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Hepatoprotection effect

Flavonoids Apocynum venetum Silanizsilica MeOH + HP UV Hepatoprotective effect 87... [Pg.266]

Trabectedin is licensed for the treatment of advanced soft-tissue sarcoma when treatment with anthracyclines and ifosfamide has failed or is contraindicated. It is administered by intravenous infusion. Trabectedin may cause hepatobiliary disorders and for this reason hepatic function should be evaluated before starting treatment and during treatment. Dexamethasone is administered intravenously with trabectedin for its anti-emetic and hepatoprotective effects. As with other antineoplastic drugs, trabectedin causes nausea and vomiting and bone-marrow suppression as side-effects. [Pg.156]

Tridevi NP, Rawal UM, Patel BP. (2007) Hepatoprotective effect of andrographolide against hexachlorocyclohexane-induced oxidative injury. Integr... [Pg.363]

Fouad, A. A., El-Rehany, M. A., and Maghraby, H. K. (2007). The hepatoprotective effect of carnosine against ischemia/reperfusion liver injury in rats. Eur. J. Pharmacol. 572, 61-68. [Pg.138]

Tayal, V. et al. (2007) Hepatoprotective effect of tocopherol against isoniazid and rifampicin induced hepatotoxicity in albino rabbits. Indian Journal of Experimental Biology, 45 (12), 1031-1036. [Pg.381]

Nunez-Alarcon, J. and Quinones, M., Epicuticular flavonoids from Haplopappus baylahuen and the hepatoprotective effect of the isolated 7-methylaromadendrin, Biochem. Syst. Ecol, 23, 453, 1993. [Pg.724]

Extracts of leaves of Combretum quadrangulare showed promising hepatoprotective effect on D-GalN or tumor necrosis factor-a (TNF-a)-induced cell death in primary cultured mouse hepatocytes. The hepatoprotective effect of C-glycosylflavones from C. quadrangulare was determined by evaluation of the serum enzyme level in comparison with the o-GalN or TNF-a treated control. At the concentration of 200 pg/ml, orientin and isoscoparin possessed an inhibitory effect on TNF-a-induced cell death of about 20%, while vitexin at 100 pg/ml produces a 95%i inhibitory effect. [Pg.901]

Banskota, A.H. et al., Hepatoprotective effect of Combretum quadrangulare and its constituents, Biol. Pharm. Bull, 23, 456, 2000. [Pg.904]

Polyphenols are also endowed to have hepatoprotective effects. For example, quercetin reduces liver oxidative damage, ductural proliferation and fibrosis in biliary-ostructed rats, suggesting that it may... [Pg.298]

Higuchi et d. reported an assay method using in vitro immunological liver injury and confirmed the hepatoprotective effects of total OG from soybeans [32]. They used an antiserum against rat plasma membranes as a lesion model of liver cells. In a series of studies on hepatoprotective drugs,... [Pg.100]

HEPATOPROTECTIVE EFFECT OF PLANT COMPONENTS INHIBITION OF TUMOR NECROSIS FACTOR-a-DEPENDENT INFLAMMATORY LIVER... [Pg.459]

Curcumin (9) is an arylheptanoid isolated from turmeric, the rhizome of Curcuma longa L. Turmeric has been used as a remedy for inflammatory in Asia for centuries. There are a number of reports supporting an anti-inflammatory effect of curcumin. Its hepatoprotective activity against inflammatory liver injury was also demonstrated in a recent study [105], where pretreatment with curcumin (50 mg/kg, p.o.) significantly inhibited the elevation of serum transaminase activities after intoxication with D-GalN and LPS in mice. The hepatoprotective effect is presumably... [Pg.469]

There is much interest in the pharmacological role of dietary nutrients in human health. Some nutrients have been recognized to have a hepatoprotective effect through interaction with TNF-a. For instance, dietary supplementation (5%, at the exp ense of casein) with glycine (30), a non-essential amino acid, attenuated LPS-induced liver injury and... [Pg.474]

Extract from artichoke, Cynara scolymus L., has been used in folk medicine against liver complaints and such extracts or several constituents thereof have been claimed to exert a hepatoprotective effect... [Pg.943]

Morita, T., Jinno, K., Kawagishi, H., Arimoto, Y., Suganuma, H., Inakuma, T. and Sugiyama, K. (2003) Hepatoprotective effect of myristicin from nutmeg (Myristica fragrans) on lipopolysaccharide/ D-galactosamine-induced liver injury, journal of Agriculture and Food Chemistry 51 (6), 1 560-1 565. [Pg.187]

Ueno Y, et al. Orally-administered caspase inhibitor PE-03491390 is retained in the liver for prolonged periods with low systemic exposure, exerting a hepatoprotective effect against alpha-Fas-... [Pg.180]

Russian investigators have reported a hepatoprotective effect of a plant product Galstena in a rat model and have extended their observations to a clinical trial, with favorable results however, few data were given in this report (30). [Pg.325]

See other pages where Hepatoprotection effect is mentioned: [Pg.338]    [Pg.792]    [Pg.945]    [Pg.96]    [Pg.99]    [Pg.100]    [Pg.106]    [Pg.111]    [Pg.459]    [Pg.465]    [Pg.466]    [Pg.467]    [Pg.468]    [Pg.471]    [Pg.472]    [Pg.473]    [Pg.474]    [Pg.223]    [Pg.192]    [Pg.137]    [Pg.114]    [Pg.234]    [Pg.240]    [Pg.391]    [Pg.30]    [Pg.383]    [Pg.869]    [Pg.325]   
See also in sourсe #XX -- [ Pg.356 ]



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