0,0-Diethyl 0- -4-pyrimidinyl phosphorothioate

Diazinon (diethyl-2-isopropyl-6-methyl-4-pyrimidinyl phosphorothioate or 0,0-diethyl-o-(2-isopropyl-6-methyl-4-pyrimidyl phosphorothioate)... 

Snyder et al. [253] compared supercritical fluid chromatography with classical sonication procedures and Soxhlet extraction for the determination of selected insecticides in soils and sediments. In this procedure the sample was extracted with carbon dioxide modified with 3% methanol at 350atm and 50°C. An excess of 85% recovery of organochlorine and organophosphorus insecticides was achieved. These included Dichlorvos, Diazinon, (diethyl-2-isopropyl-6-methyl 4-pyrimidinyl phosphorothioate), Ronnel (i.e. Fenchlorphos-0,0 dimethyl-0-2,4,5-trichlorophenyl phosphorothioate), Parathion ethyl, Methiadathion, Tetrachlorovinphos (trans-2-chloro-l-(2,4,5 trichlorophenyl) vinylchlorophenyl-O-methyl phenyl phosphoroamidothioate), Endrin, Endrin aldehyde, pp DDT, Mirex and decachlorobiphenyl. 

Plant Diaziuou was rapidly absorbed by and translocated in rice plants. Metabolites identified in both rice plants and a paddy soil were 2-isopropyl-4-methyl-6-hydroxypyrimidine (hydrolysis product), 2-(l -hydroxy-l -methyl)ethyl-4-methyl-6-hydroxypyrimidine, and other polar compounds (Laanio et al, 1972). Oxidizes in plants to diazoxon (Laanio et al., 1972 Ralls et al, 1966 Wolfe et al., 1976) although 2-isopropyl-4-methylpyrimidin-6-ol was identified in bean plants (Kansouh and Hopkins, 1968) and as a hydrolysis product in soil (Somasundaram et al., 1991) and water (Suffet et al., 1967). Five d after spraying, pyrimidine ring-labeled C-diazinon was oxidized to oxodiazinon which then hydrolyzed to 2-isopropyl-4-methylpyrimidin-6-ol which, in turn, was further metabolized to carbon dioxide (Ralls et al, 1966). Diazinon was transformed in field-sprayed kale plants to hydroxydiazinon 0,0-diethyl-0-[2-(2 -hydroxy-2 -propyl)-4-methyl-6-pyrimidinyl] phosphorothioate which was not previously reported (Pardue et al., 1970). 

Di-(2-Ethylhexyl)Acid Phosphate Di-(2 Ethylhexyl)Adipate Di-(2-Ethylhexyl)Phosphate Di-(2-Ediylhexyl)Phosphoric Acid Di(2-Ethylhexyl) Phthalate Di-(2-Ethylhexyl)Sulfosuccinate Sodium Salt 0,0-Diethyl 0-(2-Isopropyl-6-Methyl -4-Pyrimidinyl)Phosphorothioate 0,0-Diethyl-0-(2-Isopropyl-6-Methyl-4-Pyrimidinyl) Phosphorothioate... 

Diethyl-0-(2-isopropyl-4-methyl-6-pyrimidinyl) phosphorothionate 0,0-diethyl-0-[6-methyl-2-(1 -methylethyl)-4-pyrimidinyl] phosphorothioate others... 

Diazinon is the Ciba-Geigy Corporation trademark name for the active ingredient 0,0-diethyl-0-(2-[l-methylethyl]-4-methyl-6-pyrimidinyl) phosphorothioate. This insecticide is produced commercially by reacting 2-isopropyl-4-hydroxy-6-methylpyrimidine and 0,0-diethyl phosphorochloridothioate (HSDB... 

Harris LW, JH Fleisher, Innerebner, et al. 1969. The effects of atropine-oxime therapy on cholinesterase activity and the survival of animals poisoned with diethyl-0-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate. Toxicol Appl Pharmacol 15 216-226. 

Chemical Name 0,0-diethyl 0-2-isopropyl-6-methylpyrimidin-4-yl phosphorothioate 0,0-diethyl-0-(2-isopropyl-6-methyl 4-pyrimidinyl) phosphorothioate 0,0-diethyl 2-isopropyl-4-methylpyrimidinyl-6-thiophosphate Uses nonsystemic insecticide to control flies, aphids and spider mites in soil, fruit, vegetables and ornamentals also... 

A novel device was designed to estimate the dislodgeability of dust-associated pesticide residues by skin contact (Edwards and Lioy, 1999). Called the EL Sampler , the device consists of a spring-loaded assembly that permits the sampling medium to be pressed lightly (12g/cm or 1160 Pa) onto the surface to be monitored. A 10-cm x 15-cm Empore C-18 extraction membrane was used for the sampling medium. The material was chosen after controlled experiments on particle adhesion showed it to pick up the same distribution of test dust particle sizes as the human hand. In studies in which the EL sampler was pressed onto polyethylene surfaces coated with house dust and then sprayed with a solution of pesticides in 2-propanol, the device was found to collect 35%, 31 %, 32% and 18 %, respectively, of chlorpyrifos, diazinon (0,0-diethyl 0-[6-methyl-2-(l-methylethyl)-4-pyrimidinyl] phosphorothioate), malathion and atrazine (6-chloro-A -ethyl-A -isopropyl-l,3,5-triazine-2,4-diamine). Parallel studies with human hand presses (full hand at 6.8 kg = ca. 6900 Pa) yielded collection efficiencies of 42 %, 29 %, 43 % and 21 %, respectively. 

DIETHYL-0-6-METHYL-2-IS0PR0PYL-4-PYRIMIDINYL PHOSPHOROTHIOATE see DCM750 DIETHYLMETHYL METHANE see MNI500 1,1-DIETHYL-3-METHYL-3-NITROSOUREA see DJP600... 

Diethyl-0-2-isopropyl-4-methyl-6-pyrimidinyl-phosphorothioate Spectracide ... 

Gysin, H. and A. Margot. Chemistry and Toxicological Properties of 0,C>-Diethyl-C>-(2-isopropyl-4-methyl-6-pyrimidinyl) Phosphorothioate (Diazinon), J. Agric. Food Chem., 6(12) 900-903 (1958). 

Photolytic. Direct photolysis of diazinon should occur since it absotbs UV light at wavelengths greater then 290 mn (Gore et al., 1971). 0,(9-Diethyl-C>-[2-(2 -propyl)-4-methyl-6-pyrimidinyl]phosphorothioate (hydroxydiazinon) was reported as a product of UV irradiation of diazinon (Paris and Lewis, 1973). When diazinon in an aqueous buffer solution (25°C and pH 7.0) was exposed to filtered UV light Qi >290 nm) for 24 hours, 36% decomposed to 2-isopropyl-6-methylpyrimidin-4-ol. The photolysis half-life for this reaction was calculated to be 15 days (Bmkhard and Guth, 1979). 

Diazinon (phosphorothioic acid 0,0-diethyl 0-(6-mcthyl-2-(l-mcthylcthyl)-4-pyrimidinyl) ester) is an organophosphorus compound with an anticholinesterase mode of action. It is used extensively to control hies, lice, insect pests of ornamental plants and food crops, as well as nematodes and soil insects in lawns and croplands. Diazinon degrades rapidly in the environment, with half-time persistence usually less than 14 days. But under conditions of low temperature, low moisture, high alkalinity, and lack of suitable microbial degraders, diazinon may remain biologically active in soils for 6 months or longer. 

DIETHYL/ MIN0)-6-METHYL-4-PYRIMIDINYL)-0,0-DIMETHYL PHOSPHOROTHIOATE see DIN800 7-DIETHYLAMINO-5-METHYL-s-TRIAZOLO(l,5-a)PYRIMIDINE see DI0200... 

Phosphorothioic acid 0- 2-(dimethylamino)-6-methyl-4-pyrimidinyl] 0,0-diethyl ester. 

Diethylamino)-6-methyl-4-pyrimidinyl)-0,0-dimethyl phosphorothioate 2-Diethylamino-6-methylpyrimidin-4-yl dimethyl phosphorothionate. See Pirimiphos-methyl 3-(Diethylamino) phenol m-Diethylaminophenol N,N-Diethyl-3-aminophenol. See N,N-Diethyl-m-aminophenol N,N-Diethyl-m-aminophenol CAS 91-68-9 EINECS/ELINCS 202-090-9 Synonyms 3-(Diethylamino) phenol m-Diethylaminophenol N,N-Diethyl-3-aminophenol... 

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