Filling Procedures

Depending on the growing system chosen, the compost is loaded into trays, shelves or a bulk 

Compress a long strawy compost and fill loosely a short dense compost. 

Ifthe compost appears dry, water lightly and evenly during filling. If water streams out when a handful is squeezed, don t fill. Add again as much gypsum, turn and wait a few days, 

Fill all shelves and trays evenly and to the same depth. Avoid creating pockets of compact compost. Keep all compost within the container. No compost should hang over the sides. 

Once finished, the floor should be cleaned of all loose compost, then washed with water. 

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Specialty Gases. The purity of specialty gases depends on the systems and procedures adopted by the distributors for bulk gas supply and cylinder preparation, filling, and deHvery. The distributors need to foUow strict cylinder selection, preparation, and filling procedures to ensure the quaHty of the products. Most of the precautions taken into consideration in the bulk gases deHvery system are also appHed for specialty gases to eliminate recontamination. 

As the production methods of MWCNTs is very efficient [8] (see Chaps. 2 and 12), it is an advantage to implement a filling procedure after the synthesis. A promising approach to fill CNT cavities, could exploit the capillary properties that have been revealed by Ajayan and lijima [9]. Subsequent studies by Dujardin et al.[10] allowed the estimations of a surface tension threshold in order to select materials that are good candidates to wet and fill CNTs. 

Sequence for Metallic Lacquers The sequence when producing normal metallic lacquers differs from the sequence when producing uni lacquers to the extent that in this case no pre-dispersion or dispersion has to take place. The production sequence is the same as the production sequence when producing uni lacquers beginning with the dose spinners until the filling procedure (see Figures 4.6 and 4.7). 

The filling procedure automatically follows three steps (for the example of a filling station for vehicle tanks with 35 MPa) ... 

Fig. 9.3 Families of methods for creating C3 materials. The differences relate to the source of the binder carbon and to the method of application. The dashed lines indicate that in these processes repetitive graphitization and filling procedures can be applied to improve the density and homogeneity of the final material. Such repetitive procedures are not necessary when a continuous supply of the carbon source is applied as in the CVD procedures. The shaded processes are mainly applied in large-scale productions of C3 materials.

CPG was dry packed into stainless steel columns using the tap-fill procedure (20). Column dimensions were 100 cm x 4.6 mm ID for the 1000, 1400, 2000 and 3000A material and 50 cm x 4.6 mm ID for the 75A packing. A description of these packings is given in Table I. Values listed in the table were obtained from the manufacturer (Blectronucleonics Inc.). 

Particle Contamination of Ampules and Vials during Filling Procedure... 

To describe the media fill procedure to qualify the aseptic following lines... 

This procedure describes methods and procedures for the conduct of process simulation tests of sterile products, including media fill procedures, media selection, fill volume, incubation, time and temperature, inspection of filled volume, documentation, interpretation of results, and possible corrective action required where its main purposes are to... 

In the second edition, 64 new validation SOPs are added to describe documentation required for sterility assurance, qualification and requalification template reports of major sterile equipments, critical applicable procedures, templates for certification guidelines, media fill procedures, environmental control guidelines, training, and critical environmental performance evaluation procedures. 

The x-ray powder diffraction pattern of etodolac was obtained using a Rigaku MiniFlex powder diffraction system, equipped with a horizontal goniometer in the 0 /2-0 mode. The x-ray source was nickel-filtered K-a emission of copper (1.544056 A). A 10-mg sample was packed into an aluminum holder using a back-fill procedure, and was scanned over the range of 50 to 6 degrees 2-0, at a scan rate of 0.5 degrees 2-0/min. 

Low-fat spreads with 40% fat content and containing protein usually have a shelf life of 8-10 weeks and water-based low-fat spreads of about 4 months based on storage at temperatures below 10°C (50°F) (90) (see Section 5.1). Very low fat spreads with fat contents below 20% and with a water continuous emulsion character require low pH, ultra high temperature processing, and possibly aseptic filling procedures to allow closed shelf lives comparable to conventional low-fat spreads (91). 

Unit-dose and bi-dose systems are designed to deliver one or two doses into the nostril(s) (Fig. 9). As compared to multidose pump systems, unit-dose and bi-dose systems are distinguished by a different actuation principle. The dose volume is predetermined by the prefilled glass vial and sealed with a rubber stopper. The glass and rubber are the identical materials used in syringes. The benefit is an optimal protection against environmental influences. Unif-dose and bidose systems can be sterilized, and an aseptic filling procedure justifies the omission of preservatives. 

In the manufacture of MDIs, liquid filling procedures have been developed based on either a cold-filling method or a pressure-filling method. Both methods are suitable for either solution or suspension formulations and regardless of the process, it is important to maintain a low atmospheric relative humidity in the filling area to minimize condensation and possible absorption of water by the product. 

The characterization of the total mass thus obtained, performed on representative samples taken during the vial filling procedure, gave additional information on the properties of the material. The average moisture content, measured by Karl-Fisher titration, was lower than 3%. The particle size distribution of the whole mass, measured using the Sympatec analyzer with Helos measuring device, was to peak at 80-90 pm with an upper limit of 435 pm. 

During the filling procedure and for each bottled batch a sample should be set aside for the later verification of the homogeneity. 

Fig. 4.10b. Two stage nested design of an interlaboratory study allowing the verification of the homogeneity of the RM. (L laboratory number 1 to i, S sample bottle number 1 or 2 of laboratory i, X test sample of bottle 1 or 2 of laboratory i). In total 2i bottles are used, and in total 4i measurements are performed. If the tested bottles are selected regularly during the filling procedure, a good estimate of the between-bottle homogeneity can be given.

The water mass fraction of the milk powder was determined on 18 samples regularly taken during the filling procedure and was measured by Karl-Fischer titration the water content was found to be (2.1 0.2)% (mass fraction). 

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