Desorption electrospray ionization mass

Z. Takats, I. Cotte-Rodrfguez, N. Talaty, H. Chen, and R. G. Cooks. Direct, Trace Level Detection of Explosives on Ambient Surfaces by Desorption Electrospray Ionization Mass Spectrometry. Chem. Commun., no. 15 (2005) 1950-1952. 

Kauppila, T. J., Wiseman, J. M., Ketola, R. A., Kotiaho, T., Cooks, R. G., and Kostiainen, R. (2006). Desorption electrospray ionization mass spectrometry for the analysis of pharmaceuticals and metabolites. Rapid Commun. Mass Spectrom. 20 387-392. 

Kertesz, V., and Van Berkel, G. J. (2008). Improved imaging resolution in desorption electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom. 22 2639-2644. 

Chen, H., Li, M., Zhang, Y.-P., Yang, X., Lian, J.-J. and Chen, J.-M. (2008) Rapid analysis of SVOC in aerosols by desorption electrospray ionization mass spectrometry. Journal of the American Society for Mass Spectrometry, 19, 450-4. 

Ellis S, Wu C, Deeley J, ZhuX, Truscott R, Panhuis J, Cooks R, Mitchell T, Blanksby S (2010) Imaging of human lens lipids by desorption electrospray ionization mass spectrometry. J Am Soc Mass Spectrom 21 2095-2104. doi 10.1016/j.jasms.2010.09.003... 

Manicke N, Dill A, Ifa D, Cooks R (2010) High-resolution tissue imaging on an orbitrap mass spectrometry by desorption electrospray ionization mass spectrometry. J Mass Spectrom 45 223-226. doi 10.1002/jms,1707... 

Wiseman J, Ifa D, Zhu Y, Kissinger C, Manicke N, Kissinger P, Cooks R (2008) Desorption electrospray ionization mass spectrometry imaging drug and metabolites in tissues. Proc Natl Acad Sci USA 105(47) 18120-18125. doi 10.1073/pnas.0801066105... 

Analyses of tropane alkaloids are mainly carried out by GC and HPLC and to a lesser extent by CE. This review describes recent applications developed for the analysis of this class of compounds in plant materials and biological matrices. Of course, mass spectrometry is generally used as the detection technique because of its high sensitivity and selectivity, but other techniques such as UV, fluorescence, flame ionization detection, nuclear magnetic resonance, among others have also been investigated. Finally, desorption electrospray ionization mass spectrometry is reported as a new interesting detection technique for the rapid analysis of samples without any sample preparation. 

Venter, A., Sojka, P.E., and Cooks, R.G., Droplet dynamics and ionization mechanisms in desorption electrospray ionization mass spectrometry, Anal. Chem., 78(24), 8549, 2006. 

Chen, H. et al., Desorption electrospray ionization mass spectrometry for high-throughput analysis of pharmaceutical samples in the ambient environment, Anal. Chem., 77(21), 6915, 2005. 

Takats, Z. et al., Direct, trace level detection of explosives on ambient surfaces by desorption electrospray ionization mass spectrometry, Chem. Commun., 15, 1950, 2005. 

Kauppila, T.J. et al., New surfaces for desorption electrospray ionization mass spectrometry Porous silicon and ultra-thin layer chromatography plates, Rapid Commun. Mass Spectrom., 20, 2143, 2006. 

Kauppila, TJ. et al., Rapid analysis f metabolites and drugs of abuse from urine samples by desorption electrospray ionization-mass spectrometry, Analyst, 132, 868, 2007. 

D Agostino, P.A. Chenier, C.L., Desorption electrospray ionization mass spectrometric analysis of organo-phosphorus chemical warfare agents using ion mobihty and tandem mass spectrometry. Rapid Contmun. Mass Spectrom. 2010, 24,1613-1624. 

Thunig J, Flo L, Pedersen-Bjergaard S, Hansen SH, Janfelt C. Liquid-phase microextraction and desorption electrospray ionization mass spectrometry for identification and quantification of basic drugs in human urine. Rapid Commun Mass Spectrom 2012 26 133-140. 

Wiseman, J.M. Ifa, D.R. Venter, A. Cooks, R.G. Ambient molecular imaging by desorption electrospray ionization mass spectrometry. Nat. Protocols 2008,3, 517-524. 

Figure 4.6 Online coupling of an electrochemical flow cell with nanospray desorption electrospray ionization MS. (a) Scheme showing the configuration of the EC/nanospray desorption electrospray ionization MS with an electrochemical flow cell. Nanospray desorption electrospray ionization MS spectra acquired when the dopamine solution flowed through the thin-layer electrochemical cell with an applied potential of (b) 0.0 and (c) 1.5 V. (d) EIC of m/z 152 acquired when the dopamine solution flowed through the thin-layer electrochemical cell [ 175]. Reprinted with permission from Liu, R, Lanekoff, I.T., Laskin, ]., Dewald, H.D., Chen, H. (2012) Study of Electrochemical Reactions Using Nanospray Desorption Electrospray Ionization Mass Spectrometry. Anal. Chem. 84 5737-5743. Copyright (2012) American Chemical Society...

Miao, Z Chen, H. (2009) Direct Analysis of Liquid Samples by Desorption Electrospray Ionization-Mass Spectrometry (DESI-MS). J. Am. Soc. Mass Spectrom. 20 10-19. 

Girod, M Moyano, E., Campbell, D.L, Cooks, R.G. (2011) Accelerated Bimolecu-lar Reactions in Microdroplets Studied by Desorption Electrospray Ionization Mass Spectrometry. Chem. Sci. 2 501-510. 

Li, J., Dewald, H.D., Chen, H. (2009) Online Coupling of Electrochemical Reactions with Liquid Sample Desorption Electrospray Ionization-Mass Spectrometry. Anal. Chem. 81 9716-9722. 

Brown, T.A., Chen, H Zare, R.N. (2015) Identification of Fleeting Electrochemical Reaction Intermediates Using Desorption Electrospray Ionization Mass Spectrometry. J. Am. Chem. Soc. 137 7274-7277. 

Zhang, T., Zhou, W., Jin, W., Jin, Q., Chen, H. (2013) Direct Detection of Aromatic Amines and Observation of Intermediates of Schiff-base Reactions by Reactive Desorption Electrospray Ionization Mass Spectrometry. Microchem. J. 108 18-23. 

Xu, G., Chen, B., Guo, B., He, D., Yao, S. (2011) Detection of Intermediates for the Eschweiler-Clarke Reaction by Liquid-phase Reactive Desorption Electrospray Ionization Mass Spectrometry. Analyst 136 2385-2390. 

Paglia, G Ifa, D.R., Wu, C Corso, G., Cooks, R.G. (2010) Desorption Electrospray Ionization Mass Spectrometry Analysis of Lipids after Two-dimensional High-Performance Thin-Layer Chromatography Partial Separation. Anal. Chem. 82 ... 

Nyadong, L., Hohenstein, E.G., Galhena, A., Lane, A.L., Kubanek, J., Sherrill, C.D., Eernandez, F.M. (2009) Reactive Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) of Natural Products of a Marine Alga. Anal. Bioanal. Chem. 394 245-254. 

Sparrapan, R., Eberlin, L.S., Haddad, R., Cooks, R.G., Eberlin, MJ4., August , R. (2006) Ambient Eberlin Reactions via Desorption Electrospray Ionization Mass Spectrometry. J. Mass Spectrom. 41 1242-1246. 

Nyadong, L., Late, S., Green,M.D., Banga,A., Fernandez, F.M. (2008) Direct quantitation of active ingredients in solid artesunate antimalarials by noncovalent complex forming reactive desorption electrospray ionization mass spectrometry. J. Am. Soc. Mass Spectrom., 19, 380-388. 

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