Hydrogen peroxide vaporized

Other Sterilants. Sterilization methods, developed in response to the requirements of a low temperature, noncorrosive stedlant and rapid turnaround time required by most hospitals, include use of hydrogen peroxide vapor, hydrogen peroxide plasma, and peroxy acetic acid. Acceptance of these methods was not universal as of this writing (ca 1996). 

Colorimetric field tests for TATP and HMTD were described in Section 5 dealing with peroxide-based explosives. This group contains Keinan s PEX [85] (E. Keinan, Personal Communication, February 2006) and the kit developed by Schulte-Ladbeck et al., which involves also a preliminary stage to avoid falsepositive responses by non-explosive peroxides [86]. The color change of molybdenum hydrogen bronze suspension upon reaction with TATP was recommended also as a field test. Exposure of filter paper strips which were soaked in butanol suspension of the molybdenum compound to TATP or hydrogen peroxide vapors rapidly bleaches the blue color [87, 88]. 

Oberst FW, Comstock CC, Hackley EB Inhalation toxicity of ninety per cent hydrogen peroxide vapor—acute, subacute, and chronic exposures of laboratory animals. AMA Arch Ind Hyg Occup Med 10 319-327, 1954... 

Fig. 7. Absorption spectrum of hydrogen peroxide vapor. The absorption coefficient, a, is defined by the equation / = 70 exp (— atcd), where c is the concentration in molecules/cc. and d is the length of the light path in cm. Curve (a) and point O after Holt et al. (45,46). Curve (b) after Urey et al. (85). This figure based on refs. (46) and (85) with the permission of The Journal of Chemical Physics and the Journal of the American Chemical Society.

Edwards, L. M., Childers, R. W. Hydrogen peroxide vapor sterilization Applications in the production environment. In. M. J. Groves and R. Murty, eds. Aseptic Pharmaceutical Manufacturing II Applications for the 1990s. Buffalo Grove, IL Interpharm Press, pp. 415-466 (1995). 

Concentrated peroxide may decompose violently in contact with iron, copper, chromium, and most other metals or their salts, and dust (which frequently contains rust). Absolute cleanliness, suitable equipment (PVC, butyl, or Neoprene rubber), and personal protection are essential for safe handling. During concentration under vacuum of aqueous or of aqueous-alcoholic solutions of hydrogen peroxide, violent explosions occurred when the concentration was sufficiently high (probably above 90%). Detonation of hydrogen peroxide vapor has been studied experimentally.6... 

Nicovich, J.M., and P.H. Wine, Temperature-dependent absorption cross section of the hydrogen peroxide vapor, J Geophys Res 93, 2417, 1988. 

Jones, R., Drake, J., and Eagleson, D., Using Hydrogen Peroxide Vapor to Decontaminate Biological Safety Cabinets. Acumen, Baker Co, 1.1, Sanford, ME, 1993. 

Sterilized poly(ether imide)/PPE sulfone articles can be obtained in a hydrogen peroxide plasma or in hydrogen peroxide vapor [103]. Alternatively and previously, steam autoclaving was proposed [104]. 

Hydrogen peroxide vapor (HPV) is used for decontamination of BSCs. It is effective against a wide range of bacteria, viruses, and fungi. Equipment such as computers, complex instruments, and electronic parts are not adversely affected by HPV and there is no residue from its use. Generation of HPV requires special equipment and careful placement of units to ensure adequate decontamination. However, it is an environmentally friendly disinfectant since its products are oxygen and water. 

Verma AL, Soxena S, Sani GSS, Gaur V, Jaim VK (2011) Hydrogen peroxide vapor sensor using metal-phthalocyanine functionalized carbon nanotubes. Thin Solid Films 519 8144— 8148... 

Hazardous reactions. Hydrogen peroxide vapors can form sensitive contact explosives with hydrocarbons such as greases. Hazardous reactions ranging from ignition to explosion have been reported with alcohols, ketones, carboxylic acids (particularly acetic acid), amines and phosphorus. 

ENGINEERING CONTROLS Ventilation should be provided to minimize the release of hydrogen peroxide vapors and mists into the work environment. Spills should be minimized or confined immediately to prevent release into the work area. Remove contaminated clothing immediately and wash before reuse. 

Michael, J.V., D.A. Whytock, J.H. Lee, W.A. Payne, and L.J. Stief, L.J. (1977), Absolute rate constant for the reaction of atomic chlorine with hydrogen peroxide vapor over the temperature range 265 00 K, J. Chem. Phys., 67, 3533-3536. 

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