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Replication deoxyribonucleic acid

Latt, S.A. (1973). Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes. Proc. Nat. Acad. Sci. U.S.A. 770 3395-3399. [Pg.231]

Sauerbier, W., Brautigam, a. R. Control of gene function in bacteriophage T4. II. Synthesis of messenger ribonucleic acid and protein after interrupting deoxyribonucleic acid replication and glucosylation. J. Virol. 5, 179-187 (1970). [Pg.129]

Latt, S. A. Microfluorometric analysis of deoxyribonucleic acid replication kinetics and sister chromatid exchanges in human chromosomes. J. Histochem. Cytochem. 1974,22,478-491. [Pg.235]

Adams, R. L. P., Abrams, R., and Lieberman, L, 1966, Deoxycytidylate synthesis and entry into the period of deoxyribonucleic acid replication in rabbit kidney cells, J. Biol. Chem. 241 903. [Pg.285]

Marks, D. B., Paik, W. K., and Borun, T. W., 1973, The relationship of histone phosphorylation to deoxyribonucleic acid replication and mitosis during the HeLa S-3 cell cycle, /. Biol Chem. 248 5660. [Pg.290]

Tobia, A. M., Schildkraut, C. L., and Maio, J. J., 1970, Deoxyribonucleic acid replication in synchronized cultured mammalian cells. I. Time of synthesis of molecules of different average guanine + cytosine content, J. Mol. Biol. 54 499. [Pg.293]

True to their word Watson and Crick followed up their April 25 paper with another on May 30 This second paper Genetical Implications of the Struc ture of Deoxyribonucleic Acid outlines a mechanism for DNA replication that is still accepted as essentially correct... [Pg.1167]

DNA (deoxyribonucleic acid) (Section 28 7) A polynucleotide of 2 deoxynbose present in the nuclei of cells that serves to store and replicate genetic information Genes are DNA... [Pg.1281]

Deoxyribonucleic acid (DNA, Fig. 3-13) is the genetic material of all organisms, including plants, animals, and microorganisms. (Some viruses lack DNA, but use RNA (ribonucleic acid) in its place.) DNA carries all the hereditary information of the organism and is therefore replicated and passed from parent to offspring. RNA is formed on DNA in the nucleus of the... [Pg.61]

Deoxyribonucleic acid (DNA) topoisomerases (topos) are ubiquitous enzymes that can manipulate DNA by changing the number of topological links between two strands of the same or different DNA molecules [1]. These enzymes are involved in many cellular processes, such as replication, recom-... [Pg.44]

The nucleus contains bundles of a fibrous material known as chromatin, which is made up of mixed proteins and deoxyribonucleic acid (DNA), the substance that carries the genetic information of the living organism of which the cell is a component. All cells replicate by division. When a cell replicates, DNA in the chromatin of the nucleus passes the genetic information from one generation to the next one. As the cell divides, the chromatin clusters into rodlike structures known as chromo-... [Pg.288]

The discovery of the base-paired, double-helical structure of deoxyribonucleic acid (DNA) provides the theoretic framework for determining how the information coded into DNA sequences is replicated and how these sequences direct the synthesis of ribonucleic acid (RNA) and proteins. Already clinical medicine has taken advantage of many of these discoveries, and the future promises much more. For example, the biochemistry of the nucleic acids is central to an understanding of virus-induced diseases, the immune re-sponse, the mechanism of action of drugs and antibiotics, and the spectrum of inherited diseases. [Pg.215]

Another dinuclear Mn enzyme with quite a different functionality is MnRNR. Cell replication and deoxyribonucleic acid (DNA) formation require the reduction of the 2 hydroxyl group of a ribonucleoside phosphate [13a]. [Pg.394]

Replicators are a specialized type of assembler capable of making copies of themselves. They are similar in concept to one of the best-known of all biochemical molecules, deoxyribonucleic acid (DNA). [Pg.75]

In addition to the 1988 Nobel Prize (which she shared with Hitchings and British scientist Sir James Black), Elion received other awards and several honorary doctorates. Active in public service, she served on both national and international health committees. She died on February 20, 1999, in Chapel Hill, North Carolina, see also Deoxyribonucleic Acid (DNA) DNA Replication Nucleic Acids Nucleotide. [Pg.41]

As much of the terminology used in molecular biology may be unfamiliar to some readers, it is appropriate to define some of the vocabulary and this is given in an appendix to this chapter. There are two types of nucleic acids, the ribonucleic acids (RNA) and the deoxyribonucleic acids (DNA). Genetic information is carried in the linear sequence of nucleotides in DNA. Each molecule of DNA contains two complementary strands of deoxyribonucleotides which contain the purine bases, adenine and guanine and the pyrimidines, cytosine and thymine. RNA is single-stranded, being composed of a linear sequence of ribonucleotides the bases are the same as in DNA with the exception that thymine is replaced by the closely related base uracil. DNA replication occurs by the polymerisation of a new complementary strand on to each of the old strands. [Pg.140]

The two major classes of nucleic acids are ribonucleic acids (RNA) and deoxyribonucleic acids (DNA). In a typical cell, DNA is found primarily in the nucleus, where it carries the permanent genetic code. The molecules of DNA are huge, with molecular weights up to 50 billion. When the cell divides, DNA replicates to form two copies for the daughter cells. DNA is relatively stable, providing a medium for transmission of genetic information from one generation to the next. [Pg.1140]


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