Experiences in Groups

Because the major causes of blast generation in vapor cloud explosions are reasonably well understood today, we can approach the overview of experimental research more systematically by treating and interpreting the experiments in groups of roughly similar arrangements. Furthermore, some attention is given to experimental research into the conditions necessary for direct initiation of a detonation of a vapor cloud and the conditions necessary to sustain such a detonation. 

In the classical statistical literature, one of the two qualitative factors is referred to as the treatments and the other qualitative factor is referred to as the blocks . Hence, the term block designs . In some studies, one of the qualitative factors might be correlated with time, or might even be the factor time itself by carrying out the complete set of experiments in groups (or blocks ) based on this factor, estimated time effects can be removed and the treatment effects can be revealed... 

Accepting the facts that the conventional expository laboratory has many problems associated with it, as well as that it is not an easy task to replace it entirely with inquiry-type practical work, Tsaparlis and Gorezi (141) proposed a modification of a conventional, one-semester, expository physical chemistry laboratory to accommodate a project-based component. Eight project-type tasks were used, mostly taken from articles in the Journal of Chemical Education, which is a rich source. The conventional experiments remained intact in this approach, being simply enriched with the project-based component. Students working cooperatively carried out both the conventional and the project parts in pairs for the conventional experiments, in groups of four for the project work. 

Inspection of the calculations in Table 6 shows that the estimate s(H) is determined almost entirely by the results of group 1 (runs 1, 2 and 3). Furthermore, j(JE) is considerably greater than the standard error of any individual rate coefficient estimated from the scatter of the experimental values of In a about the fitted straight line. In other words, it is the inability to replicate the experimental conditions exactly rather than the definition of the straight lines which determines the precision of the final estimate of the rate coefficient. In fact, we show in the calculations set out in Table 7 that the replicate experiments in Group 1 differ significantly from one another. It is because these results are so discordant that we have... 

As shown above, the whole set comprises three groups in group 1, there are 3 experiments, in group 2, 2 experiments and group 3, 1 experiment therefore, ri = 3, ri = 2 and r, = 1. The object is to calculate... 

Once a design has been established, one has to consider in what order to perform the experimental runs. The natural tendency is to reduce costs by running experiments in groups that... 

Cf, Wilfred Bion s pairing culture/ as described in his book Experiences in Groups, London, Tavistock, 1961. 

Bion, W. (1961). Experiences in Groups. New York Basic Books. 

Geometry From Africa Mathematical and Educational Explorations, Paulus Gerdes Identification Numbers and Check Digit Schemes, Joseph Kiitland Interdisciplinary Lively Application Projects, edited by Chris Amey Laboratory Experiences in Group Theory, Ellen Maycock Parker Learn from the Masters, Frank Swetz, John Fauvel, Otto Bekken, Bengt Johansson, and Victor Katz... 

Patel, U. R. 2007. Experiments in group decision making in the analytic hierarchy process. MS Thesis, Department of Industrial Engineering, The Pennsylvania State University, University Park, PA. 

The polarizability of T1 and element 113 has been calculated using the fully relativistic ab initio Dirac-Coulomb Fock-space coupled-cluster method and the finite field procedure. For Tl, the theoretical value is in good agreement with experiment. In group 13, the atomic polarizability increases from A1 to Ga, attains a maximum for In and then decreases towards Tl and furthermore towards element 113. So, element 113 presents the smallest polarizability, which results from the large relativistic contraction and stabilization of the 7pi/2 orbital. These values have then been used to estimate the adsorption enthalpies of Tl and element 113 on polyethylene and teflon surfaces and have shown that the difference of enthalpy attains 6 kJ/mol, which should be enough to separate and identify them. 

In 1973, a group of Russian experimenters may have produced metallic hydrogen at a pressure of 2.8 Mbar. At the transition the density changed from 1.08 to 1.3 g/cms. Earlier, in 1972, at Livermore, California, a group also reported on a similar experiment in which they observed a pressure-volume point centered at 2 Mbar. Predictions say that metallic hydrogen may be metastable others have predicted it would be a superconductor at room temperature. 

The following experiments may he used to illustrate the application of titrimetry to quantitative, qtmlitative, or characterization problems. Experiments are grouped into four categories based on the type of reaction (acid-base, complexation, redox, and precipitation). A brief description is included with each experiment providing details such as the type of sample analyzed, the method for locating end points, or the analysis of data. Additional experiments emphasizing potentiometric electrodes are found in Chapter 11. 

The terminal groups of a polymer chain are different in some way from the repeat units that characterize the rest of the molecule. If some technique of analytical chemistry can be applied to determine the number of these end groups in a polymer sample, then the average molecular weight of the polymer is readily evaluated. In essence, the concept is no different than the equivalent procedure applied to low molecular weight compounds. The latter is often included as an experiment in general chemistry laboratory classes. The following steps outline the experimental and computational essence of this procedure ... 

The total electron density contributed by all the electrons in any molecule is a property that can be visualized and it is possible to imagine an experiment in which it could be observed. It is when we try to break down this electron density into a contribution from each electron that problems arise. The methods employing hybrid orbitals or equivalent orbitals are useful in certain circumsfances such as in rationalizing properties of a localized part of fhe molecule. Flowever, fhe promotion of an electron from one orbifal fo anofher, in an electronic transition, or the complete removal of it, in an ionization process, both obey symmetry selection mles. For this reason the orbitals used to describe the difference befween eifher fwo electronic states of the molecule or an electronic state of the molecule and an electronic state of the positive ion must be MOs which belong to symmetry species of the point group to which the molecule belongs. Such orbitals are called symmetry orbitals and are the only type we shall consider here. 

Historically, the discovery of one effective herbicide has led quickly to the preparation and screening of a family of imitative chemicals (3). Herbicide developers have traditionally used combinations of experience, art-based approaches, and intuitive appHcations of classical stmcture—activity relationships to imitate, increase, or make more selective the activity of the parent compound. This trial-and-error process depends on the costs and availabiUties of appropriate starting materials, ease of synthesis of usually inactive intermediates, and alterations of parent compound chemical properties by stepwise addition of substituents that have been effective in the development of other pesticides, eg, halogens or substituted amino groups. The reason a particular imitative compound works is seldom understood, and other pesticidal appHcations are not readily predictable. Novices in this traditional, quite random, process requite several years of training and experience in order to function productively. 

Direct proof of an oxaziridine intermediate was achieved in photolysis experiments in an organic glass at 77 K (80JA5643). Oxaziridine (75), formed by photolysis of A/-oxide (74) and evidenced by UV spectroscopy under the above conditions, decomposed at higher temperature to form the imino ether (76) by N—O bond cleavage and C -> O migration of an aryl group. 

Nature In an experiment in which one samples from a relatively small group of items, each of which is classified in one of two categories, A or B, the hypergeometric distribution can be defined. One example is the probabihty of drawing two red and two black cards from a deck of cards. The hypergeometric distribution is the analog of the binomial distribution when successive trials are not independent, i.e., when the total group of items is not infinite. This happens when the drawn items are not replaced. 

The existence of n-complex intermediates can be inferred from experiments in which they are trapped by nucleophiles under special circumstances. For example, treatment of the acid 1 with bromine gives the cyclohexadienyl lactone 2. This product results from capture of the n-complex by intramolecular nucleophilic attack by the carboxylate group ... 

Until the second half of the twentieth century, the structure of a substance—a newly discovered natural product, for example—was determined using information obtained from chemical reactions. This information included the identification of functional groups by chemical tests, along with the results of experiments in which the substance was broken down into smaller, more readily identifiable fragments. Typical of this approach is the demonstration of the presence of a double bond in an alkene by catalytic hydrogenation and subsequent determination of its location by ozonolysis. After-considering all the available chemical evidence, the chemist proposed a candidate structure (or structures) consistent with the observations. Proof of structure was provided either by converting the substance to some already known compound or by an independent synthesis. 

Protein tertiar-y structure is also influenced by the environment. In water a globular- protein usually adopts a shape that places its hydrophobic groups toward the interior, with its polar- groups on the surface, where they are solvated by water molecules. About 65% of the mass of most cells is water, and the proteins present in cells are said to be in their native state—the tertiary structure in which they express their biological activity. When the tertiar-y structure of a protein is disrupted by adding substances that cause the protein chain to unfold, the protein becomes denatured and loses most, if not all, of its activity. Evidence that supports the view that the tertiary structure is dictated by the primary structure includes experiments in which proteins are denatured and allowed to stand, whereupon they are observed to spontaneously readopt then native-state conformation with full recovery of biological activity. 

The earliest clue to the secret of fatty acid oxidation and breakdown came in the early 1900s, when Franz Knoop carried out experiments in which he fed dogs fatty acids in which the terminal methyl group had been replaced with a... 

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