Food-medication interactions

Food-medication interaction Determine if food interacts with medication. A food-drug interaction may result in an adverse effect. At times, medication is taken with food to reduce an upsetting side effect of the medication. On the other hand, food can slow absorption for some medications. 

The above illustration should be a clear caution that components of food may interact with drugs, resulting in substantial positive or negative therapeutic effects. As will be noted later, this principle also applies to so-called dietary supplements, including bo-tanicals, used for the treatment of numerous medical conditions. 

Certain t) es of foods can adversely effect the dmg s therapeutic effect by increasing absorption, delaying absorption, and even preventing absorption of the medication. Furthermore, food may cause the patient to experience an adverse reaction as in the case with phenelzine sulfate (Nardil), which is an MAO monoamineoxidase inhibitor anti-depressant. Nardil caimot be given with foods that use bacteria or molds in their preparation or for preservation of those that contain tyramine, such as cheese, sour cream, beer, wine, figs, raisins, bananas, avocados, etc. The nurse must assess if the dmg has a contraindication with food and educate the patient about this food-dmg interaction. 

Selected food hypersensitivity and medication interaction mainly due to one or more excipients may also preclude use of certain medications as listed in Table 4.3. 

In deciding whether disulfiram should be used in alcoholism rehabilitation, patients should be made aware of the hazards of the medication, including the need to avoid over-the-counter preparations that include alcohol, the need to avoid drugs that can interact with disulfiram, and the potential for a DER to be precipitated by alcohol used in food preparation. The administration of disulfiram to anyone who does not agree to use it, who does not seek to be abstinent from alcohol, or who has any psychological or medical contraindications is not recommended. 

What prescription and over-the-counter medications should be avoided to prevent drug-drug, drug-food, or drug-disease interactions ... 

In this chapter we will consider the following as examples of radiation chemical applications (1) dosimetry, (2) industrial synthesis and processing, (3) irradiation of food, waste, and medical equipment, and (4) low-energy ion interaction with matter. Dosimetry is of fundamental importance for yield calculations and also for personnel exposure. Industrial processing would include... 

Adsorption of (bio)polymers occurs ubiquitously, and among the biopolymers, proteins are most surface active. Wherever and whenever a protein-containing (aqueous) solution is exposed to a (solid) surface, it results in the spontaneous accumulation of protein molecules at the solid-water interface, thereby altering the characteristics of the sorbent surface and, in most cases, of the protein molecules as well (Malmsten 2003). Therefore, the interaction between proteins and interfaces attracts attention from a wide variety of disciplines, ranging from environmental sciences to food processing and medical sciences. 

Abstract Why do patients refer to medications as the little white pill or the pink capsule Strange or confusing names are problematic especially if you are old and have many medications. Other potential practical medication problems in the elderly including problems to remember, to swallow, practical handling, food- and drug-interactions, short use-before date are listed and described in this chapter. Possible solutions are also presented. For patient safety and for cost-effective care it s very important to identify and solve these problems for the individual patient. A systematic model for this is presented in Chapter 10. 

Keywords Practical problems Generic drug Analogue drug Medication intake Food interactions... 

Combine it with a daily routine like when waking up, at breakfast, to the 9 o clock news etcetera. Food interactions must be considered (below) Reduce the number of daily intake. Use Depot preparations or medications with longer half-life. 

Determine the drug interaction potential when concurrent medications are administered, as well as food interaction, assess the enzyme induction potential, and assess the need for therapeutic drug monitoring during efficacy testing. 

Immunosensors have been developed commercially mostly for medical purposes but would appear to have considerable potential for food analysis. The Pharmacia company has developed an optical biosensor, which is a fully automated continuous-flow system which exploits the phenomenon of surface plasmon resonance (SPR) to detect and measure biomolecular interactions. The technique has been validated for determination of folic acid and biotin in fortified foods (Indyk, 2000 Bostrom and Lindeberg, 2000), and more recently for vitamin Bi2. This type of technique has great potential for application to a wide range of food additives but its advance will be linked to the availability of specific antibodies or other receptors for the various additives. It should be possible to analyse a whole range of additives by multi-channel continuous flow systems with further miniaturisation. 

More concerning are the less common but potentially dangerous interactions of the MAOis with certain foods and medications. Because the MAOis permanently disable the MAO enzymes (until the body is able over the course of several weeks to produce a new supply of the enzymes), taking a medication or eating a food that contains one of the substances eliminated by the MAO enzymes can cause toxic accumulation. The result is a so-called hypertensive crisis in which the blood pressure is uncontrollably elevated, risking heart attack, stroke, or death. 

Althongh the MAOis are highly effective, their usefulness is limited by their potential for dangerons interactions with certain medications and foods. Please refer to Chapter 3 for a more complete discnssion of MAOis. 

When treating APD, MAOIs are used in doses similar to those used to treat depression. The primary limitation of the MAOIs is their potential to interact dangerously with certain foods and other medications. This limits their usage in many illnesses, but they remain a viable option for patients who have failed other treatments and can tolerate the life-style changes mandated by taking a MAOI. Please refer to Chapter 3 for more information regarding the MAOIs. 

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