Ligand- and Structure-based Drug Design

Depending on the information available about the protein structure and the ligands binding to a particular target, four different cases can be distinguished in drug design, as listed in Table 10.4-2. 

Protein structure know 11 dt novo design, receptor-based 3D searching stnjcture-based design, docking 

Thus there is a distinction between ligand- and structure-based drug design, which are described in more detail in Sections 10.4.6.1 and 10.4.6.2. 

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