Collagen derivatives

This consists of absorbable strands of collagen derived fiom mammahan tissue, particularly the intestine of sheep. Because of its source, it is particularly prone to bacterial contamination, and even anaerobic spores may be found in such material. 

Tomee JF, Kauffman HF, Klimp AH, de Monchy JGR, Koeter GH, Dubois AEJ Immunologic significance of a collagen-derived culture filtrate containing proteolytic activity in Aspergillus-related diseases. J Allergy Clin Immunol 1994 93 768-778. 

Grab B, Miles AJ, Furcht LT, Fields GB Promotion of fibroblast adhesion by triple-helical peptide models of type I collagen-derived sequences. J Biol Chem 271 12234-12240,1996... 

Immediate-release formulations typically consist of the drug substance, fillers such as mannitol and lactose and binders such as gelatin, gelatin hydrolysates, and polyvinylpyrolidone. Cross-linked biopolymers based on collagen derivatives are used for sustained-release pellets. See Refs. ° for a detailed discussion on the formulation and processing variables. 

Colla-Moist. [Brooks Industries] Collagen derivs. moisturizing protein complexes for cosmetics. 

Foam-CoU. [Brodcs Industries] Collagen derivs. foaming proteins for skin and hair care cosmedcs. 

Granpra [Grant Industries] Hydrolyzed collagen derivs. ... 

Lamepon . [Henkel/Cospha Henkel Canada Henkel KGaA] Hydrolyzed collagen derivs. mild surfactant, dispersant, wetting agent, stabilizo-, protective colloid, detergent for personal care prods., dyestuffs. 

Lecein . [Inolex] Collagen derivs. filmforming protein, hair fixative, conditioner, hair spray resin plasticiEer to hair prq ., makeup, skin care prods. 

Pro-Tein. [Maybrodt] Hydrolyzed collagen derivs. cationic substantivity agent, anti-irritant for hair prods., facial (oners, antqmpinmts, after shaves. 

Solu-CoU. [Brocdcs Industries] Collagen derivs. or blends to hair arid skin care cosmetics. 

Polymeric collagen peptides should be somewhat substantive to hair because they contain multiple ionic and polar sites for bonding, in addition to offering large molecular surfaces with many sites for Van der Waals bonding. Methionine, tyrosine [46], and tryptophan [47] are monomeric species of proteins, and they have been shown to sorb onto hair from aqueous solution. Collagen-derived polypeptides, or polymers of amino acids, have also been shown to have an affinity for hair [48-50], and one would predict that they should be more substantive to hair than their monomers. 

The desorptive action of surfactants and salts on polypeptides already sorbed to hair has not been examined as fully as for polymer JR. On the basis of theory, one would not expect collagen-derived polypeptides to be as substantive to hair as a high-charge-density cationic polymer. 

M. Deng, et al.. Cellulose and collagen derived micro-nano structured scaffolds for bone tissue engineering, J. Biomed. Nanotech-nol. 9 (2013) 719-731. 

CAS 9000-70-8 EINECS/ELINCS 232-554-6 Synonyms Gelatine Gelatins White gelatin Definition Complex combination of proteins obtained from partial hydrolysis of collagen derived from animal skin, connective tissues, and bones Type A is derived from acid-treated precursor. Type B from alkali-treated precursor... 

Self-assemhly/physical cross-finking of polypeptides (e.g., triple-helix formation hy collagen-derived tripeptides or self-assembly to fibers through silk-derived p-sheet-forming domains)... 

H) Collagen derived from the same species as recipient Tissues derived from the same species, for example, tissue grafts for medical use derived from human cadaveric donors, are referred to as allografts. These tissues constitute a plentiful source of stmctural materials for use in surgical repair of the musculoskeletal system. In contrast to vital organs for transplantation that are utilized without modification, stmctural tissues such as bone and soft connective tissues must be processed to remove blood, cells, soluble proteins, and enzymes before they can be used in vivo. Allografts retain many of their intrinsic stmctural and biomechanical properties. 

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