Treated with Estrogen and Progesterone

it appears that hormone replacement can play a role in modifying certain risk factors associated with coronary heart disease in postmenopausal women, but the actual outcomes (heart attack, death) do not seem to be affected significantly by these hormonal interventions. Clearly, continued research in this area is needed to clarify if hormone replacement therapy can help decrease cardiac morbidity and mortality in certain postmenopausal women.60,121 

Hypogonadism. Estrogens, or a combination of estrogen and progesterone, may be used to treat abnormally low ovarian function. Appropriate use of these hormones induces the uterine changes and cyclic bleeding associated with the normal female reproductive cycle. 

Failure of Ovarian Development. Occasionally, the ovaries fail to undergo normal development because of hypopituitarism or other disorders. Estrogens may be given at the time of puberty to encourage development of secondary sexual characteristics (e.g., breast development). 

Menstrual Irregularities. Various problems with normal menstruation are treated by estrogen and progesterone. These hormones are used either separately or are combined to resolve amenorrhea, dysmenorrhea, and other types of functional uterine bleeding that are caused by a hormonal imbalance. 

Endometriosis. Endometriosis is a condition characterized by growths of uterinelike tissue that occur at various locations within the pelvic cavity. Progesterone and estrogen-progesterone combinations help suppress bleeding from these tissues and may help shrink the size of these growths. 

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