Existing commercial chemical substances EINECS

The LD q for sodium bromide taken orally by rats is 3.5 g/kg body weight, and the TD q orally in rats is 720 mg/kg (8). RTECS Hsts data on reproductive effects in male and female rats. Sodium bromide is Hsted in the TSCA Inventory, the Canadian Domestic Substances Hst (DSL), the European Inventory of Existing Commercial Chemical Substances (EINECS), the Japanese Existing and New Chemical Substances (ENCS), and the Korean Existing Chemicals Hst (ECL). It is not regulated by the U.S. Department of Transportation. 

European Inventory of Existing Commercial Chemical Substances (EINECS), Luxembourg, The Netherlands, 1987. 

EC (2002) European inventory of existing commercial chemical substances (EINECS). http //esis.jrc.ec.europa.eu/index. php PGM = ein. Accessed 29 Oct 2011... 

The European Inventory of Existing Commercial Chemical Substances (EINECS) consists of substances on the market in the European Community between 1971 and 1981.19 These substances may be imported or manufactured without further notification. The list of 100,106 substances was published in 1990, and the contents are fixed. All chemicals that will be marketed after the September 18,1981 are not placed on the EINECS. These chemicals have to be notified before they will be placed on the market according to the sixth Amendment of Directive 67/548/EEC, Directive 79/831/EEC. Once assessed, these new chemicals are listed on the European List of New Chemical Substances (ELINCS).20 These substances must be notified by each new importer/manufacturer (although sometimes reduced notification packages may be accepted if the substance has already... 

CAS Registry Numbers are also widely used as standard identifiers for chemical substances in many of the commercial chemical inventories of governmental regulatory agencies, such as the Toxic Substances Control Act (TSCA) Inventory in the United States, the European Inventory of Existing Commercial Chemical Substances (EINECS), and the Canadian Domestic and Non-Domestic Substance Lists (DSL/NDSL). 

Not surprisingly, there are many synthetic chemicals and formulations commercially available. In Europe alone more than 100000 chemicals (not formulations) are on the European Inventory of Existing Commercial Chemical Substances (EINECS), which lists chemicals on the market before September 1981. This list differentiates between existing and all new chemicals produced since 1981 that have to be notified. During the period between 1981 and 2000 more than 2700 new substances were notified in Europe (Figure 1.3). For new substances, the obligatory notification system requires the manufacturer or importer to provide information suitable for risk assessment to be submitted to the competent authorities. The details required are dependent on the production volume or import quantities of the chemical. 

In 1982 the EC established the European Inventory of Existing Commercial Chemical Substances (EINECS). Only the chemicals listed in this register can be marketed without testing in the community. Those not listed ( New chemicals ) must be notified prior to commercialisation and this notification involves generation of hazard data, normally quite extensive. (See also chtqiter by Campbell.)... 

Chemicals controlled under separate EC legislation are exempt from notification, as are existing chemical substances, which are defined as those listed in the European Inventory of Existing Commercial Chemical Substances (EINECS). This is an inventory of substances supplied within the EC from 1 January 1971 to 18 September 1981, which were reported for inclusion by the sujpliers. EINECS is a closed inventory, and any substances omitted in error cannot now be included. 

The name and the registration number, CAS number [or - European Inventory of Existing Commercial Chemical Substances (EINECS) or - European List of Notified... 

Secondly, many of the world s trade lists and inventories of chemicals, both in printed form and as computer databases, primarily use nomenclature and do not contain structures. Examples include the European Customs Inventory of Chemicals and the European Inventory of Existing Commercial Chemical Substances (EINECS), both produced by the Commission of the European Communities. The lists of recommended International Non-proprietary Names (INN) for pharmaceutical substances, produced by the World Health Organisation, give the lUPAC name with the INN. Lists of hazardous substances also tend to use nomenclature, for instance the UN list of Recommendations on the Transport of Dangerous Goods. Users of these lists, such as the UK Laboratory of the Government Chemist, who need to pursue investigation of particular entries in other chemical information systems, are limited to nomenclature input. 

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