Estrogen and Progesterone

In addition lo the aforementioned corlicosleroidal hormones, the adrenal glands produce several oxysteroids and small amounts of testosterone and other androgens, estrogens, progesterone, and their metabolites. 

Suppression of postpartum lactation Estrogen, progesterone, and bromocriptine (a dopamine receptor agonist) are all effective in suppressing postpartum lactation. 

White MM, Zamudio S, Stevens T, et al, Estrogen, progesterone, and vascular ractivity potential cellular mechanisms, Endocr Rev 1995 16 739-751. 

Unlike the estrogen, progesterone and glucocorticoid receptors, it appears that the l,25(OH)2D3 steroid-receptor complex does not require a temperature-de-pendent transformation step, i.e., the binding of l,25(OH)2D3 does not appear to result in a dramatic change in the shape and size of the receptor. It has recently been demonstrated, however, that the binding of l,25(OH)2D3 to its receptor exhibits positive cooperativity the binding of one molecule of l,25(OH)2D3 to the re-... 

Steroid Receptors. Steroid receptors such as estrogen, progesterone, and androgen receptors are overexpressed in breast, ovarian, and prostate cancers. Estrogen and progesterone receptors are present in about 65% of human breast cancers. The presence or absence of these receptors in cases of breast carcinoma assists the determination of the therapeutic strategy (hormonal or chemical) that is likely to be effective. The successful Tc complex must cross the membrane lipid bilayer of the cell, and thus, the size and lipophilicity of the complex must be balanced with receptorbinding affinity. 

The hormonal events associated with ovulation are incompletely understood. Simplistically, a feedback loop is established between the hypothalamus-pituitary and the ovary at the onset of sexual maturity. Pituitary gonadotropins function to stimulate primitive follicles to secrete estrogen, progesterone, and... 

Ho, S.M. (2003) Estrogen, progesterone and epithelial ovarian cancer. Reproductive Biology and Endocrinology, 1, 73. 

Leitao MM, Soslow RA, Nonaka D, et al. Tissue microarray immunohistochemical expression of estrogen, progesterone, and androgen receptors in uterine leiomyomata and leiomyosarcoma. Cancer. 2004 101 1455-1462. 

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