Hantavirus pulmonary syndrome

Pulmonary vascular endothelial damage with fluid extravasation and necrosis of surrounding tissue 

Arterial pressure - decreased (hypotension) [7] Breathing - difficult, rest (rest dyspnea) Breathing - rapid (tachypnea) 

Blood ELISA antibodies - positive Blood Hgb, Hct - increased [5] 

parenchyma general - infiltrates Lungs, pleura - fluid (pleural effusion) 

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Suggested Alternatives for Differential Diagnosis Abdominal aneurysm, aortic dissection, pleural effusion, subarachnoid hemorrhage, superior vena cava syndrome, hantavirus pulmonary syndrome, mediastinitis, fulminate mediastinal tumors pneumonia, gastroenteritis, meningitis, ecthyma, rat bite fever, spider bite, leprosy, plague, tularemia, coccidioidomycosis, diphtheria, glanders, histoplasmosis, psittacosis, typhoid fever, and rickettsial pox. 

Patients should receive treatment for secondary infections. Unless clearly indicated, clinicians should avoid using intravenous lines, catheters and other invasive techniques that increase the risk of hemorrhage. VHP patients require attention to pulmonary toilet, specifically the usual measures necessary to avoid superinfection, and the provision of supplementary oxygen. Clinicians should avoid using steroids and other immunosuppressive agents, which have no empiric benefit, except for treatment of Hantavirus Pulmonary Syndrome (HPS) (48). 

Centers for Disease Control and Prevention. Hantavirus Pulmonary Syndrome - United States Updated Recommendations for Risk Reduction Morbidity and Mortality Weekly Report, 51(RR-9), My 26, 2002... 

Custer, DM, Thompson, E, Schmaljohn, CS, Ksiazek, TG, Hooper, JW. Active and Passive Vaccination against Hantavirus Pulmonary Syndrome with Andes Virus M Genome Segment-Based DNA Vaccine. Journal of Virology, 77(18) 9894-9905, 2003... 

Cyanide poisoning Ethylene glycol poisoning Hantavirus pulmonary syndrome Hemorrhagic fever with renal syndrome Lewisite poisoning Malaria... 

Hantavirus pulmonary syndrome A (virus) Zoonosis—may be vector-borne... 

Moolenaar RL, Dalton C, Lipman HB, et al. Clinical features that differentiate hantavirus pulmonary syndrome from three other acute respiratory illnesses. Clin Infect Dis. 1995 21 643-649. 

Nolte KB, Feddersen RM, Foucar K, et al. Hantavirus pulmonary syndrome in the United States A pathological description of a disease caused by a new agent. Hum Pathol. 1995 26 110-120. 

Zaki SR, Greer PW, Coffield EM, et al. Hantavirus pulmonary syndrome. Pathogenesis of an emerging infectious disease. Am J Pathol. 1995 146 552-579. 

Zaki SR, Khan AS, Goodman RA, et al. Retrospective diagnosis of hantavirus pulmonary syndrome, 1978-1993. Implications for emerging infectious diseases. Arch Pathol Lab Med. 1996 120 134-139. 

Hantaan virus is still active in Korea, Japan, and China. Seoul virus causes a milder form of HFRS, and may be distributed worldwide. There are a number of other hantaviruses that are associated with HFRS, including Puumala virus, which is associated with chronically infected bank voles (Clethrionomys glareolus). Recently in the United States, a new hantavirus (Sin nombre virus) has been associated with the hantavirus pulmonary syndrome (HPS).9... 

Butler JC, Peters CJ. Hantaviruses and Hantavirus Pulmonary Syndrome. Clin Infect Dis. 1994 19 387-395. 

Early on, it was aLso established that person-to-person. spread was unlikely. It was also determined that this "new " hantavirus had actually been present, but unrecognized, at least as early as 1959. Since the 1993 outbreak, hantavirus pulmonary syndrome (HPS) has been identified in over half of the states of the U.S. 

So just how do people get hantavirus pulmonary syndrome (HPS) It all starts with rodents, like tile deer mouse and cotton rat, which carry hantaviruses. 

CDC. 1994b. Hantavirus Pulmonary Syndrome, United States, 99 i. Morbidity and Mortality Weekly Report 43 45-48. 

Venezuelan equine encephalitis virus Viruses causing hantavirus pulmonary syndrome Yellow fever virus... 

Hantavirus pulmonary syndrome (HPS) The Sin Nombre hantavirus responsible for severe respiratory illness. 

Hansen s Disease The preferred name for leprosy, caused by Mycobacterium leprae, it exhibits various clinical forms ranging from tuberculoid to lepromatous. Hantavirus Pulmonary Syndrome (HPS) The Sin... 

Hantavirus Pulmonary Syndrome (HPS)—HPS is a fairly uncommon, newly recognized, and potentially deadly disease found in North America. Once its nonspecific flu-like symptoms appear, immediate intensive care is essential. Hantaviruses are carried by rodents, especially the deer mouse, and can infect humans who are exposed to mouse droppings. 

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