Histoplasmosis diagnosis

Suggested Alternatives for Differential Diagnosis Abdominal aneurysm, aortic dissection, pleural effusion, subarachnoid hemorrhage, superior vena cava syndrome, hantavirus pulmonary syndrome, mediastinitis, fulminate mediastinal tumors pneumonia, gastroenteritis, meningitis, ecthyma, rat bite fever, spider bite, leprosy, plague, tularemia, coccidioidomycosis, diphtheria, glanders, histoplasmosis, psittacosis, typhoid fever, and rickettsial pox. 

Suggested Alternatives for Differential Diagnosis Influenza, infectious mononucleosis, hepatitis, leptospirosis, infective endocarditis, malaria, tuberculosis, typhoid fever, cryptococcosis, histoplasmosis, ankylosing spondylitis and undifferentiated spondyloarthropathy, collagen vascular disease, chronic fatigue syndrome, malignancy, and osteomyelitis. 

Suggested Alternatives for Differential Diagnosis Bartonellosis, brucellosis, other causes of encephalitis, coxsackieviruses, cryptococcosis, cysticercosis, cytomegalovirus, histoplasmosis, legionellosis, leptospirosis, listeria, lyme disease, malaria, rabies, tuberculosis, mumps, stroke, metabolic encephalopathy, Reye syndrome, Bartonella infection, Naegleria infection, Ebstein-Barr virus, prion disease, toxic ingestions, and AIDS. 

In most patients, serologic evidence remains the primary method in the diagnosis of histoplasmosis. Results obtained from complement fixation, immunodiffusion, and latex antigen agglutination antibody tests are used... 

In the AIDS patient with progressive disseminated histoplasmosis, the diagnosis is best established by bone marrow biopsy and culture, which yield positive cultures in 90% of patients. 

Diagnosis of CMV retinitis The diagnosis should be made by indirect ophthalmoscopy. Other conditions in the differential diagnosis of CMV retinitis include candidiasis, toxoplasmosis, histoplasmosis, retinal scars, and cotton wool spots, any of which may produce a retinal appearance similar to CMV. The... 

Serology The detection of specific antibodies does not play any role in the diagnosis of superficial or cutaneous mycoses, but has its place in systemic candidiasis, aspergillosis and especially cryptococcosis, histoplasmosis and coccidioidomycosis. 

Posterior uveitis is rarely a stand-alone diagnosis. Rather, this term is typically used to describe the manifestations of numerous inflammatory conditions involving the choroid and/or retina. The more common etiologies of posterior uveitis include toxoplasmosis, sarcoidosis, syphilis, histoplasmosis, and retinal white-dot syndromes. These conditions may affect a wide range of individuals with regard to age, gender, race, and national origin. 

A so-called porcelain liver should be clarified by differential diagnosis. (188) This condition is characterized by focal calcareous deposits in the liver capsule, which can be detected by X-ray examination as well as by sonography and CT. It may be caused by phleboliths, pseudolipoma, histoplasmosis, calcified larvae, small capsule haematomas, small abscesses, etc. 

Subacute and chronic HP may mimic virtually any ILD. Differential diagnosis of the subacute form of the disease includes some granulomatous lung infections such as tuberculosis or histoplasmosis, noninfectious granulomatous lung disorders, i.e., sarcoidosis, and some other ILD like lymphoid interstitial... 

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