Groups Hawaii

History. Methods for the fractionation of plasma were developed as a contribution to the U.S. war effort in the 1940s (2). Following pubHcation of a seminal treatise on the physical chemistry of proteins (3), a research group was estabUshed which was subsequendy commissioned to develop a blood volume expander for the treatment of military casualties. Process methods were developed for the preparation of a stable, physiologically acceptable solution of alburnin [103218-45-7] the principal osmotic protein in blood. Eady preparations, derived from equine and bovine plasma, caused allergic reactions when tested in humans and were replaced by products obtained from human plasma (4). Process studies were stiU being carried out in the pilot-plant laboratory at Harvard in December 1941 when the small supply of experimental product was mshed to Hawaii to treat casualties at the U.S. naval base at Pead Harbor. On January 5, 1942 the decision was made to embark on large-scale manufacture at a number of U.S. pharmaceutical plants (4,5). 

Perhaps the most useful contribution made by flavonoids in this group of plants, however, was the assistance they provided in studies of natural hybridization between Dubautia scabra and D. ciliolata (Crins et al., 1988a). Dubautia scabra is a pioneer plant that colonizes new lava moderately D. ciliolata occurs on somewhat older lava. Where newer flows overlap older ones, one can often find plants with features intermediate between the two species. This phenomenon is readily observed in the vicinity of Kilauea Volcano on the island of Hawaii, where one finds D. scabra subsp. scabra on newer substrate and D. ciliolata subsp. glutinosa on the older substrate. Since the two taxa exhibit different flavonoid profiles, and we know that flavonoid profiles are inherited in an additive fashion, hybrids would be expected to exhibit flavonoid markers inherited from each parent. A major advantage in this study was the availability of known Fj hybrids that had been produced from controlled crosses at the University of Hawaii (by G. D. Carr). Analysis of the... 

The Hawaii-Los Angeles Multiethnic Cohort study, a prospective study of 212,000 men and women from four racial-ethnic groups in Hawaii and Los Angeles. 

From another shallow-water variety of L majuscula found in Hawaii, a new crystalline metabolite pukeleimide C (102) was isolated. The structure was secured by X-ray studies [163]. Chiroptical studies showed the compound to be racemic and, probably, an artefact. A separate collection of the cyanophyte did not contain pukeleimide C but, instead, yielded a group of related metabolites, e.g. 103, whose structures were assigned from spectral data [164], Unfortunately, no information is available on the bioactivity of these metabolites. 

Uoamines A (172) and B (173) are piperidine alkaloids, isolated from Aplidium uouo from Maui, Hawaii. They differ only in the geometry of the 3-thiomethylacrylate ester group [168]. 

Trimedlure may exist in eight different isomeric forms, depending on which of the four dotted lines of Figure 3 the chlorine atom resides upon, and whether the methyl and ester groups are cis or trans. Our preparations of trimedlure are not pure compounds but mixtures of isomers. Trimedlure has been separated into two solid isomers and a liquid fraction. Tests at our Hawaii laboratory indicated that one of the solids and the liquid portion of trimedlure are attractive, but the other solid is not attractive 91). Apparently, stereoisomerism can play an important role in insect attraction. 

This general aromatic anneiation Finally, the pyridine synthesis is simply a double enamine/imine formation between ammon . sequence came from Hawaii and the two carbonyl groups. Probably the aldehyde reacts first. 

Mero, J.L., 1965. The Mineral Resources of the Sea. Elsevier, Amsterdam, 312 pp. Morgenstein, M., 1973. The origin and distribution of manganese nodules in the Pacific and prospects for exploration. Symposium, Honolulu Hawaii, 23—25 July, 1973, Valdevia Manganese Exploration Group, Univ. Hawaii, and IDOE-NSF. 175 pp. 

National Arsenic Occurrence Survey (NAOS) sampled raw water from approximately 270 public supply wells in all 50 states, and predicted arsenic concentrations in finished water based on known treatments implemented by the systems (Frey and Edwards, 1997). Frey and Edwards (1997) also provided national estimates based on reexamining the NIRS data and a dataset of finished water from 60 large systems (serving >10,000 people) sampled by the Metropolitan Water District of Southern California (Davis et al, 1994). In 1973 to 1997, the USGS analyzed for arsenic in 18,850 raw-water samples from wells in 49 states (all but Hawaii) and Puerto Rico this dataset included 2,262 samples from public supply wells (Focazio et al., 2000). Several older national surveys of arsenic have been described in documents prepared for the USEPA (ISSI Consulting Group et al., 2000). 

Millions of pounds of chemical warfare agents are stored throughout the world. Their destruction by incineration at high temperatures, up to 2500°F (1480°C) is planned or under way in several countries. These include eight sites in the United States, such as the Tooele Army Depot in Utah and Johnston Atoll in the Pacific, which is 750 miles from Hawaii. Some of the ordinance has been stored since World Wars I and II. Complaints have been lodged by citizens groups concerned about possible risks to residents during the destruction of the chemicals. 

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