Drosophila melanogaster

FIGURE 12.28 Electron micrograph of Drosophila melanogaster chromatin after swelling reveals the presence of nncleosomes as beads on a string. (Electron micrograph courtesy of Oscar L. Miller, Jr, of the University of Virginia)... 

In the biosciences, a database is a curated repository of raw data containing annotations, further analysis, and links to other databases. Examples of databases are the SWISSPROT database for annotated protein sequences or the FlyBase database of genetic and molecular data for Drosophila melanogaster. 

Shaker-channels, eag (ether- -go-go)-channels, slo (slow-poke)-channels were cloned from behavioral Drosophila melanogaster mutants. The channels were named according to the Drosophila mutant phenotype, Shaker, ether-go-go, slow-poke. Subsequently, eag-cDNA was used to clone related voltage-gated potassium channel subunits erg (eag-related) and elk (eag-like). The human erg ortholog (HERG) mediates cardiac DCS. 

Studies in yeasts (Saccharomyces cerevisiae, Schizo-saccharomyces pombe), slime mould (,Dictyostelium discoideum), worm (Caenorhabditis elegans), fly (Drosophila melanogaster) and mammalian systems have all contributed to our understanding of TOR signalling. 

Steponkus, P.L., Caldwell, S. (1993). An optimized procedure for the cryopreservation of Drosophila melanogaster embryos. Cryo-Letters 14, 375-380. 

Gilmour, D.S. Lis, J.T. (1986). RNA polymerase II interacts with the promoter region of the noninduced hsp70 gene Drosophila melanogaster cells. Mol. Gen. Genet. 6, 3984-3989. 

Ritossa, F.M. (1963). New puffs induced by temperature shock DNP and salicylate in salivary chromosomes of Drosophila melanogaster. Drosophila Inf Service 37, 122-123. 

Xamena N, Velazquez A, Batiste-Alentom M, et al. 1988. Genotoxicity studies with four organophosphorus insecticides using the unstable white-zeste system of drosophila melanogaster. Mutat Res 204 251-256. 

Ardell, D.H. and Andersen, S.O., Tentative identibcation of a resilin gene in Drosophila melanogaster. Insect Biochem. Mol. Biol., 31, 965-970, 2001. 

Lehmann, F.O. and Dickinson, M.H., The production of elevated flight force compromises maneuverability in the fmit fly Drosophila melanogaster, J. Exp. Biol., 204, 627-635, 2001. 

Insect systems Drosophila melanogaster (sex-linked recessive lethal test) Recessive lethal mutation + Velazquez et al. 1984... 

U. K. Laemmli. Specific gain- and loss-of-function phenotypes induced by satellite-specific DNA-binding dmgs fed to Drosophila melanogaster. Mol. Cell 2000, 6, 1013-1024. 

Giot L, Bader JS, Brouwer C, Chaudhuri A, Kuang B, Li Y, et al. A protein interaction map of Drosophila melanogaster. Science 2003 302 1727-36. de Menezes MA, Barabasi AL. Fluctuations in network dynamics. Phys Rev Lett 2004 92 028701. 

Other eukaryotes included Apis mellifera, Bombyx mori, Caenorhabditis elegans, Drosophila melanogaster, Homo sapiens, Mus musculus, Tetraodon nigroviridis. 

At this time, more then thirty channel DNAs have been cloned and characterized from various sources, predominantly from Drosophila melanogaster, mouse, rat and human cDNA/genomic libraries [6-31]. Inspection of the derived primary K channel protein sequences indicates that voltage-gated channels belong to a... 

Silica gel plates also have been used for the separation of 16 different eye pigments of Drosophila melanogaster using two-dimensional development in nonpolar solvent systems [55]. Although not very common, two-dimensional development may be nsed in preparative scale on thick-layered plates for further analysis. 

Bray, S. J., and Hirsh, J. (1986). The Drosophila virilis dopa decarboxylase gene is developmentally regulated when integrated into Drosophila melanogaster. EMBO J. J 2305-2311. 

Budnik, V., and White, K. (1988). Catecholamine containing neurons in Drosophila melanogaster distribution and development. J. Comp. Neurol. 268 400-413. 

Hirsh, J., Morgan, B. A and Scholnick, S. (1986). Delimiting regulatory sequences of the Drosophila melanogaster Ddc gene. Mol. Cell. Biol. 6 4548-4557. 

Wright, T. (1987). The genetics of biogenic amine metabolism, sclerotization and melanization in Drosophila melanogaster. Genetics 24 127-222. 

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