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Coronary arteriosclerosis

Simeoni E, Winkelmann BR, Hoffmann MM, et al. Association of RANTES G-403A gene polymorphism with increased risk of coronary arteriosclerosis. Eur Heart J 2004 25(16) 1438-1446. [Pg.228]

Brensike JF, Levy RI, Kelsey SF, Passamani ER, Richardson JM, Loh IK, et al. Effects of therapy with cholestyramine on progression of coronary arteriosclerosis results of the NHLBI Type II Coronary Intervention Study. Circulation 1984 69 313-24. [Pg.969]

Therapy in coronary insufficiency (angina pectoris, coronary infarct, coronary occlusion, and coronary arteriosclerosis) is aimed at increasing the blood supplied to the muscle of the heart. No alkaloids have exhibited significant promise in this disease the nitrite compounds, heparin, and the khellin glycosides, are in current use. [Pg.81]

In the western countries the most prevalent form of heart disease is coronary heart disease, i.e. the sequelae of atherosclerosis [18] of the coronary arteries. Culmination of coronary arteriosclerosis is manifested by erratic heart activity, arrhythmia or fibrillation, i.e. in drastic cases by coronary occlusion, myocardial infarction and sudden death. Mortality from coronary heart disease varies greatly from one country to the other. The following statistics represent the death rate due to coronary heart disease among the male population between the ages of... [Pg.220]

Waters DD, Alderman EL, Hsia J, Howard BV, Cobb FR, Rogers WJ, et al. Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary arteriosclerosis in postmenopausal women a randomized controlled trial. J Am Med Assoc 2002 288(19) 2432- 0. [Pg.235]

Mammals lack the ability to synthesize astaxanthin or convert dietary astaxanthin into vitamin A. Unlike p-carotene, astaxanthin has no pro-vitamin activity in these animals. Astaxanthin has been shown in both in vitro and in a study with human subjects to be effective for the prevention of the oxidation of low-density protein, suggesting that it can be used to prevent arteriosclerosis, coronary artery disease, and ischemic brain development. A number of astaxanthin health products are under study. [Pg.407]

Adams MR, Kaplan JR, Manuck SB, Koritnik DR, Parks JS, Wolfe MS, Clarkson TB (1990) Inhibition of coronary artery atherosclerosis by 17-beta estradiol in ovariec-tomized monkeys. Lack of an effect of added progesterone. Arteriosclerosis 10 1051— 1057... [Pg.237]

PI. Paillard, F., Guillo, P., Ruelland, A., Morin, A., Lebreton, H., Mabo, P., and Daubert, C., Lp(a) is an independent predictor of the severity of coronary atherosclerosis. Arteriosclerosis (Dallas) 10, 790a-791a (1990). [Pg.127]

Pregnancy (ergotamine s powerful uterine stimulant actions may cause fetal harm) hypersensitivity to ergot alkaloids peripheral vascular disease (eg, thromboangiitis obliterans, leutic arteritis, severe arteriosclerosis, thrombophlebitis, Raynaud s disease) hepatic or renal impairment severe pruritus coronary artery disease hypertension sepsis. The use of potent CYP3A4 inhibitors (ritonavir, nelfinavir, indinavir, erythromycin, clarithromycin, troleandomycin, ketoconazole, itraconazole) with dihydroergotamine is contraindicated. [Pg.969]

Contraindications Coronary artery disease, hypertension, impaired liver or renal function, malnutrition, peripheral vascular diseases, such as thromboangiitis obliterans, syphilitic arteritis, severe arteriosclerosis, thrombophlebitis, Raynaud s disease, sepsis, severe pruritus... [Pg.371]

Contraindications Renal impairment coronary or cerebral arteriosclerosis concurrent use with phosphodiesterase-5 (PDE-5) inhibitors including sildenafil (>25 mg), tadalafil, or vardenafil hypersensitivity to phentolamine or related compounds. [Pg.977]

The effects of chronic hypertension on the human organism are, with one exception, of little interest to the investigator studying pathogenesis, although of great import to the sufferer and his physician. That exception is failure of the kidneys. Disease and failure of the heart are probably caused by chronic overstrain, often associated with another metabolic disease, arteriosclerosis of the coronary arteries. They account for about two thirds of the deaths primarily due to hypertension. Strokes of apoplexy, or cerebral vascular accidents, from rupture or thrombosis of a cerebral artery weakened by disease cause another sixth, uremia about one twelfth, and other conditions the remainder (28). Except for uremia, these events are usually the result of overwork and increased arterial tension. Only rarely does the heart escape hypertrophy. [Pg.3]

The determination of cholesterol is important for the diagnosis and prevention of a number of clinical disorders such as hypertension, arteriosclerosis, cerebral thrombosis and coronary heart disease. As the majority of cholesterol in human blood is present in an esterified form, a separate saponification step is required to obtain a total cholesterol analysis early methods for this involved caustic and toxic reagents, long analysis times and a relatively large sample volume. Free cholesterol can be determined chromatographically, although this requires cumbersome and expensive laboratory-based equipment. Modern methods use the enzyme cholesterol esterase to release esterified cholesterol which is then oxidised by a second enzyme, cholesterol oxidase (ChOx, Fig. 23.3) [48]. [Pg.504]

Hawthorn is stated to possess cardiotonic, coronary vasodilator, and hypotensive properties. Traditionally, it is used for cardiac failure, myocardial weakness, paroxysmal tachycardia, hypertension, arteriosclerosis, and Buerger s disease. [Pg.96]

Schaefer, E. J., Heaton, W. H., Wetzel, M. G., and Brewer, H. B., Jr., Plasma apolipoprotein A-I absence associated with a marked reduction of high density lipoproteins and premature coronary artery disease. Arteriosclerosis 2, 16-26 (1982). [Pg.291]

Morpholin-4-yl-piperizyl) quinazoline derivatives, (I), prepared by Kanter (2) were effective as kinase phosphorylation inhibitors and used in the treatment of proliferative diseases such as arteriosclerosis, vascular reobstruction after percutaneous coronary angioplasty, and bypass operation cell-proliferative. Quinazoline derivatives, (n), prepared by Lambert (3) were effective against the Src family of nonreceptor tyrosine kinases inhibitors and used in the treatment of uncontrolled cellular proliferation. [Pg.289]

Gurfinkel E, Bozovich G, Daroca A et al. (1997). Randomized trial of roxithromycin in non-Q-wave coronary syndromes ROXIS Pilot Study. Lancet 350 404-407 Haapanen A, Koskenvuo M, Kaprio J et al. (1989). Carotid arteriosclerosis in identical twins discordant for cigarette smoking. Circulation 80 10-16... [Pg.25]

In hypovolemic patients, in patients with impaired sympathetic autonomic activity, and in patients operated on in the anti-Trendelenburg position, extreme falls in blood pressure can occur with D-tubocurarine. Hypotension is aggravated by the use of halothane in particular, and by other drugs that produce circulatory depression. In such cases, and in patients with hypertension, coronary artery disease, and arteriosclerosis, D-tubocurarine is better avoided. [Pg.3534]

Atherosclerosis is a major cause of death in most industrial societies. The characteristic lesion of this disease, the atherosclerotic plaque, is found in the intima of large- and medium-sized arteries. An additional problem with advanced plaques is that thrombus formation is likely to occur in regions of plaque rupture. The combination of the two events can lead to partial or even total occlusion of major arteries. If this occurs in one or more of the coronary arteries, a serious or even fatal MI may result. A discussion of arteriosclerosis and exogenous agents that can modulate this condition is presented below. [Pg.481]

For several years, lovastatin represented the commerically most successful drug from nature. Named mevinolin, it was discovered as a metabolite from Aspergillus terreus cultures at the US company Merck by a target-directed screening for inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, a key enzyme of cholesterol biosynthesis [32]. Cholesterol, which in humans more than one-half of the total body cholesterol is derived from its de novo biosynthesis in the liver, is the major component of atherosclerotic plaques built up as fatty deposits on the inner walls of arteries, thus contributing to arteriosclerosis and coronary heart diseases [33]. [Pg.111]

Ischaemic heart disease arises if one or more of the coronary arteries become partially occluded (by atheroma or arteriosclerosis). This leads to reduction in blood flow to the myocardium. [Pg.57]


See other pages where Coronary arteriosclerosis is mentioned: [Pg.590]    [Pg.580]    [Pg.108]    [Pg.159]    [Pg.73]    [Pg.17]    [Pg.590]    [Pg.580]    [Pg.108]    [Pg.159]    [Pg.73]    [Pg.17]    [Pg.255]    [Pg.5]    [Pg.114]    [Pg.128]    [Pg.112]    [Pg.721]    [Pg.220]    [Pg.206]    [Pg.220]    [Pg.255]    [Pg.272]    [Pg.100]    [Pg.492]    [Pg.255]    [Pg.423]    [Pg.1000]    [Pg.622]    [Pg.795]    [Pg.192]    [Pg.693]    [Pg.76]    [Pg.50]   
See also in sourсe #XX -- [ Pg.220 ]




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Arteriosclerosis

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