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Combinational therapy

Synergistic effects are accomplished by the use of these combinations. Resistance to this combined therapy, either by bacteria or proto2oa, emerges very slowly (18). [Pg.466]

Bendamustine is a useful antineoplastic drug for the treatment of non-Hodgkin s lymphomas, multiple myeloma and as a partner drug in the combination therapy of some solid tumors. The cross-resistance with other alkylating drugs is not complete. Myelosuppression and lymphocytopenia is its main dose-limiting toxicity. [Pg.57]

Antiprotozoal Drugs. Figure 5 Artemisinin combination therapy (ACT) Adding a 3-days artesunate course to mefloquine cleats the parasitaemia much more rapidly (A — A). The remaining parasites are exposed to higher mefloquine levels in ACT (B) compared to mefloquine monotherapy (B (with permission White, 1997 Antimicrob Agents Chemother 41 1413-1422). [Pg.177]

COMT inhibitors rescue l-dopa and improve the brain entry of L-dopa by decreasing 3-OMD formation in peripheral tissues. The dose of L-dopa could be decreased, compared with the present combination therapy. Dose interval of L-dopa could also be prolonged. Further, COMT inhibitors should decrease fluctuations of dopamine formation in the brain. [Pg.337]

The benzodiazepine, lorazepam, acts allosterically on GABAa receptors to facilitate the actions of GABA. Lorazepam has some antiemetic activity in cancer chemotherapy. When used in combination therapy, it does not appear to add to antiemetic control but may contribute to a reduction in anxiety. [Pg.462]

During the maintenance phase dose reductions are aimed. However, in most cases a dual or triple combination therapy is still necessary. The use of drugs with different mechanisms of immunosuppressive action allows the application of lower doses additionally resulting in decreased toxicity. [Pg.621]

Similar to HBV, infections with hepatitis C virus (HCV) have a high rate of progression from an acute to a chronic state that frequently leads to cirrhosis or hepatocellular carcinoma [2]. Monotherapy for HCV infection with IFN-a or combined therapy with ribavirin and IFN-a is associated with initial rates of response as high as 40%. The rates of sustained responses are, however, lower and also depend on the viral genotype. In patients infected with HCV genotype 2 or 3, the response was maximal after 24 weeks of treatment, whereas patients infected with genotype 1 -the most frequent in the USA and Europe - required a minimum treatment course of 48 weeks for an optimal outcome. [Pg.645]

So far, five different protease inhibitors have been approved by the FDA for the treatment of HIV infection [3, 4]. Clinical trials in which protease inhibitors were evaluated in monotherapy demonstrated the potency of this class of inhibitors (decrease in HIV RNA levels, increase in CD4 cell counts). Treatment regimens were subsequently broadened to include reverse transcriptase inhibitors in combination with protease inhibitors. The result of these clinical trials has led to a list of guidelines with recommendations for the optimal treatment options. Prolonged control of the infection with combination therapy (highly active antiretroviral therapy, HAART ) could be shown. [Pg.1286]

In those with gout, the serum uric acid level is usually elevated. Sulfinpyrazone increases the excretion of uric acid by the kidneys, which lowers serum uric acid levels and consequently retards the deposit of urate crystals in the joints. Probenecid (Benemid) works in the same manner and may be given alone or with colchicine as combination therapy when there are frequent, recurrent attacks of gout. Probenecid also has been used to prolong the plasma levels of the penicillins and cephalosporins. [Pg.187]

Type 2 diabetes combination therapy with a sulfonylurea to enhance glycemic control... [Pg.500]

Continue Combination Therapy HbA C q 6 months Add intermediate bedtime insulin or add third oral agent or switch to insulin... [Pg.502]

Hodgkin s disease, lymphocytic lymphoma, histiocytic lymphoma, mycosis fungoides, testicular cancer, Kaposi s sarcoma, breast cancer Acute leukemia, combination therapy for various cancers... [Pg.586]

Combination therapy Nausea, vomiting, diarrhea, in patients with Dukes stomatitis, anorexia stage C colon cancer... [Pg.590]


See other pages where Combinational therapy is mentioned: [Pg.497]    [Pg.63]    [Pg.314]    [Pg.212]    [Pg.78]    [Pg.422]    [Pg.524]    [Pg.257]    [Pg.55]    [Pg.125]    [Pg.133]    [Pg.143]    [Pg.143]    [Pg.144]    [Pg.157]    [Pg.176]    [Pg.200]    [Pg.200]    [Pg.200]    [Pg.334]    [Pg.361]    [Pg.1011]    [Pg.1012]    [Pg.1022]    [Pg.1124]    [Pg.1250]    [Pg.122]    [Pg.477]    [Pg.502]    [Pg.502]    [Pg.47]    [Pg.51]    [Pg.27]    [Pg.29]    [Pg.323]    [Pg.326]    [Pg.8]   
See also in sourсe #XX -- [ Pg.116 ]




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Acarbose insulin therapy combination

Angina combination therapy

Angina pectoris combination therapy

Anti-HIV Drug Combinations Use of Highly Active Antiretroviral Therapy

Antibiotic resistance combined drug therapy

Antibiotic-steroid combination therapy

Anticancer drugs combination therapy with

Anticoagulant drugs combination therapy

Antidepressants combination therapy with

Antifungal agents combination therapy with

Antihypertensives combination therapy

Antimicrobial combination therapy with

Antipsychotics combination therapy

Anxiety disorders combination therapy

Artemisinin combination therapies

Artemisinin-based combination therapies

Artemisinin-based combination therapies ACTS)

Asthma combination therapy

Benign prostatic hyperplasia combination therapy

Breast cancer combination therapy

Cancer combination therapy

Cholesterol combination therapy

Chronic obstructive pulmonary disease combination therapy

Clavulanic acid combination therapy

Clozapine combination therapy

Cognitive-behavioral therapy combined with

Combination therapies antimicrobials

Combination therapies chemotherapy

Combination therapies, for

Combination therapy

Combination therapy

Combination therapy Combinatorial

Combination therapy antibiotics

Combination therapy approach

Combination therapy chemistry

Combination therapy definition

Combination therapy focusing

Combination therapy refinement

Combination therapy respiratory system

Combination therapy scaffolds

Combination therapy with DNA-damaging agents

Combination therapy with antiviral agents

Combined chemotherapy photodynamic therapy

Combined chemotherapy photothermal therapy

Combined gene/cell therapy

Combined modality therapy

Combined therapies avoiding

Combined therapies case studies

Combined therapies combination peels

Combined therapies complications

Combined therapies long-term follow

Combined therapies patient education

Combined therapies patient evaluation

Combined therapies procedures

Combined therapy

Combined therapy

Congestive heart failure combination therapy

Corticosteroids combination therapy with NSAID

Depression combination therapy

Diabetes mellitus type insulin therapy combination

Estrogen/progestogen therapy continuous-combined

Fibrinolytic therapy combination

Fibrinolytic therapy combining

Fixed combination therapy

Free combination therapy

Gastroesophageal reflux disease combination therapy

Gene therapy severe combined immunodeficiency

Gentamicin combination therapy

Hormonal therapy estrogen/progestogen combinations

Human immunodeficiency virus combination therapy, AIDS

Hyperlipidemias combination therapy

Hyperpigmentation combined therapies

Hypertension combination therapy

INDEX combination drug therapy

In combination therapy

Infections combination therapy

Insulin therapy combination

Insulin therapy metformin combination

Insulin therapy sulphonylureas combination

Metastases combined therapies

Obidoxime combination therapy

Outcome evaluation combination therapy

Pain management combination therapy

Pneumonia combination therapy

Practice guidelines, combination therapy

Pralidoxime combination therapy

Prescription drugs combination therapies

Protease inhibitors in combination therapy

Pseudomonas infections combination therapy

Psychoeducation combination therapy

Rebetron Combination Therapy

Rheumatoid arthritis combination therapy

Severe combined immunodeficiency syndrome gene therapy

Statins combination therapy

Sulfonamides combination therapy

Tetracyclines combination therapy

Thrombolysis combined pharmacologic therapy

Tissue regeneration combination therapy

Urinary tract infections combination therapy

Versus Combination Therapy

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