Hexanoate salt

Diazabicydoudecene and its ethyl hexanoic salt Epoxy/novolac, epoxy/anhydrides... 

However the acid is prepared, the sodium salt may be prepared as described in U.S. Patent 3,503,967 Five liters of methylene chloride were added to a clean dry vessel equipped with stirrer. 7-[a(4-pyridylthio)acetamido] cephalosporanic acid (1,000 g) was added to the vessel, followed by 350 ml of triethylamine. The resultant solution was treated with decolorizing charcoal for 15 minutes and filtered. A solution of sodium-3-ethyl-hexanoate (27.3%) in butanol-methylene chloride was added to the filtrate with stirring. Seven thousand five hundred milliliters of acetone was added. Crystallization occurred while stirring was continued several hours under dry conditions. The crystals were collected by filtration, washed with large volumes of acetone, and then dried in vacuo at 50°C to yield about 950 g of the title compound. 

To this acid was then added 1 g of 4-ethyl-2,3-dioxo-1-piperazinocarbonyl chloride (from the reaction of N-ethylethylenediamine and diethyl oxalate to give 2,3-dioxo-4-ethyl-piperazine which Is then reacted with phosgene) and the resulting mixture was reacted at 15°C to 20°C for 2 hours. After the reaction, a deposited triethylamine hydrochloride was separated by filtration, and the filtrate was incorporated with 0.4 g of n-butanol to deposit crystals. The deposited crystals were collected by filtration to obtain 1.25 g of white crystals of 6-[ D(—l-Ct-(4-ethyl-2,3-dioxo-1 -piperazinocarbonylaminolphenylacetamido] penicillanic acid. Into a solution of these crystals in 30 ml of tetrahydrofuran was dropped a solution of 0.38 g of a sodium salt of 2-ethyl-hexanoic acid in 10 ml of tetrahydrofuran, upon which white crystals were deposited. The deposited crystals were collected by filtration, sufficiently washed with tetrahydrofuran and then dried to obtain 1.25 g of sodium salt of 6-[D(—)-a-(4-ethyl-2,3-di-0X0-1-piperazinocarbonylaminolphenylacetamido] penicillanic acid, melting point 183°C to 185°C (decomposition), yield 90%. 

Are used to accelerate autoxidation and hardening of oxidisable coatings. Metal soaps, used as paint driers, can be made from a variety of carboxylic acids, including the commercially important naphthenic and 2-ethyl hexanoic acids, tall oil, fatty acids, neodecanoic and isononanoic acid. Cobalt is unquestionably the most active drier metal available. Metallic driers such as cobalt naphthenate or octoate and zinc salts can interact with UVAs, HALS, or AOs. 

The filtrate was brought to pH = 1.8 with 10% hydrochloric acid. The ether layer was separated and the aqueous layer washed with ethyl acetate (3x2 L). The combined organic layers were washed with 5% KHS04 (3x1 L), water (3 x 1 L) and brine (1 L), dried over magnesium sulfate and concentrated in vacuo to yield 398.9 g of crude [R,lS,4S]-4-Cyclohexyl-l-[[[2-methyl-l-(l-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline, monosodium salt (isomer B). The crude product was dissolved in acetone (4393 ml), treated with a solution of 2-ethyl hexanoic acid, sodium salt (117.3 g) in acetone (1468 ml), then stirred at room temperature overnight. The resultant precipitate was collected by filtration, washed with acetone (3 x 400 ml) and hexane (1 L) then dried in vacuo. Yield 277 g, m.p. 195-196°C, [a]D= -5.1° (MeOH, c = 2), HI = 99.8%. Isomer "A" was not detectable. 

The reaction was of general applicability not only internal but also terminal alkynes reacted in the same way, e.g. 1-hexyne was converted into hexanoic acid (58%) and 2-ethynylthiophene to 2-thienylacetic acid (54%). By contrast, heating terminal alkynes in chloroform with HTI afforded alkynyl or alkenyl phenyliodonium salts the former in refluxing methanol rearranged to methyl carboxylates [11],... 

The oxidation of cyclohexane is accompanied by the oxidative degradation of the products. In other words, the products themselves undergo metal-initiated radical chain oxidation. For this reason oxidation is normally carried out at low conversions when the selectivity to the desired products is high. The catalysts used are a mixture of hydrocarbon soluble carboxylate salts of Co2+ and Mn2+ or Cr3+. Due to the better solubility properties, salts of long-chain carboxylic acids such as 2-ethyl hexanoic or naphthenic acids are favored. As already mentioned, the primary role of the metal ions is to act as catalysts for the initiation steps. In other words, the metal ions undergo redox reactions with 8.9 to give 8.10 and 8.11. 

The full impact of Pd-catalysed deprotection of ally esters was first appreciated by Jeffrey and McCombie149 who showed that an allyl ester could be deprotected to the potassium salt of the corresponding carboxylic acid under Pd catalysis — a transformation that is particularly valuable for acid-sensitive substrates.130 In the example shown in [Scheme 6.57], the displacement of the exchange equilibrium over to the desired product was assured by employing the sodium salt of 2-ethyI-hexanoate. which is soluble in most common solvents except hydrocarbons.151... 

Sodium-2-ethyl hexanoate will precipitate the sodium salt of N-derivatized cephalosporin C from solvents (29,30). 

In addition to tin compounds such as dibutyltin dilaurate and dibutyltin diacetate, various other metal compounds have been claimed to be effective deblocking catalysts such as zinc naphthenate (70), lead naphthenate, bismuth salts, and titanates (71), and Ca, Mg, Sr, or Ba salts of hexanoic, octanoic, naphthenic, or linolenic acid (72) and metal acetyl acetonates (73). Also combinations of organotin compounds and quaternary ammonium salts have been claimed to have a synergistic effect in lowering the deblocking temperature (74). 

Cadmium 2-ethylhexanoate Cadmium 2-ethylhexoate Cadmium bis(2-ethylhexanoate) Cadmium di-2-ethylhexylate Cadmium ethylhexanoate EINECS 219-346-0 Hexanoic acid. 2-ethyl-, cadmium salt HSDB 6140. 

Calcium 2-ethylhexanoate Calcium bis 2-ethyl-hexanoate) EINECS 205-249-0 Hexanoic acid, 2-ethyi-, calcium salt. 

SEH-C0 C 101 C 101 (catalyst) CO 12 Cobalt 2-ethylhexoate Cobalt bis(2-ethylhexanoate) Cobalt octoate Cobalt(ll) 2-ethylhexanoate Cobaltous 2-ethylhexanoate Coballous octoate EINECS 205-250-6 Hexanoic acid, 2-ethyl-, cobalt(2- -) salt HSDB 5621 NL 49P NL 51P NL 51S Versneller NL 49. 

EINECS 221-625-7 2-Ethylhexanoic acid, potassium salt Hexanoic acid, 2-ethyl-, potassium salt Potassium 2-ethylhexanoate. 

EINECS 205-251-1 Hexanoic acid, 2-ethyl-, zinc salt Octoate Z Zinc 2-ethylhexoate Zinc bis(2-ethyl-hexanoate). Rubber activator used in soluble cure systems in place of stearic acid and partial replacement of zinc oxide for natural and synthetic rubbers. Vanderbilt R.T. Co. Inc. 

Hydroxyimino)hexanoic acid 262 85 % Sulfuric acid (30 g), in 400-ml beaker, is cooled in ice-salt and to it is added slowly, with stirring, ethyl 2-butylacetoacetate (18.6 g, 0.1 mole), the temperature being kept below —5°. The butyl nitrite (0.1 mole + 5% excess 11 g) is dropped in at about 0° at such a rate that there is gentle effervescence but no noticeable evolution of nitrogen oxides. The acid is then diluted by addition of small pieces of ice, whereupon the hydroxyimino ester separates as a white cheesy precipitate. Cold water is added and the mixture is extracted with ether. The ethereal solution is shaken with cold 10% sodium hydroxide solution, in which the hydroxyimino compound dissolves with a red color. The alkaline solution is heated for 15 min on a water-bath, then cooled and acidified. The 2-(hydroxyimino)hexanoic acid that separates is filtered off and the filtrate is extracted with ether. Recrystallization from light petroleum gives a product of m.p. 136° (dec.) in 86% yield. 

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