Glucose measurement

Two or more linked enzyme reactions can lead to a change in the concentration of NADH or NADPH that is equivalent to the concentration of the original analyte. The reference glucose measurement using hexokinase [9001-51-8] and glucose-6-phosphate dehydrogenase [9001-40-5] is an example ... 

Fig. 4. Dose response for blood glucose measurement using a dry chemistry system having a water-borne, tough coating film. The numbers represent...

Peterson J.I., Goldstein S.R., A miniature fiberoptic pH sensor potentially suitable for glucose measurements, Diabetes Care 1982 5, 272. 

Bantle J.P., Thomas W., Glucose measurement in patients with diabetes mellitus with dermal interstitial fluid, J.Lab. Clin. Med. 1997 130 436-441. 

J. Wang and X. Zhang, Screen printed cupric-hexacyanoferrate modified carbon enzyme electrode for single-use glucose measurements. Anal. Lett. 32, 1739-1749 (1999). 

Postprandial glucose measurements should be made 1-2 hours after the beginning of the meal, generally the time of peak levels in patients with diabetes. 

Noninvasive glucose measurements can potentially be performed with phase-modulation fluorometry. The blood gas application described above requires drawing the blood, i.e., an invasive as well as an unpleasant procedure. Similarly, present measurements of blood glucose also require fresh blood. Insulin-dependent diabetics... 

Much effort has been expended for some method of online glucose measurement however, to date there is no real sign of an effective device. Several earlier studies utilized a glucose-permeable membrane with glucose oxidase immobilized and fol-... 

McNay EC, Sherwin RS. 2004. From artificial cerebro-spinal fluid (acsf) to artificial extracellular fluid (aecf) microdialysis perfusate composition effects on in vivo brain ecf glucose measurements. J Neurosci Methods 132(1) 35-43. 

Massachusetts Instimte of Technology, Raman spectroscopy for non-invasive glucose measurements. Inventors ... 

One question that is often asked of statisticians is in what sense can we be 95% confident that the population mean lies within the limits 3.84 and 4.13 To answer the question we can again conduct a sampling experiment as follows. Suppose that the 40 blood glucose measurements in Figure 8.3 comprised the total population of values. For random sample of size 10 from the populations of blood glucose values determine the sample mean, standard error and the corresponding 95% confidence interval. Repeat the process 100 times. The results of such an experiment are shown in Figure 8.6. 

Drug/Lab fesf/nteracf/ons Acetaminophen may interfere with Chemstrip bG, Dextrostix, and Visidex II home blood glucose measurement systems decreases of > 20% in mean glucose values may be noted. This effect appears to be drug-, concentration-, and system-dependent. 

Desirable supplemental tests include measurement of bilirubin, amylase and serum lipids. Regular serum glucose measurements are desirable when Pis are used. 

Biosensors constructed for ethanol and D-glucose measurements in beverages were built using ferrocene compounds as electron transfer mediators between the coenzyme PQQ of immobilized enzymes glucose (GDH) and alcohol (ADH) dehydrogenases and a carbon electrode surface <2003JOM(668)83>. 

During purification procedures cellobiase activity was monitored by measuring nitrophenol (at A42onm) release for p-nitrophenyl-/ -D-glucoside (JO). Kinetic studies and enzyme characterization were carried out using / -D-cellobiose as substrate with the product, glucose, measured with a Beckman Glucose Analyzer (JO). Assay conditions were pH 4.8 and 50°C. 

Problems with the use of blood glucose measurement systems are reported from time to time. For example, it is easy to read glucose meters wrongly (SEDA-25, 508). Hypoglycemia was missed when a patient inadvertently switched the glucose meter from mmol/1 to mg/dl and read 266 mg/dl as 26.6 mmol/1 and 158 mg/dl as 15.8 mmol/1 (302). 

Steward DE, Khardori R. An avoidable cause of false home glucose measurements. Diabetes Care 2001 24(4) 794. 

G. Palleschi, M.A. Nabi Rahni, G.J. Lubrano, J.N. Nwainbi and G.G. Guilbault, A study of interferences in glucose measurements in blood by hydrogen peroxide based glucose probes, Anal. Biochem., 159 (1986) 114-121. 

C. Tollnick and M. Beuse, On-line glucose measurements in industrial bioprocess engineering, 2005. www.trace.de/en/onlinemessung/glucose. htm... 

Lee, S., et al. 2005. Glucose measurements with sensors and ultrasound. Ultrasound Med Biol 31 971. 

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