Design and Structure

Knittings consist of interlocked meshes that are produced perpendicular to the production direction. A loop that is connected to other loops is called a mesh. Meshes possess a head, a foot, and two legs. They are connected via two upper and two lower crossing points, as shown in Fig. 5.3. The meshes perpendicular to the production direction are called course those meshed in the production direction are called wales.  

According to the position of the bottom crossing points, one distinguishes between purl and plain stitches. A plain stitch has its feet under and its legs over the head of the previous stitch (Fig. 5.3(a)). A purl stitch has its feet over and its legs under the head of the previous stitch, see Fig. 5.3(b). 

According to the arrangement of right and left stitch sides in knitwear, these can be distinguished by their binding group back and face, double jersey, and left-left knitwear. Back-and-face knitwear has only plain stitches on one side and purl stitches on the other. Double-jersey knitwear shows plain stitches on each stitch side. Plain and purl stitch sides alternate in the direction of one stitch row (basic double jersey). Left-left knitwear shows purl stitches on each side. Plain and purl stitches alternate in the direction of a stitch wale (basic left-left). See Table 5.1 for information on mesh structure and formation. 

Structure different on each side Face only plain meshes, 

Back only purl meshes ( wave structure ) 

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Battery systems of complex design and structure using—at least for one electrode—expensive materials are (for economic reasons) mainly conceived as storage batteries. Primary (and "reserve") versions of the zinc/silver oxide battery [(-) Zn/KOH/AgO (+)] — as a first example—are only used in particular cases where the question of cost is not crucial, e.g., for marine [26-28] and space applications [29]. 

Elices, M. Structural Biological Materials Design and Structure-Property Relationships, Elsevier, New York, 2000. 

There are three main contributions that structural methods are making to the drug discovery process—structural biology, structure-based design, and structure-based discovery. 

To understand the role of silk protein design and -structure assembly, it is important to consider the exact sequence of events in the aggregation... 

The Design and Structure-Functional Properties of DNA-Based Immunomodulatory Sequences... 

Singh, S. 2000. Chemistry, design, and structure - Activity relationship of cocaine antagonists. Chemistry Revue, 100 925-1024. 

Although there is a wide variety of cooling tower manufacturers, designs, and structural materials used, particular types of tower are often associated with specific industries. This may further concentrate the focus of survey questioning to center around potential problem areas specific to the industry in question. For example ... 

Resch et al. [39] summarise and discuss the whole chain from data retrieval, processing, analysis and visualisation. The general design and structure of such a chain is depicted in Fig. 2, starting with generalised sensors. These sensors can be traditional fixed monitors, but can also be mobile sensors installed on cars, ships or at short-term locations, for example on lampposts. These mobile or moveable sensors can be equipped with a geo-positioning system (GPS) to be employed in geo-information systems (GIS) (e.g. [40]). These applications have been made possible by miniaturisation of the GPS as well as the transfer of data by mobile phone systems. 

VII. Library Design and Structure-Based Drug Design.361... 

VII. LIBRARY DESIGN AND STRUCTURE-BASED DRUG DESIGN... 

DeGrado WF, Summa CM, Pavone V, Nastri F, Lombardi A (1999) De novo design and structural characterization of proteins and metalloproteins, Annu Rev Biochem, 68 779—819... 

The microenvironment in which crystals form is important for understanding the control over mineral formation in biology. In each of the three systems described above, the microenvironments are very different in terms of shape and scale, confining components and the manner in which the space is further sub-divided. Clearly however a key element of the microenvironment is the nucleation site itself. There are numerous indirect observations in vivo and in vitro demonstrating that much of the control over mineral formation is exercised through the design and structure of the nucleation site. We know very little, however, about actual nucleation sites in vivo. In fact to date no protein or other specific components of a nucleation site have been unequivocally identified, let alone characterized. This is certainly one of the major immediate goals of this field. 

Nakamura, M., Mori, Y., Okuyama, K., Tanikawa, K., Yasuda, S., Hanada, K., and Kobayashi, S., 2003, Chemistry and biology of khafrefungin. Large-scale synthesis, design, and structure-activity relationship of khafrefungin, an antifungal agent. Org. Biomol. Chem. 1 3362-3376. 

Baru, M. B., Cherskii, V. V., Danilov, A. V., Moshnikov, S. A., and Mustaeva, L. G. (1995) Automatic SynChrom system for solid phase peptide synthesis and liquid column chromatography. I. Principles of design and structural constituents. Russ. J. Bioorch. Chem. 21, 498-505. 

Artificial intelligence for intellectual problem solving synthesis design and structure elucidation. 

Abe S, Ueno T, Reddy PAN, Okazaki S, Hikage T, Suzuki A, Yamane T, Nakajima H, Watanabe Y. Design and structure analysis of artificial metalloproteins selective coordination of His64 to copper complexes with square-planar structure in the apo-myoglobin scaffold. Inorg. Chem. 2007 46 5137-5139. Ohashi M, Koshiyama T, Ueno T, Yanase M, Fuji H, Watanabe Y. Preparation of artificial metalloenzymes by insertion of chromium Schiff base complexes into apomyoglobin mutants. Angew. Chem Int. Ed. 2003 42 1005-1008. 

Hurley JH, Baase WA, Matthews BW. Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme. J. Mol. Biol. 1992 224 1143-1159. 44. 

The QSPR/QSAR methods have many direct benefits like property prediction, target molecular design, and structural refinement, and indirectly it can help to... 

The Inverse Protein Folding Problem Protein Design and Structure Prediction in the Genomic Era... 

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