Vastus lateralis muscle

Figure 6. Glycogen content in the vastus lateralis muscle as a function of cycling time at 75-80% of maximal oxygen uptake (VO2 max). Data points are mean values from 10 subjects. For each subject, exercise was performed repeatedly in periods of 15 min separated by 15 min rest periods. At the point of exhaustion and muscle fatigue, muscle glycogen stores were depleted. From Bergstrom and Hultman (1967) with permission from the publisher.

Figure 8. A. Glycogen content in the vastus lateralis muscle after a mixed diet (a) and during 5 days of total starvation ( ) in one subject and eight days of carbohydrate-poor diet (o) followed by a carbohydrate-rich diet ( ) in a second subject. B. Muscle glycogen content before and after exercise. Before exercise the diet was mixed (a) and in the following days was either total starvation ( ) or carbohydrate-poor (o) and finally followed by 1-2 days of a carbohydrate-rich diet ( ). Note the slow rate of glycogen resynthesis when the diet is carbohydrate-poor compared to the rate when the diet is carbohydrate-rich. Redrawn from Hultman and Bergstrom (1967).

Figure 10. The relationship between the initial glycogen content in vastus lateralis muscle and work time in six subjects who cycled to exhaustion at 75% VO2 max. Each subject cycled to exhaustion on three occasions. The first experiment was preceded by a mixed diet (a), the second by a carbohydrate-poor diet (o), and the third by a carbohydrate-rich diet ( ). The energy contents of the diets were identical. In all experiments depletion of the muscle glycogen store coincided with exhaustion and muscle fatigue. From Bergstrom et al. (1967) with permission from the publisher.

Figure 13.23 Depletion of muscle glycogen content during prolonged physical activity. The units of glycogen are xmoLs glucose-equivalent per gram fresh muscle. Glycogen content was measured in biopsy samples taken from the vastus lateralis muscle. Exhaustive physical activity was performed on a bicycle ergometer. Exhaustion coincided with the glycogen content when it was close to zero. (Data from Hermansen et ai, 1967).

J. J. Brault, T. F. Towse, J. M. Slade and R. A. Meyer, Parallel increases in phosphocrea-tine and total creatine in human vastus lateralis muscle during creatine supplementation. Int. J. Sport Nutr. Exerc. Metab., 2007,17,624-634. 

Figure 3. The Influence of exercise duration, during different intensities of treadmill running, on cytochrome c content in the white section of the vastus lateralis muscle (fast-twitch white fibers) of rats. Running speed (O ) 10 m/min, ( ) 20 m/min, ( A) 30 m/min, ( ) 40 m/min, ( ) 50 m/min, (A) 60 m/min, "Reproduced with permission from Ref. 44. Copyright 1982, American Physiological Society. "...

Vastus lateralis muscle from a 48-year-old man with rhabdomyolysis had an increased in vitro response to increasing concentrations of enoximone above 0.6 mmol/1 (10). He also had a heterozygous mutation in his ryanodine receptor gene, with substitution of arginine for glycine in position 2433, a mutation that is associated with malignant hyperthermia. 

Drugs in aqueous solution are absorbed rapidly following intramuscular (i.m.) injection, although this varies depending on factors such as the blood flow to the injection site. In humans, absorption from the deltoid or vastus lateralis muscles is faster than from the gluteus maximus. Absorption from this site is slower in females than in males. This has been attributed to sex differences in the distribution of subcutaneous fat, since fat is a relatively poorly perfused tissue. 

Administer the medication into the vastus lateralis muscle. 

Infants and toddlers should receive intramuscular injections in the vastus lateralis muscle, the large muscle of the thigh. This muscle is large and away from any nerves that could be damaged by the injection. 

The vastus lateralis muscle (lateral side of the thigh) can be used for administering intramuscular injections, but the client often complains that this is more painful than other areas. 

The effects of non-muscular diseases and injury on muscle metabolism have been investigated. Oxidative muscle metabolism has been assessed in people with spinal cord injuries. The rate of PCr resynthesis in right vastus lateralis muscle was measured after electrical stimulation for 60 s at... 

Medial marginal (vertical) fractures in children may traverse the entire thickness of bone or maybe a medial tangential osteochondral fracture. These longitudinal orientated fractures may only be visible on an axial or oblique radiograph. Lateral vertical fractures can occur in athletes due to the pull of the vastus lateralis muscle. 

Intramuscular injections are administered into the deltoid muscle of the upper arm or vastus lateralis muscles in the anterolateral aspect of the middle or upper thigh. 

The technique of inserting the probe in an infant is shown in Figure 4. Except for one patient, the vastus lateralis muscle was used for monitoring in all. To avoid electrical hazards which might be associated with the use of line powered pH meters, a portable battery operated model is always used when patients are being monitored. No wo ind infections have been noted at the probe... 

Maltais F, Sullivan Ml, LeBlanc P, et al. Altered ex H ession of myosin heavy chain in the vastus lateralis muscle in patients with COPD. Eur Respir J 1999 13 850-854. 

Simard C, Maltais F, Le Blanc P, et al. Mitochondrial and capillarity changes in vastus lateralis muscle of COPD patients electron microscopy study. Med Sci Sports Exerc 1996 28 S95. 

Carroll, C.C., Huckey, J.D., Williams, R.H., Sullivan, D.H., andTrappe,T.A., Human soleus and vastus lateralis muscle protein metabolism with an amino acid infusion. Am J Physiol Endocrinol Metab, 288, E479, 2005. 

The vastus medialis and vastus lateralis muscles are respectively located on the medial and lateral sides of the rectus femoris (Figs. 13.1,13.2b,c). Both take their origin from the posterior aspect of the femur (linea aspera) and insert distally into the middle layer of the quadriceps tendon. The proximal tendon of the vastus lateralis is located in close rela-... 

Fig. 13.30a,b Myositis ossificans, a Longitudinal 12-5 MHz US split-screen image obtained over the vastus lateralis muscle in a patient with a previous history of local blunt trauma with b radiographic correlation reveals multiple, irregularly shaped gross calcifications (arrows) within the vastus intermedius muscle. The vastus lateralis (open arrowheads) is displaced superficially by the bulk of the calcifications... 

Figure 13. Representative measurements of heat flow rate (P) on biopsy samples from the vastus lateralis muscle, obtained from one subject before and after medication with propranolol. The sample ampoule was inserted into the microcalorimeter at and taken out at T. = the mean value during the...

In a group of haemodialysis patients, muscle thermogenesis was evaluated by measurement of heat production in skeletal muscle samples [112]. Biopsies were taken from the vastus lateralis muscle by needle technique, using the same amount of muscle for each patient, about 45 mg. Microcalorimetric measurements were made in a perfusion calorimeter of the thermopile heat conduction type, as previously described. Blood samples for measurement of thyroid hormone concentration were collected the morning before dialysis after the patients had been fasting for 12 h. About 40% of the group of haemodialysis patient were found to have decreased muscle heat production... 

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