Drosophila regulation

Bone morphogenetic factors (DPP in Drosophila) Regulation of development Gastrulation Neurogenesis Chondrogenesis Development of eyes and wings and dorsalization in Drosophila... 

In Drosophila, Fat functions as a tumor suppressor gene and dachsous is involved in thorax, leg, and wing development. Several human and mouse homologs have been identified. FAT1 regulates actin filaments, and the Fail knockout leads to defects in glomerular slit formation [3]. 

Clos, J., Westwood, J.T., Becker, P.B., Wilson, S., Lambert, K., Wu, C. (1990). Molecular cloning and expression of a hexameric Drosophila heat shock factor subject to negative regulation. Cell 63, 1085-1097. 

Solomon, J.M., Rossi, J.M., Golic, K., McGarry, T., Lindquist, S. (1991). Changes in hsp70 alter thermotolerance and heat shock regulation in Drosophila. New Biologist 3, 1106-1120. 

Yost, H.J., Petersen, R.B., Lindquist, S. (1990). Post-transcriptional regulation of heat shock protein synthesis in Drosophila In Stress Proteins in Biology and Medicine (Morimoto, R., Tissieres, A. Georgopoulos, C., eds.), pp. 379-409, CSH Laboratory Press, Cold Spring Harbor. 

Edgar, B. A., and O Farrel], P. H. (1990). The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string. Cell 62 469-480. 

REGULATION OF THE DOPA DECARBOXYLASE GENE DURING DROSOPHILA DEVELOPMENT... 

Beall, C., and Hirsh, J. (1987). Regulation of the Drosophila dopa decarboxylase gene in neuronal and glial cells. Genes Dev. 1 510-520. 

Bray, S. J., and Hirsh, J. (1986). The Drosophila virilis dopa decarboxylase gene is developmentally regulated when integrated into Drosophila melanogaster. EMBO J. J 2305-2311. 

Dynlacht, B., Attardi, L., Admon, A., Freeman, M., and Tjian, R. (1989). Functional analysis of NTF-1, a developmentally regulated Drosophila transcription factor that binds neuronal cis-elements. Genes Dev. 3 1677-1688. 

Ellis, H. M., Spann, D. R., and Posakony, J. W. (1990). extramacrochaetae, a negative regulator of sensory organ development in Drosophila, defines a new class of helix-loop-helix proteins. Cell 61 27-38. 

Johnson, W. A., and Hirsh, J. (1990). A Drosophila POU, protein binds to a sequence element regulating gene expression in specific dopaminergic neurons. Nature 343 467-470. 

Lundell, M. J., and Hirsh, J. (1992). The zfh-2 gene product is a potential regulator of neuron-specific DOPA decarboxylase gene expression in Drosophila Dev. Biol. 154 84-94. 

Hafen, E., Levine, M and Gehring, W. J. (1984). Regulation of Antennapodia transcript distribution by the bithorax complex in Drosophila. Nature 307 287-289. 

Harding, K., Wedeen, C., McGinnis, W and Levine, M. (1985). Spatially regulated expression of homeotic genes in Drosophila. Science 229 1236-1242. 

White, R and Wilcox, M. (1985). Regulation of the distribution of ultrabithorax proteins in Drosophila. Nature 318 563-567. 

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