C), viscosity can range from 2.4 to 120,000 mPa-s. High-viscosity grades can be used to retard the release of water-soluble drugs from a matrix. 

Gum Arabic Pharmaceutical tablet binder Adhesive for miscellaneous paper 15... 

Tablet binder Substance used to cause adhesion of powder particles in tablet granulations Acacia, alginic acid, carboxymethylcellulose sodium compressible sugar, ethylcellulose gelatin, liquid glucose, metylcellulose povidone, pregelatinized starch...

Polymethacrylates —CO—O— Eilm former, tablet binder and diluent, sustained release polymer in right combinations... 

Galactomannans Made primarily of a linear mannose chain with galactose side groups Obtained from the powdered endosperm of certain seeds, guar gum Thickening agent and tablet binder... 

Stabilizing agent suspending agent sustained release adjuvant tablet binder tablet disintegrant viscosity-increasing agent. 

Carboxymethylcellulose sodium is widely used in oral and topical pharmaceutical formulations, primarily for its viscosity-increasing properties. Viscous aqueous solutions are used to suspend powders intended for either topical application or oral and parenteral administration. Carboxymethylcellulose sodium may also be used as a tablet binder and disin-tegrant, and to stabilize emulsions. ... 

Controlled-release vehicle stabilizing agent suspending agent tablet binder viscosity-increasing agent. 

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