Drug-induced lung disease

Collagen vascular disease Pneumoconiosis Drug-induced lung disease Pulmonary edema Infiltrative lung diseases Granulomatosis Tumor... 

Copper JA Jr. Drug-induced lung disease. Adv Intern Med 1997 42 231-268. 

Farer LS (1976) Isoniazid and liver injury. Ann Intern Med 84 753 Feinmann L (1975) Lung parenchymal changes due to ingested substances. Drug-induced lung disease pulmonary eosinophilia and sulphonamides. Proc R Soc Med 68 440 Fellner MJ (1970) Nebenwirkungen durch Isonicotinsaurehydrazid. Hautarzt 21 320 Flach A (1981) Photosensitivity to sulfisoxazole ointment. Arch Ophthalmol 99 609 Fleck R (1981) Nitrofurantoin toxicity. Pa Med 84 36... 

Hypersensitivity reactions are one of a number of different mechanisms producing drug-induced lung disease. These reactions result from interaction of drag with the immune system and... 

Drug-induced lung disease Penicillamine Methotrexate Gold... 

Ellis SJ, Cleverley JR, Muller NL (2000) Drug-induced lung disease high-resolution CT findings. AJR Am J Roentgenol 175 1019-1024... 

Anonymous (1974) Sulphasalazine-induced lung disease. Lancet 1 504 Aoki K, Shimotoge M, Saito T (1974) Studies on photosensitivity caused by sulfa drugs. J Dermatol (Tokyo) 1 99... 

Evans, P.H., Campbell, A.K., Yano, E. and Goodman, B. (1987). Phagocytic oxidant stress and antioxidant interactions in the pneumoconioses and dust-induced tumourigenic lung disease. In Free Radicals, Oxidant Stress and Drug Action (ed. C. Rice-Evans) pp. 213-235. Richelieu, London. 

There has been a previous report linking venlafaxine to pneumonia associated with eosinophilic infiltration, and SSRIs have been associated with drug-induced infiltrative lung disease. 

Of 54 patients with non-small-cell lung cancers treated with a combination of gemcitabine 1000 mg/m on days 1 and 8 and paclitaxel 200 mg/m on day 1, six had abnormal but significantly raised transaminases (55). The authors believed that this was drug-induced, but could not rule out underlying liver disease. 

---