Gluteus

GOLD COMPOUNDS. Aurothioglucose and gold sodium thiomalate are given intramuscularly, preferably in the upper outer quadrant of the gluteus muscle. The nurse gives auranofin orally. 

Haloperidol and fluphenazine decanoate should be administered by a deep, Z-track IM method. Long-acting risperidone is injected by deep IM injection in the gluteus maximus, but Z-tracking is not necessary. 

Fig. 5. Standard fast spin-echo imaging of the pelvis and the lower leg. Typical contrasts between musculature and other tissues are demonstrated. Bl = bladder, Fe = femur. Gluteus = gluteus muscle. Original recording parameters matrix 192 x 256, slice thickness 6 mm, a-c field of view (fov) = 380 mm, d-f fov = 180 mm. (a) and (d) Proton density weighting TR = 5000 ms, TE = 12 ms. (b) and (e) Ti-weighting TR = 500 ms, TE = 12 ms. (c) and (f) 7 2-weighting TR = 5000 ms, TE = 100 ms.

Adults The preferred IM injection site is the upper outer quadrant of the buttock (ie, gluteus maximus) or the mid-lateral thigh. 

The administration site is generally the lumbar or quadriceps muscle for rabbits and the gluteus medius muscle for rodents. A control group is given a placebo formulation. A third group may be administered the adjuvant alone. 

The soluble substances, mild irritants and suspensions can be injected by this route in the large skeletal muscles (deltoid, triceps, gluteus maximus, rectus femoris etc.). These muscles are less richly supplied with sensory nerves and are more vascular, so irritant solutions can be injected. Small volumes (up to 2 ml) are injected into the deltoid muscle, and small or large volumes (up to 10 ml) are injected into the gluteal mass. 

Trapezius Deltoid Triceps brachii Teres major Latissimus dorsi Brachioiadialis External oblique Gluteus medius... 

The extent of absorption and tolerability of intramuscular fosphenytoin has been assessed in a double-blind study in which patients received 10 mg/kg dose of intramuscular fosphenytoin in one gluteus muscle and intramuscular saline in the other (65). More than half the patients had serum concentrations in the target range at 30 minutes. There was no pain at either the fosphenjdoin or saline injection sites in 46% of patients and no difference in pain at 60 minutes and thereafter. 

Drugs in aqueous solution are absorbed rapidly following intramuscular (i.m.) injection, although this varies depending on factors such as the blood flow to the injection site. In humans, absorption from the deltoid or vastus lateralis muscles is faster than from the gluteus maximus. Absorption from this site is slower in females than in males. This has been attributed to sex differences in the distribution of subcutaneous fat, since fat is a relatively poorly perfused tissue. 

IM Use 10% (100 mg/ml) clearly identify lidocaine that is for IM use give in deltoid muscle (blood level is significantly higher than if injection is given in gluteus muscle or lateral thigh) Instruct patient that local infiltration may bum and sting briefly... 

Inject IM. Keep into gluteus maximus or lateral aspect of thigh. 

Prepare Decanoate IM injection with 21-gauge needle do not exceed maximum volume of 3 ml per IM site inject slowly, deep IM into upper outer of gluteus maximus... 

Absorption of i.m. administered medications depends on the injection site because perfusion of individual muscle groups differs. For example, drug absorption from the deltoid muscle is faster than that from the vastus lateralis that is more rapid than from the gluteus.In addition, lower perfusion or hemostatic decompensation, frequently observed in ill neonates and young infants, may reduce i.m. absorption. It may also be decreased in neonates who receive a skeletal muscle-paralyzing agent such as pancuronium because of decreased muscle contraction. In addition, the smaller muscle mass of neonates and young infants provide a small absorptive area. 

DF, mice were inoculated with 10 Lewis lung cells into right-hind gluteus muscle. Polymers were administered daily by the intraperitoneal route for 10 consecutive days following tumor implantation. Primary tumor size was determined on day lU (55 inhibition) and increased life span (55 ILS) calculated from mean time to death. 

---