Dimethyl isobutyl amine

Attempts have also been made to solvent-extract thorium directly from the sulphate liquor obtained by the acid breakdown of monazite. Tributyl phosphate can be used as the solvent provided a large concentration of nitric acid is added to the liquor before extraction. In order to make the process economic, a high proportion of the nitric acid must then be recovered by distillation of the raffinate liquor. Processes are also being developed which are based upon the use of higher alkyl phosphate or amine solvents to extract from sulphate solutions without the addition of nitric acid, as in the case of uranium. For example bis(l-isobutyl 1-3-5 dimethyl-hexyl) amine, di-2-ethylhexyl hydrogen phosphate and Primene JM-T have been used. 

UDMH is known to be miscible with the following wafer, benzene, triethyl benzene, toluene, kerosene, ethyl alcohol, isobutyl alcohol, n-butyl ether, n-amyl ether, n-hexyl ether, diethyl ether, petroleum ether, petroleum naphtha, n-heptane, n-hexane, n-octane, n-decane, n-dodecane, n-hexadecane, cyclohexane, 1,2-dimethyl cyclohexane, phenyl cyclohexane, n-tetradecane, trichloroethylene, dichloroethylene, perchloroethylene, 1,1,1-trichloroethane, triethyl amine, ethylenediamine, diethylene triamine, acetonitrile, aniline, cumene, tetra-hydronaphthalene, tetraethylene pentamine, ethylene glycol and hydrazine (Ref 4)... 

The use of NBD-Cl for the fluorescence analysis of alkylamine-generating pesticides has been investigated [173]. A two-phase reaction system is employed for the hydrolysis and labeling of N-methyl- and N,N-dimethyl-carbamate pesticides. The residue is hydrolyzed in 0.1 M sodium carbonate and the liberated amine is treated with NBD-Cl in an organic phase (IBMK, isobutyl methyl ketone) above the aqueous layer. An aliquot portion of the organic layer is used for chromatography. The reactions involved are shown in Fig. 4.65. 

Dimethyl-, Diethyl-, Diisopropyl-, Di-butyl-, Dicyclohexyl-, Dibenzylamine, Poly-S-isobutyl-ethylenimine Amines, tert.. Trialkyl-amines... 

Diethylamine Miscible Dieth ether Miscible bis-(2.ethylhexyl)amine 0.7 Diethyl sulfide MlKible Di-isobutyl carbinol Miscible Di-isobutylene 3.3 <0.6% DMSO soluble in di-isobutylei>e) Disopropyl ether 11 Dimethyl ether 4.4 Dimethyl formamide Miscible Morpholine Naphthalene Neoprene Nitrobenzene Oleic acid Ouricuri wax Oxalic add Palmitic acid Paraffin Paraformaldehyde Miscible 40 Insol. Miscible Misdble 38 100 Insoluble Insoluble Miscible Inso 1 Slightly soluble... 

The synthetic route to iV-aryl [3.2.2] cryptands 5a and 5b is shown in the Scheme. Starting from the A-aryl diethanolamine, reaction with two equivalents of chloro-acetic and /-BuOK in t-BuOH followed by conversion of the diacid to the diester for purification gave la and lb in yields of 49 and 25%, respectively. Subsequent acid-catalyzed hydrolysis produced the dicarboxylic acid amine hydrochlorides 2a and 2b quantitatively. Attempts to form the diacid chloride of 2a resulted in an unreactive deep blue-colored substance of unknown identity. Ring closure was effected by adaptation of a method from peptide synthesis [8]. Mixed anhydrides 3a and 3b formed by reaction with two equivalents of isobutyl chloroformate in the presence of triethylamine were cyclized with l,10-diaza-18-crown-6 in toluene to produce the corresponding cryptand diamides 4a and 4b in 36 and 32% yields, respectively. Reduction with borane-dimethyl sulfide in THF provided 74% yields of 5a and 5b. 

These novel metabolites may be derived from four amino acids tryptophan, anthranilic acid, valine, and alanine (or methylalanine). Deoxynor-tryptoquivalone (43) may be the first metabolite formed in the pathway of the tryptoquivaline biosynthesis. By oxidation of the secondary amine to the hydroxylamine, nortryptoquivalone (= tryptoquivalone) (32) would be formed from 43. If the isobutyl side chain is lost by further oxidation, tryptoquivaline J (39) and E (34) would be derived from these tryptoqui-valones, respectively. On the other hand, if reduction occurred on the carbonyl in the side chain, deoxynortryptoquivaline (42) and nortrypto-quivaline (FTD) (40) would be derived, respectively, from these tryptoqui-valones. The geminal dimethyl group at position 15 appeared to be formed by the participation of methylalanine in the biosynthesis, and the actual incorporation of " C-labeled methylalanine into tryptoquivaline (FTC) and tryptoquivaline I has been demonstrated (M. Yamazaki, unpublished work). 

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