Fever subcutaneous

N, nausea D, diarrhea HA, headache SOB, shortness of breath HTN, hypertension LFTs, liver function tests CBC, complete blood count ISR, injection-site reactions IR, infusion reactions IV, intravenous MYL, myelosuppression (watch for fever, symptoms of infection, easy bruisability, and bleeding) SC, subcutaneous. 

Signs and Symptoms Causes fever, labored breathing with increased respiratory rate, and depression. There may be paroxysmal coughing. May cause conjunctivitis, subcutaneous edema of the head, neck, brisket, thorax, and ventral abdomen. There may be edema in the supraorbital fossa above the eye. 

In an infected open wound scenario, the infection spreads in 1 to 3 days from an original contaminated wound site into the subcutaneous tissue and muscle. The result is a foul-smelling discharge progressing to necrosis and fever. Toxemia, shock, and death may follow. With a naturally-occurring food-borne illness, a... 

Flulike symptoms, including fever, chills, weakness, fatigue, myalgia, and arthralgia, are the most common side effects of interferon therapy. These symptoms occur in more than 50% of patients given injections of interferons either intravenously, intramuscularly, or subcutaneously. Intralesional injection may produce milder flulike symptoms with somewhat less frequency. Tolerance to these symptoms generally develops with repeated dosing. 

The filarial worms differ from other nematodes in that they are threadlike and are found in blood and tissue. The infective larvae enter following the bite of an infected arthropod (fly or mosquito). They then enter the lymphatics and lymph nodes. Fever, lymphangitis, and lymphadenitis are associated with the early stage of the disease. Chronic infections may be characterized by elephantiasis as a result of lymphatic obstruction. Some species of filarial worms migrate in the subcutaneous tissues and produce nodules and blindness (onchocerciasis). 

Yellow fever Live virus Subcutaneous One dose 10 days to 10 years before travel and booster at every 10 yrs. 

This formula expels wind and eliminates dampness from the superficial part of the body and the subcutaneous region. It treats wind-dampness at the superficial level of the body and the Qi movement and blood circulation are blocked. This disorder is manifested as stiffness and pain of the neck, back and shoulders, headache, heaviness of the body, aversion to cold with mild fever, a white, slightly sticky tongue coating and a superficial pulse. 

Recombinant human IL-11 (oprelvekin) is a polypeptide of 177 amino acids. It differs from natural IL-11 due to lack of glycosylation and the amino-terminal proline residue. Oprelvekin is administered by subcutaneous injection, usually 6-24 h after chemotherapy, at a dose of 25-50 p,g/kg per day. The drug has a half-life of about 7h. It is used to stimulate bone marrow to induce platelet production in nonmyeloid malignancies in patients undergoing chemotherapy. The common side effects of oprelvekin include fluid retention, tachycardia, edema, nausea, vomiting, diarrhea, shortness of breath and mouth sores. Other side effects include rash at the injection site, blurred vision, paresthesias, headache, fever, cough and bone pain. Rarely, CLS may occur. 

Efalizumab is administered weekly by subcutaneous injections to treat psoriasis, where a steady state is reached after 4 weeks. Its side effects include serious infections, thrombocytopenia, hemolytic anemia and the probability of malignancies due to its immunosuppressive effects. Other common side effects produced by efalizumab within 2 weeks of administration are nausea, fever, chills and headache. Furthermore, it can produce symptoms associated with hypersensitivity reaction. 

Most cytokines (including TNF-o-, IFN-r, IL-2, G-CSF (filgrastim), and GM-CSF) have very short serum half-lives (minutes). The usual subcutaneous route of administration provides slower release into the circulation. Each cytokine has its own unique toxicity, but some toxicities are shared. Thus, IFN-n, IFN-B, IFN-r, IL-2, and TNF- all induce fever, flu-like symptoms, anorexia, fatigue, and malaise. 

Cellulitis is a skin infection of the dermis and subcutaneous tissues. It is characterised by redness, swelling, pain and inflammation. A common symptom is fever. Cellulitis is caused by bacterial infection, most commonly Streptococcus (group A) and Staphylococcus. 

SAFETY PROFILE Moderately toxic by subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects in infants by intramuscular route dermatitis and fever. When heated to decomposition it emits acrid smoke and fumes. See also CALCIUM COMPOUNDS. 

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