Tubulointerstitial disease drug-induced

Generalized distal nephron dysfunction (type IV) Mineralocorticoid deficiency or resistance Tubulointerstitial disease Drug-induced hyperkalemia... [Pg.855]

Markowitz GS, Perazella MA. Drug induced renal failure a focus on tubulointerstitial disease. Clin Chim Acta 2005 351 31-47... [Pg.23]

Markowitz GS, Perazella MA Drug-induced renal failure a focus on tubulointerstitial disease. Clin Chim Acta 2005 351 31-47. Spanou Z, Keller M, Britschgi M, Yawalkar N, Fehr , Neuweiler , Gugger M, Mohaupt M, Pichler W Involvement of drug-specific cells in acute drug-induced interstitial nephritis. Am Soc Nephrol 2006 17 2919-27. [Pg.148]

The drugs that are most frequently responsible for tubulointerstitial nephritis are antibiotics, especially [T lactams, and non-steroidal anti-inflammatory drugs. Hypersensitivity reactions directed against the drug or its metabolites are usually found [43]. One study reported an association between tubulointerstitial nephritis and minimal change disease in 18 cases out of 27 patients with non-steroidal anti-inflammatory drugs-induced tubulointerstitial nephritis [51]. [Pg.56]

Non-steroidal anti-inflammatory drugs are known to induce a nephrotic syndrome in addition to acute tubulointerstitial nephritis (discussed in [77]). Glomerulopathies include minimal change disease, focal glomerulosclerosis that could represent a continuum with the former entity and membranous glomerulopathy. A review of 97 patients with non-steroidal anti-in-... [Pg.138]

Big Chemical Encyclopedia