Diphtheria-tetanus-acellular pertussis vaccine

Matheson AJ, Goa KL. Diphtheria-tetanus-acellular pertussis vaccine adsorbed (Triacelluvax DTaP3-CB) a review of its use in the prevention of Bordetella pertussis infection. Paediatr Drugs 2000 2(2) 139-59. 

Rowe. 1, Macaubas C, Monger I. Holt BJ, Harvey J, Poolman JT, Loh R, Sly PD, Holt PG Heterogeneity in diphtheria-tetanus-acellular pertussis vaccine-specific cellular immunity during infancy Relationship to variations in the kinetics of postnatal maturation of systemic Thl function. J Infect Dis 2001 184 80-88. 

ACIP Advisory Committee on Immunization Practices CDC Centers for Disease Control and Prevention CMV-IVIG cytomegalovirus intravenous immunoglobulin DTaP diphtheria-tetanus-acellular pertussis vaccine HBIg hepatitis B immune globulin HDCV human diploid cell vaccine (rabies)... 

Pertussis Vaccine (Including Diphtheria-Tetanus-Acellular Pertussis Vaccine) [SED 15, 2780 SEDA-31, 520 SEDA-32, 580 SEDA-33, 657]... 

Diphtheria, tetanus, acellular pertussis Dtap 0.5 mL Intramuscular Systemic neurologic reaction from previous vaccine Brachial neuritis Cried for 3 hours non-stop after previous dose Temperature greater than 40.5°C (105°F)... 

Following hematopoietic stem cell transplantation the patient will need virtually all routine vaccines to be administered again however, the patient will not be able to mount an adequate response for 6 to 12 months post-transplant. Diphtheria, tetanus, acellular pertussis, Haemophilus influenzae type b, hepatitis B, pneumococcal, and inactivated poliovirus should be given at 12,14, and 24 months post-hematopoietic stem cell transplantation. Inactivated influenza vaccine should be given yearly, starting 6 months after transplant. Measles, mumps and rubella can be given 2 years after transplant and varicella vaccine is contraindicated.16... 

For the combination vaccine use the diphtheria-tetanus-acellular pertussis (DTPa), inactivated polio (IPV) and Haemophilus influenzae type b (Hib) (Infanrix-Polio+H i ) vaccine (GlaxoSmithKline, Rixensart, Belgium). 

The pharmacogenomics analysis of samples from a clinical study with an aluminum hydroxide-adsorbed vaccine (diphtheria-tetanus-acellular pertussis/polio/ Haemophilus influenzae) in infants is described. These instructions can easily be adapted to clinical studies of other vaccines with changes to the type of administered vaccine, administration route, vaccination ages, and so on. This method is therefore also suitable for assessing vaccine responses in adults and to study the cellular reactions in clinical subjects who have experienced adverse reactions. 

Certain vaccines manufactured hy various companies are considered interchangeable. Hepatitis A and hepatitis B vaccines are considered interchangeable. It is preferable to use diphtheria-tetanus-acellular pertussis (DTaP) vaccine from the same manufacturer to complete the entire primary series. However, immunization should not be delayed if the particular type of vaccine administered for the initial doses cannot be ascertained easily. Finally, all licensed Hemophilus influenzae type b conjugate vaccines are considered interchangeable for the primary series of three doses of vaccine. ... 

Sun Y, Christensen J, Hviid A, Li J, Vedsted P, Olsen J, et al. Risk of febrile seizures and epilepsy after vaccination with diphtheria, tetanus, acellular pertussis, inactivated poliovirus, and haemophilus influenzae type b. JAMA 2012 307(8) 823-31. 

Zimmermann U, Gavazzi G, Richard P, Eymin C, Soubeyrand B, Baudin M. Immunogenicity and safety of a booster dose of diphtheria, tetanus, acellular pertussis and inactivated poliomyelitis vaccine (Tdap-IPV Repevax ) administered concomitantly versus non-concomitantly with an influenza vaccine (Vaxigrip ) to adults aged Oyears an open-label, randomised trial. Vaccine 2013 31(ll) 1496-502. 

Diphtheria and tetanus toxoids and acellular pertussis vaccine (DTaP). The... 

In the 1940s, diphtheria toxoid was combined with tetanus toxoid and whole cell pertussis vaccines, and later with the acellular pertussis vaccine. The diphtheria toxoid, tetanus toxoid, and acellular pertussis vaccine are part of the routine childhood immunization schedule. Diphtheria toxoid is also combined with tetanus toxoid and is commonly used as a booster vaccine. The pediatric product (DT) has a higher amount of diphtheria toxoid than does the adult product (Td). Diphtheria toxoid is not available as an individual vaccine. 

The first pertussis whole cell vaccine was a mixture of killed organisms that was associated with frequent local and systemic reactions. In the late 1980s, an acellular pertussis vaccine was introduced that contains purified pertussis components that are immunogenic but associated with fewer adverse reactions. Acellular pertussis vaccine is available in combination with tetanus and diphtheria toxoids. Pertussis is not available as a separate vaccine component. In the spring of 2005, the Food and Drug Administration (FDA) approved tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccines for use in adolescents and adults. 

Tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) is recommended as a single booster for the following groups in place of a tetanus booster. 

Tetanus, diphtheria, and acellular pertussis (Td/Tdap) vaccination. 

Acellular pertussis vaccine is usually administered in combination with diphtheria and tetanus toxoids (as DTaP). 

Acel-Imune Diphtheria, tetanus toxoids acellular pertussis vaccine Jan. 6, 1992 Takeda Chemical Industries /American Cyanamid... 

Nakayama, T., Aizawa, C., and Kuno-Sakai, H. 1999. A clinical analysis of gelatine allergy and determination of its causal relationship to the previous administration of gelatin-containing acellular pertussis vaccine combined with diphtheria and tetanus toxoids. J Allergy Clin Immunol 103(2) 321—325. 

Advisory Committee on Immunization Practices (ACIP). Use of diphtheria toxoid-tetanus toxoid-acellular pertussis vaccine as a five-dose series. MMWR Recomm Rep 2000 49(RR-13) l-8. 

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