Coupling continuous process

In the Aquafluor process [G4] developed by the General Electric Company, most of the plutonium and fission products in irradiated light-water reactor (LWR) fuel are separated from uranium by aqueous solvent extraction and anion exchange. Final uranium separation and purification is by conversion of impure uranyl nitrate to UFg, followed by removal of small amounts of PuF , NpFg, and other volatile fluorides by adsorption on beds of NaF and Mgp2 and a final fractional distillation. A plant to process 1 MT/day of irradiated low-enriched uranium fuel was built at Morris, Illinois, but was never used for irradiated fuel because of inability to maintain on-stream, continuous operation even in runs on unirradiated fuel. The difficulties at the Morris plant are considered more the fault of design details than inherent in the process. They are attributed to the attempt to carry out aqueous primary decontamination, denitration, fluorination, and distillation of intensely radioactive materials in a close-coupled, continuous process, without adequate surge capacity between the different steps and without sufficient spare, readily maintainable equipment [G5, R8]. 

Pulsed amperometric detection (PAD), introduced by Johnson and LaCourse (64, 65) has greatly enhanced the scope of liquid chromatography/electrochemistry (66). This detection mode overcomes the problem of loss of activity of noble metal electrodes associated with the fixed-potential detection of compounds such as carbohydrates, alcohols, amino acids, or aldehydes. Pulsed amperometric detection couples tlie process of anodic detection with anodic cleaning and cathodic reactivation of a noble metal electrode, thus assuring a continuously cleaned and active... 

NMR spectroscopy, 93. See also Proton NMR integrations Hoechst continuous process, 548 Homo-coupling reactions, aryl halide, 486-487 Homopolymers, 7 Hot-cast prepolymer method, 211 Hot phosgenation, 222 Houvink-Sakurada equation, 286 HTMAB. See Hexadecyltrimethylammonium bromide (HTMAB)... 

In ToF-MS, the ion source is pulsed to create packets of ions. In the conventional procedure, the system waits for all the ions in a packet to reach the detector before injecting the next packet of ions. Complications arise when ToF-MS is coupled to a continuous ion source. Such coupling is therefore often accomplished by the orthogonal extraction approach, in which a segment of the ion stream is accelerated orthogonally by a push-out pulse. However, in this process, up to 95 % of the information contained in the ion steam is lost. Recently, Hadamard transform time-of-flight mass spectrometry (HT-ToFMS) was developed to couple continuous ion... 

One of the obvious areas where flow chemistry comes into its own is in the arena of catalysed reactions and continuous processing. An excellent example of this is the Suzuki reaction (for recent reviews on the Suzuki Cross-Coupling reaction, see Miura 2004 Beilina et al. 2004 ... 

The dominant role of the batch operation over the continuous process throughout the pigment industry is somewhat in contrast to the patent literature, which includes numerous proposals for complete azo pigment manufacture by the continuous process as well as descriptions of the partial steps, such as the diazotization or the coupling reaction. 

Coupling a membrane process to this technology it is possible to obtain the separation of the clarified solution or the reaction product and also the recovery and the reuse of the catalyst. In fact, the choice of an appropriate membrane allows a selective separation of the product to be performed and to maintain the catalyst in the reaction environment in a continuous process that increases the efficiency of the whole system. 

Although the use of membrane reactors for the retention of the enzyme is mostly applied in continuous processes, some authors used a membrane batch reactor in order to reuse the enzyme in consecutive cycles [11, 74]. Flock et al. used a membrane unit coupled to the reactor with recycling of both permeate and retentate streams to the reactor vessel. A valve at the outlet of the membrane maintained pressure within the range fixed by the manufacturer [74]. Pasta et al. operated a reactor with the membrane inside, emptied the reactor content at scheduled times, and thereafter, replenished it with fresh solution of the substrate and the oxidizing system [11]. 

If the voltammetric scan is not reversed after the first oxidation, a second oxidation (Epa = 0.2-0.3 V) is observed (Figure 6c). This oxidation renders the lower potential oxidation irreversible (Epa = 0-0.1 V) and also leads to the observation of an irreversible reduction at negative potentials (Epc = —0.8 to —0.9 V). It has not been possible to measure accurately the number of electrons involved in either the second oxidation or in the coupled reduction process by coulometry due to the formation of films on the electrode surfaces. However, in comparison with that observed for the first oxidation, the peak currents are consistent with one- and two-electron processes, respectively. In spite of the irreversible nature of the cyclic voltammogram, continuous cycling be-... 

In membrane reactors, the reaction and separation processes take place simultaneously. This coupling of processes can result in the conversion enhancement of the thermodynamically-limited reactions because one or more of the product species is/are continuously removed. The performance of such reactors depends strongly on the membrane selectivity as well as on the general operahng conditions which influence the membrane permeability. 

The use of isolated enzymes, therefore, has great advantages. However, for the preparative applications of isolated redox enzymes, especially for continuous processes, effective and simple methods for the continuous recycling of the active cofactors have to be available. In addition, such systems have to be stable over long times and the separation of the product must be simple to render technical processes economically feasible. Until now, this problem has been generally solved by coupling of the synthetic enzyme with a... 

The Leeds Northrup Co. has developed a two-couple continuous curve recorder for automatically heating furnaces to definite temperatures. As applied in carburizing and tempering of steel one thermocouple is placed in the furnace chamber and the other in contact with the steel piece. The controller automatically maintains the furnace for instance at 1,000°C. until the steel has reached 900°C. and then it drops the furnace to 900 C. Such an arrangement for control can be applied to a great many processes. 

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