Cockroach allergens

Campbell EM, Charo IF, Kunkel SL, et al. Monocyte chemoattractant protein-1 mediates cockroach allergen-induced bronchial hyperreactivity in normal but not CCR2 / mice the role of mast cells. J Immunol 1999 163(4) 2160-2167. 

Santos, A. B., Chapman, M. D., Aalberse, R. C., Vailes, L. D., Ferian, V. P., Oliver, C., Rizzo, M. C., Naspitz, C. K., and Arruda, L. K. (1999). Cockroach allergens and asthma in Brazil Identification of tropomyosin as a major allergen with potential cross-reactivity with mite and shrimp allergens. /. Allergy Clin. Immunol. 104, 329-337. 

Lehrer, S.B., Reese, G. 1998. Cross-reactivity between cockroach allergens and arthropod, nematode and mammalian allergens. Revue Francaise D Allergologie Et D Immunologie Clinique 38(10) 846-850. 

Among household insect pests, cockroaches are associated with the incidence of bronchial asthma, particularly, in children. Cockroach s body parts, cast skin, egg shells, and fecal material contain several major and minor allergens involved in triggering an asthma attack (Helm et al., 1996 Yu and Huang, 2000). A majority of urban residents with asthma are sensitive to cockroach allergens. The fact that the number of cockroaches seen in the... 

Rosenstreich DL, Eggleston P, Kattan M, et al The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner-city children with asthma. N Engl J Med 1997 336 1356-1363. 

Sarpong SB, Wood RA, Karrison T, Eggleston PA Cockroach allergen (Bla g 1) in school dust. J Allergy Clin Immunol 1997 99 486-492. 

Papouchado BG, Chapoval SP, Marietta EV,Weiler CR, David CS. Cockroach allergen-induced eosinophilic airway inflammation in HLA-DQ/human CD4(+) transgenic mice. J Immunol 2001 167 4627-4634. 

Pollart S.M., Smith T.F., Morris E.C., Gelber L.E.. Platts-Mills T.A.E. and Chapman M.D. (1991) Environmental exposure to cockroach allergens analysis with monoclonal antibody-based enzyme immunoassays. J. Allergy Clin. Immunol., 87, 505-510. 

Campbell EM, Kunkel SL, Stneter RM, Lukacs NW Temporal role of chemokines in a murine model of cockroach allergen-induced aunvay hyperreactivity and eosino-pbilia J Immunol 1998, 161 7047-7053... 

In addition, Raukas-Kivioja et al. (2007) reported a study of 1,346 Estonia adults aged 17-69 years, who lived in urban or suburban areas before the age of 5, and had a significantly increased risk for allergic sensitization compared to those who were rural residents. In this study, the most common sensitizer in urban areas was cockroach allergens whereas, in rural areas, the primary sensitizer was storage mites. Positive skin prick test (SPT) results were found in 27% vs. 40% of the study subjects who had lived in a rural vs. urban environment during early childhood the highest prevalence was found in the most heavily polluted urban areas (Raukas-Kivioja et al. 2007). 

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