Glutamate receptors in brain

Schoepp, D. D. Conn, P. J. (1993). Metabotropic glutamate receptors in brain function and pathology. Trends Pharmacol. Sci. 14, 13-20. 

Massicotte,G., 1996, Effect of phosphatidylserine on the binding properties of glutamate receptors in brain sections from adult and neonatal rats. Brain Res. 740 337-345. 

Generation of ROS during activation of glutamate receptors in brain neurons... 

MSG is used to give a meaty, savory, or brothy taste to foods by stimulating the glutamate receptors on the tongue. There are glutamate receptors in other parts of the body, notably the brain, where glutamate is a neurotransmitter. 

Bergersen, L., Waerhaug, O., Helm, J. et al. A novel postsyn-aptic density protein the monocarboxylate transporter MCT2 is co-localized with delta-glutamate receptors in postsynaptic densities of parallel fiber-Purkinje cell synapses. Exp. Brain Res. 136 523-34,2001. 

Carlton SM, CoggeshaU RE (1999) Inflammation-induced changes in peripheral glutamate receptor populations. Brain Res 820 63-70... 

Geurts JJG, Wolswijk G, Bo L, van der Valk P, et al (2003) Altered expression patterns of group I and II metabotropic glutamate receptors in multiple sclerosis. Brain 126 1755-1766... 

Pin JP, Parmentier ML, Joly C, et al (1998) Coupling of metabotropic glutamate receptors to G-proteins differences from and similarities with other G-protein-coupled receptors. In Moroni F, Nicoletti F, PeUegrini-Giampietro DE (eds) Metabotropic glutamate receptors and brain function. Portland Press, Colchester, pp 9-18 Pitsikas N, BrambiUa A, Besozzi C, et al (2001) Effects of cerestat and NBQX on functional and morphological outcomes in rat focal cerebral ischemia. Pharmacol Biochem Behav 68 443-447... 

Ampakines are drugs that potentiate currents mediated by AMPA-type glutamate receptors. In behavioral tests, ampakines are effective in correcting behaviors in various animal models of schizophrenia and depression. They protect neurons against neurotoxic insults, in part by mobilizing growth factors such as brain-derived neurotrophic factor (BDNF). 

Mao L, Wang JQ (2001) Upregulation of preprodynorphin and preproenkephalin mRNA expression by selective activation of group I metabotropic glutamate receptors in characterized primary cultures of rat striatal neurons. Brain Res Mol Brain Res 86 125-137. 

Daniel H, Crepel F (2001) Control of Ca(2+) influx by cannabinoid and metabotropic glutamate receptors in rat cerebellar cortex requires K(+) channels. J Physiol 537(Pt 3) 793-800 Davis MI, Ronesi J, Lovinger DM (2003) A predominant role for inhibition of the adenylate cy-clase/protein kinase A pathway in ERK activation by cannabinoid receptor 1 in N1E-115 neuroblastoma cells. J Biol Chem 278(49) 48973-80 Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, Gibson D, Mandelbaum A, Etinger A, Mechoulam R (1992) Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258 1946-9... 

---