AMPA-type glutamate receptors

Kamiya Y, Andoh T, Furuya R, et al Comparison of the effects of convulsant and depressant barbiturate stereoisomers on AMPA-type glutamate receptors. Anesthesiology 90 1704-1713, 1999... 

Ampakines are drugs that potentiate currents mediated by AMPA-type glutamate receptors. In behavioral tests, ampakines are effective in correcting behaviors in various animal models of schizophrenia and depression. They protect neurons against neurotoxic insults, in part by mobilizing growth factors such as brain-derived neurotrophic factor (BDNF). 

Nicoll R. A., Tomita S., and Bredt D. S. (2006). Auxiliary subunits assist AMPA-type glutamate receptors. Science 311 1253-1256. 

Bernard V, Somogyi P, Bolam JP. Cellular, subcellular, and subsynaptic distribution of AMPA-type glutamate receptor subunits in the neostriatum of the rat. J Neurosci 1997 17 819-833. 

Suzuki T, Ito J, Takagi H, Saitoh F, Nawa H, et al. 2001. Biochemical evidence for localization of AMPA-type glutamate receptor subunits in the dendritic raft. Brain Res Mol Brain Res 89 20-28. 

Nakazawa, K., Mikawa, S., Hashikawa, T., and Ito, M. (1995). Transient and persistent phosphorylation of AMPA-type glutamate receptor subunits in cerebellar Purkinje... 

Tan, S. E., Wenthold, R. J., and Soderling, T. R. (1994). Phosphorylation of AMPA-type glutamate receptors by Ga" /calmodulin-dependent protein kinase II and PKG in cultured hippocampal neurons./. Neurosci. 14, 1123-1129. 

Baude A, Nusser Z, Molnar E, Mcllhinney RA, Somogyi P (1995) High-resolution immunogold localization of AMPA type glutamate receptor subunits at synaptic and non-synaptic sites in rat hippocampus. Neuroscience 69 1031-1055... 

Retinal ganglion cells are the output cells of the refina. Their axons course along the vitreal surface of the refina and bundle together to exit the eye as the optic nerve. Ganglion cells are excited by glutamate released from bipolar cells acting on both NMDA and non-NMDA (KA- and AMPA-type) glutamate receptors (Thoreson and Witkovsky, 1999). 

Perez, J.L., Khatri, L., Chang, C., Srivastava, S., Osten, P., Ziff, E.B. PICK1 targets activated protein kinase calpha to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2. J. Neurosci. 2001, 21, 5417-28. 

Jonas P, Racca C, Sakmann B, Seeburg PH, Monyer H (1994) Differences in Ca " permeability of AMPA-type glutamate receptor channels in neocortical neurons caused by differential GluR-B subunit expression. Neuron 72 1281-1289. 

Wang Y-X, Wenthold RJ, Ottersen OP, Petralia RS (1998) Endbulb synapses in the anteroventral cochlear nucleus express a specific subset of AMPA-type glutamate receptor subunits. J Neurosci /S l 148-1160. 

Reng D, Hack I, Muller M, Smolders JW (1999) AMPA-type glutamate receptor subunits are expressed in the avian cochlear hair cells and ganglion cells. Neuroreport 70 2137-2141. 

The function of AMPA-type glutamate receptors (Akinshola et al. 1999) and nicotinic acetylcholine receptors (Oz et al. 2003), expressed in oocytes, was inhibited by anandamide. These effects are, again, CBi and CB2 receptor-independent. 

Lovinger, D.M. (1993) High ethanol sensitivity of recombinant AMPA-type glutamate receptors expressed in mammalian cells. Neurosci. Lett. 159, 83-87. 

Limatola, C., Ciotti, M. T., Mercanti, D., Santoni, A., and Eusebi, F. (2002). Signaling pathways activated by chemokine receptor CXCR2 and AMPA-type glutamate receptors and involvement in granule cells survival. J. Neuroimmunol. 123, 9-17. 

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