Disease drug-induced

Generalized distal nephron dysfunction (type IV) Mineralocorticoid deficiency or resistance Tubulointerstitial disease Drug-induced hyperkalemia... 

Treatment of Parkinson s disease, drug-induced extrapyramidal reactions, except tardive dyskinesia... 

Indications Chronic obstructive pulmonary disease, drug-induced CNS depression Category Analeptic Half-life N/A... 

Mir iex), and ropinirole (Requip) are newer drugs used in the treatment of Parkinson s disease Drug-induced parkinsonism is treated with die anticholinergics benz-tropine (Cogentin) and trihexyiilienidyl (Artane). 

Identify the drugs used in management of tremor, Huntington s disease, drug-induced dyskinesias, and Wilson s disease. 

Doxapram is used to treat drug-induced respiratory depression and to temporarily treat respiratory depression in patients with chronic pulmonary disease This drug also may be used during the postanesthesia period when respiratory depression is caused by anesthesia It also is used to stimulate deep breathingin patients after anesthesia... 

Other Inflammatory Muscle Disorders Endocrine Myopathies Thyroid Disorders Adrenal Disorders Pituitary Disorders Parathyroid Disorders Pancreatic Disorders Drug-Induced and Toxic Myopathies Management of Muscle Disease... 

Corticosteroids a chronic painless myopathy associated with the long-term use of corticosteroids is a particularly common example of drug-induced muscle disorder. It is almost certain that mild cases are overlooked because steroids are so frequently used to treat inflammatory myopathies such as polymyositis. Fluorinated steroids are particularly frequently implicated, and the incidence of drug-induced muscle disease is dose and time-related. The presence of muscle weakness can even complicate topical steroid therapy. Corticosteroid-induced myopathy is mediated via intramuscular cytosolic steroid receptors. The steroid-receptor complexes inhibit protein synthesis and interfere with oxidative phosphorylation. The myopathy is associated with vacuolar changes in muscle, and the accumulation of cytoplasmic glycogen and mitochondrial aggregations. 

Henry, B and Brotchie, JM (1996) Potential of opioid antagonists in the treatment of levodopa, induced dyskinesias in Parkinson s disease. Drugs and Ageing 9 149-158. 

Evaluate the patient for the presence of drug-induced diseases, drug allergies, and drug interactions. 

Tisdale JE. Arrhythmias. In Tisdale JE, Miller DA, eds. Drug-Induced Diseases. Prevention, Detection and Management. Bethesda, MD American Society of Health-Systems Pharmacists 2005 289-327. 

Tubular and interstitial diseases (e.g., analgesic nephropathy, drug-induced nephritis, oxalate nephropathy, radiation nephritis, acute tubular necrosis, and sarcoidosis)... 

Evaluate other possible causes space-occupying lesion (which may or may not be malignant), drug-induced CNS disease, autoimmune disease, and trauma.8,9... 

Acute HIV Infection Diagnosis of acute HIV infection is difficult, since many patients are asymptomatic, or have nonspecific clinical symptoms similar to other common respiratory infections. If acute HIV infection is suspected, HIV antibody tests and a plasma HIV RNA concentration should be obtained. A clear diagnosis is made when an HIV antibody test is negative and the plasma HIV RNA concentration is high. There are limited outcomes data for treating acutely infected patients. Treatment of acute infection can decrease the severity of acute disease and decrease the viral set point this may decrease progression rates and reduce the rate of viral transmission.18-22 Limitations include an increased risk of chronic drug-induced toxicides and the development of viral resistance. 

Gleevec ) is a tyrosine kinase inhibitor used as first-line therapy in the majority of patients with CML. As a potent tyrosine kinase inhibitor, imatinib inhibits phosphorylation of various proteins involved in cell proliferation. Imatinib works by binding to the ATP-binding pocket of BCR-ABL.7 The drug induces complete hematologic responses in more than 95% of patients and complete cytogenetic responses in about 80% of patients in chronic phase.8 Most patients have traces of the disease when measured by RT-PCR and are not cured of their disease. 

Pharmacy application drug-induced gastric disease... 

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