Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Drug-induced autoimmune disease mechanisms

The mechanisms of autoimmunity may also entail interaction with MHC structures determined by the HLA alleles. Individuals carrying certain HLA alleles have been shown to be predisposed to certain autoimmune diseases, which may account in part for the genetic variability of autoimmunity. In addition, metabolites of a particular drug may vary between individuals to confound the development of drug-induced autoimmunity. Dendritic cells, such as the Langerhans cells of the skin and B lymphocytes that function to present antigens to Th cells, express class-II... [Pg.557]

Our currently poor understanding of the mechanisms leading to autoimmunity and autoimmune diseases following drug therapy is a major hurdle. To date, no animal model or assay can reliably predict the potential, of biopharmaceuticals or pharmaceuticals, for inducing autoimmunity reactions in human subjects. [Pg.491]

See other pages where Drug-induced autoimmune disease mechanisms is mentioned: [Pg.457]    [Pg.137]    [Pg.468]    [Pg.2]    [Pg.57]    [Pg.315]    [Pg.180]    [Pg.180]    [Pg.203]    [Pg.166]    [Pg.59]    [Pg.628]    [Pg.194]    [Pg.59]    [Pg.624]    [Pg.624]    [Pg.132]    [Pg.139]    [Pg.1399]    [Pg.112]    [Pg.7]    [Pg.60]    [Pg.409]    [Pg.184]    [Pg.242]    [Pg.246]    [Pg.73]    [Pg.505]    [Pg.119]    [Pg.197]    [Pg.426]    [Pg.221]    [Pg.234]    [Pg.466]    [Pg.171]    [Pg.31]    [Pg.901]    [Pg.58]    [Pg.256]   
See also in sourсe #XX -- [ Pg.460 , Pg.461 , Pg.462 ]



SEARCH



Autoimmune

Autoimmune diseases

Autoimmune diseases mechanisms

Autoimmunity, drug-induced

Autoimmunization

Disease drug-induced

Drug-disease

Drug-induced

Drugs mechanisms

© 2024 chempedia.info