Pralidoxime combination therapy

If exposure is through ingestion, the victim should seek medical help immediately. Emesis should not be induced. Initial management involves establishment of adequate ventilation and maintenance of adequate respiratory function. Activated charcoal therapy may be used to retard absorption from the gastrointestinal tract. Atropine sulfate alone, or in combination with pralidoxime chloride, can be administered as an antidote. Atropine is initially administered intravenously at a dosage of 1-2 mg kg every 5-10 min until... 

It has not been published how Novichok Nerve Agents will respond to treatment with standard antidotes (i.e., atropine in combination with pralidoxime chloride. See Class Indices COl through C03). It is known that some of the agents in this class have been designed to be resistant to therapy. 

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