High-energy collision induced

Nizigiyimana, L. Rajan, P.K. Haemers, A. Claeys, M. Derrick, P.J. Mechanistic Aspects of High-Energy Collision-Induced Dissociation Proximate to the Charge in Saturated Fatty Acid n-Butyl Esters Ca-tionized With Lithium. Evidence for Hydrogen Radical Removal. Rapid Commun. Mass Spectrom. 1997, 11, 1808-1812. 

Griffiths WJ, Alvelius G, Liu S, Sjovall J (2004) High-energy collision-induced dissociation of oxosteroids derivatised to Girard hydrazones. Eur J Mass Spectrom (Chichester, Eng) 10 63-88... 

Yates, J.R., Eng, J.K., Clauser, K.R. and Burlingame, A.L. (1996) Search of sequence databases with uninterpreted high-energy collision-induced dissociation spectra of peptides. J. Am. Soc. Mass Spectrom., 7 (11) 1089-98. 

Nizigiyimana, L., Van Den Heuvel, H. and Claeys, M. (1997) Comparison of low- and high-energy collision-induced dissociation tandem mass spectrometry in the analysis of ricinoleic and ricinelaidic acid. J. Mass Spectrom., 32 (3), 277-86. 

Retention of the terminal amine also allows the potential for further modification of the peptide with sensitivity-enhancing molecules such as the C-5 alkyl quaternary ammonium activated ester developed in this laboratory (Figure 5). N-terminal derivatisation of peptides with fixed-charge compounds including quaternary amines, phosphonium and pyridinium ions have already been shown to simplify the daughter-ion spectra of peptides produced by high-energy collision-induced... 

Once the exact mass is determined for the precursor ion, the instrument is switched to tandem MS mode (TOF/TOF mode) and fragment ions are generated using laser-induced dissociation (LID) and/or high energy collision-induced dissociation (CID) (13) (see Note 12). 

Macht, M., Asperger, A., and Deininger, S. O. (2004) Comparison of laser-induced dissociation and high-energy collision-induced dissociation using matrix-assisted laser desorption/ionization tandem time-of-flight (MALDI-TOE/TOF) for peptide and protein identification. Rapid Commun. Mass Spectrom. 18, 2093-2105. 

The main advantage of the FAB technique compared to ESI and MALDI is, in fact, not the ionization method itself but the type of mass analyzer it works with. FAB ion sources are usually attached to magnetic sector, double-focusing mass spectrometers, enabling accurate mass measurements and, which is even more important, allowing the study of high-energy collision-induced dissociation (CID) reactions which provide information about the structure of the studied ion (see next section). 

Bottrill, A. R., Giannakopulos, A. E., Waterson, C., Haddleton, D. M., Lee, K. S., and Derrick, P. J., Determination of End-Groups of Synthetic Polymers by Matrix-Assisted Laser Desorption/Ionization High-Energy Collision-Induced Dissociation, Anal. Chem., 71, 3637,1999. 

D. J. Harvey, R. H. Bateman, and B. N. Green, High-energy collision-induced fragmentation of complex oligosaccharides ionized by matrix-assisted laser desorption/ ionization mass spectrometry, 7. Mass Spectrom. 32, 168-187 (1997). 

B. Kilster, T. J. P. Naven, and D. J. Harvey, Effect of the reducing-terminal substituents on the high energy collision-induced dissociation matrix-assisted laser desorption/ionization mass spectra of oligosaccharides. Rapid Commun. Mass Spectrom. 10, 1645-1651 (1996). 

Biemann, K. (1990) Sequencing of peptides by tandem mass spectrometry and high-energy collision-induced dissociation. Methods Enzymol., 193, 455-479. 

Wang, Y, Hornshaw, M., Alvelius, G., Bodin, K., Liu, S., Sjovall, I, Griffiths, W.J. (2006) Matrix-assisted laser desorption/ionization high-energy collision-induced dissociation of steroids analysis of oxysterols in rat brain. Anal. Chem., 78(1), 164-173. 

Fagerquist, C.K., WiUiams, K.E., Bates, A.H. (2007) Identification of foodborne bacteria by high energy collision-induced dissociation of their protein biomarkers by MALDI tandem-time-of-flight mass spectrometry. In Proceedings of the 55th American Society of Mass Spectrometry Conference, June 3-7, Indianapolis, IN [DVD MPT-327 from ASMS]. 

Yalcin, T., Gabryelski, W, Li, L. (2000) Structural analysis of polymer end groups by electrospray ionization high-energy collision-induced dissociation tandem mass spectrometry. Anal. Chem., 72(16), 3847-3852. 

Pittenauer E, Allmaier G. High-energy collision induced dissociation of biomolecules MAL-DI-TOF/RTOF mass spectrometry in comparison to tandem sector mass spectrometry. Comb Chem High Throughput Screen. 2009 12 137-55. 

ParkT, Park YS, Rho JR, Kim YH. Structural determination of cerebrosides isolated fi om Asterias amuremis starfish eggs using high-energy collision-induced dissociation of sodium-adducted molecules. Rapid Commun Mass Spectrom. 2011 25 572-8. 

Falick, A. M., Hines, W. M., Medzihradsky, K. F., Baldwin, M. A., and Gibson, B. W. (1993) Low-mass ions produced from peptides by high energy collision-induced dissociation in tandem mass spectrometry. J. Am. Soc. Mass Spectrom. 4,882-893. 

Lewandrowski, U. Resemann, A. Sickmann, A. Laser-induced dissociation/high-energy collision-induced dissociation fragmentation using MALDI-TOF/TOF-MS instrumentation for the analysis of neutral and acidic oligosaccharides. Anal. Chem. 2005, 77, 3274-3283. 

Clayton, E. Bateman, R. H. Time-of-flight mass analysis of high-energy collision-induced dissociation fragment ions. Rapid Common. Mass Spectrom. 1992, 6, 719-720. 

Fabris, D., Kelly, M., Murphy, C., Wu, Z., and Fenselau, C., 1993, High-Energy Collision-Induced Dissociation of Multiply Charged Polypeptides Produced by electrospray. In J.Amer.Soc.Mass Spectrom., 4, 652-661... 

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