Gelatin mannitol

Klonopin Wafers Clonazepam 0.125, 0.25,0.5, 1 mg Orally disinte- grating tablet Panic disorder Gamma aminobutyric acid (GABA) enhancement Gelatin, mannitol, methylparaben sodium, propylparaben sodium, xanthan gum Roche... 

Cardinal Health) Reditab acid, gelatin, mannitol, mint flavor drying... 

Excipients used in the formulation usually include a mixture of a water-soluble polymer and a crystalline sugar. Mannitol and natural polysaccharides such as gelatin and alginates are used. Microencapsulation and complexation with ion exchange resins can be combined with additional flavors and sweeteners for taste masking of bitter drugs. The fairly complex nature of manufacture and scale-up contributes to... 

Immediate-release formulations typically consist of the drug substance, fillers such as mannitol and lactose and binders such as gelatin, gelatin hydrolysates, and polyvinylpyrolidone. Cross-linked biopolymers based on collagen derivatives are used for sustained-release pellets. See Refs. ° for a detailed discussion on the formulation and processing variables. 

Mannitol has also been used to prevent thickening in aqueous antacid suspensions of aluminum hydroxide (<7% w/v). It has been suggested as a plasticizer in soft-gelatin capsules, as a component of sustained-release tablet formula-tions, and as a carrier in dry powder inhalers. It is also used as a diluent in rapidly dispersing oral dosage forms. 

Each vial contains imiglucerase (212 units), mannitol (170 mg), sodium citrates (70 mg), trisodium citrate (52 mg), disodium hydrogen citrate (18 mg), polysorbate 80 (0.53 mg). Citric acid and/or sodium hydroxide may have been added at the time of manufacture to adjust pH. Haemaccel (cross-linked gelatin polypeptides) is used as a stabilizing agent. 

Leuprolide acetate IM (microsphere suspension) After reconstitution 0.13% Gelatin 6.6% dl-Lactic and glycolic acid copolymer 13% Mannitol 0.2% Polysorbate 80 1% Carboxymethylcellulose in WFI... 

Stabilization of an antacid prepn comg gelatinous aluminum hydroxide with a hexitol (sorbitol or mannitol) Alford,... 

Uncoated tablet materials, lactose, liquid glucose, mannitol, stearic acid, starch, calcium stearate, talc and sucrose could be tolerated in the precipitation solution without interference. As gelatin and polyvinylpyrrolidone precipitate with sodium tetraphenylboron it is not possible to apply the method to tablets containing these materials. 

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