Human mammary epithelial cells

Waters KM, Shankaran H, Wiley HS, Resat H, Thrall BD. Integration of microarray and proteomics data for biological pathway analysis and network modeling of epidermal growth factor signaling in human mammary epithelial cells. Keystone Symposia, 2005. 

Rock, C.L., Kusluski, R.A., Galvez, M.M., Ethier, S.P. 1995. Carotenoids induce morphological changes in human mammary epithelial cell cultures. Nutr Cancer 23 319-333. 

Perou CM et al. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc Natl Acad Sci USA 1999 96 9212-9217. 

Z2. Zou, Z., Anisowicz, A., Hendrix, M., Thor, A., Neveu, M., Sheng, S., Rafidi, K., Seftor, E., and Sager, R., Maspin A serpin with tumor-suppressing activity in human mammary epithelial cells. Science 263, 526-529 (1994). 

Toouli, C. D., L. I. Huschtscha, A. A. Neumann, J. R. Noble, L. M. Colgin, B. Hukku, and R. R. Reddel. 2002. Comparison of human mammary epithelial cells immortalized by simian virus 40 T-Antigen or by the telomerase catalytic subunit. Oncogene 21(1) 128-39. 

Kim DH, Na HK, Oh TY, Kim WB, Surh YJ. (2004) Eupatilin, a pharmacologically active flavones derived from Artemisia plants, induces cell cycle arrest in ras-transformed human mammary epithelial cells. Biochem Pharmacol 68 1081-1087. 

Seewaldt VL, Mrozek K, Dietze EC, Parker M, Caldwell LE. Human papillomavirus type 16 E6 inactivation of p53 in normal human mammary epithelial cells promotes tamoxifen-mediated apoptosis. Cancer Res 2001 61 616-624. 

Warleta, F., Campos, M., Allouche, Y., Sanchez-Quesada, C., Ruiz-Mora, J., Beltran, G., and Gaforio, J. J. (2010). Squalene protects against oxidative DNA damage in mcflOa human mammary epithelial cells but not in mcf7 and mda-mb-231 human breast cancer cells. Food Chem. Toxicol. 48,1092-1100. 

Burchell, J., Durbin, H. and Taylor-Papadimitriou, J. 1983. Complexity of expression of antigenic determinants, recognized by monoclonal antibodies HMFG-1 and HM-FG-2, in normal and malignant human mammary epithelial cells. J. Immunol. 131, 508-513. 

Ceriani, R. L., Peterson, J. A., Lee, J. Y., Moncada, R. and Blank, E. W. 1983. Characterization of cell surface antigens of human mammary epithelial cells with monoclonal antibodies prepared against human milk fat globule. Somat. Cell Genet. 9, 415-427. Christie, W. W. and Wooding, F. B. P. 1975. The site of triglyceride biosynthesis in milk. Experientia 31, 1445-1447. 

Subbaramaiah K, Michaluart P, Chung WJ, Tanabe T, Telang N, Dannenberg AJ. 1999. Resveratrol inhibits cyclooxygenase-2 transcription in human mammary epithelial cells. Ann N Y Acad Sci 889 214-223. 

Chen ZH, Hurh YJ, Na HK, Kim JH, Chun YJ, Kim DH, Kang KS, Cho MH, Surh Y-J. 2004. Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells. Carcinogenesis 25 2005-2013. 

Dejmek, J., Safholm, A., Kamp Nielsen, C., Andersson, T. and Leandersson, K., 2006, Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase lalpha signaling in human mammary epithelial cells. Mol Cell Biol 26, 6024-36. 

Retinol, carotenoids, and tocopherol and risk of prostate cancer. J. Natl. Cancer Inst. 82,941-946. Ignatoski, K.M., Maehama, T., Markwart, S.M., Dixon, J.E., Livant, D.L., and Ethier, S.P. 2000. ERBB-2 overexpression confers PI 3 kinase-dependent invasion capacity on human mammary epithelial cells. Br. J. Cancer 82, 666-674. 

Alcorn J, Lu X, Moscow JA, et al. Transporter gene expression in lactating and nonlactating human mammary epithelial cells using real-time reverse transcription-polymerase chain reaction. J Pharmacol Exp Ther 2002 303 487-496. 

From other work, it appears possible that cell-specific effects could impact on the importance of certain transduction pathways that are associated with the ARE. Two independent studies that looked at the MAPK pathways involved in the regulation of human HO-1 induction in response to cadmium reported different findings. In MCF-7 human mammary epithelial cells, cadmium activated the ERK, JNK, and p38 MAPK pathways (90). These experiments employed pharmacological inhibitors and dominant-negative mutants to deduce that basal and... 

Leadon SA, Stampfer MR, Bartley J. 1988. Production of oxidative DNA damage during the metabolic activation of benzo(a)pyrene in human mammary epithelial cells correlates with cell killing. Proc Natl Acad Sci 85 4365-4368. 

Ghosh, A., Akech, J., Mukheijee, S., and Das, S.K. (2002). Differential expression of choUnephosphotrans-ferase in normal and cancerous human mammary epithelial cells. Biochem Biophys Res Common 297, 1043-8. 

E.O. Aboagye, Z.M. BhujwaUa, Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cells. Cancer Res. 59 (1999) 80. 

C. F., Zhu S. X., Lee J. C. F., Lashkari D., Shalon D., Brown P. O., and Botstein D. (1999) Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc Natl Acad Sci USA 96, 9212-7. 

Mammalian cells Human mammary epithelial cells DNA adducts No data + Leadon et al. 1995... 

Leadon SA, Sumerel J, Minton TA, et al. 1995. Coal tar residues produce both DNA adducts and oxidative DNA damage in human mammary epithelial cells. Carcinogenesis 16(12) 3021-3026. 

Lewis, A.)., Walle, U.K., King, R.S., Kadlubar, F.F., Falany, C.N., and Walle, T. (1998) Bioadivation of the cooked food mutagen N-hydroxy-2-amino-l-methyl-6-phenylimidazo[4,5-i>] pyridine by estrogen sulfotransferase in cultured human mammary epithelial cells. Carcinogenesis, 19, 2049-2053. 

Chen, Z.H., Na, H.K., Hurh, Y.J., and Surh, Y.J. (2005) 4-Hydroxyestradiol induces oxidative stress and apoptosis in human mammary epithelial cells ... 

The role of BGRP in drug accumulation into milk can be illustrated by examining the M/S of BGRP substrates in knockout mice (Table 7.5). Members of the OATP and MRP families also have been detected in human mammary epithelial cells. P-GP is not highly expressed in mammary epithelial cells and lactation appears to down regulate its mRNA levels (Alcorn et al., 2002). 

B.S. Hendriks, G. Orr, A. Wells, H.S. Wiley, D.A. Lauffenburger, Parsing ERK activation reveals quantitatively equivalent contributions from epidermal growth factor receptor and HER2 in human mammary epithelial cells,/. Biol. Chem. 2005, 280, 6157-6169. 

Martin, P., Brignon, G., Furet, J.P. and Leroux, C. (1996) The gene encoding a,i-casein is expressed in human mammary epithelial cells during lactation. Lait, 76, 523-35. 

---