Classification and labeling

The general principles of the classification and the subsequent possible hazard labeling of chemical products are laid down in Article 4 of the 7 th Amendment (Directive 92/32/EEC) to Directive 67/548/EEC for substances and Article 3 [5] of the Dangerous Preparations Directive (Directive 88/379/EEC) for preparations (mijctures of substances). 

Physical-chemical hazards explosive, oxidizing, extremely flammable,  

The criteria for these hazard categories are given in Annex VI, which also includes a labehng guide to the assignment of symbols and the R-(risk) and S-(safety) phrases (hsted in Annexes 11-IV) to be used on the product label. 

There is a requirement to assess aU products by comparing the available data with the criteria given in the legislation, whether or not this leads to a subsequent hazard classification and associated hazard labeling. 

An important feature of these labehng requirements in the European Union is that they aim not only to provide appropriate hazard warning and safety advice on the label in the interests of worker protection but also, through the appHcation of rigid criteria, to achieve a harmonized approach within the single market. In order to achieve these dual objectives, it is perhaps inevitable that the EU requirements are more prescriptive than their United States counterparts under TSCA and the OSH A Hazard Communication Standard. 

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Substances or preparations requiring to be labelled with the risk phrase R45 (may cause cancer) or R49 (may cause cancer by inhalation) under CHIPS are listed in Table 5.16 after the 5th edition of the Approved Supply List (Information approved for the classification and labelling of substances and preparations dangerous for supply). This list excludes certain coal and oil-based substances which attract the phrase R45 only when they contain a certain percentage of a marker substance (e.g. benzene). 

HS(Rjl7 A guide to the Classification and Labelling of Explosives Regulations 1983... 

Approved guide to the classification and labelling of substances and preparations dangerous for supply Safe working m confined spaces - Approved Code of Practice, Regulations and guidance - Confined Spaces Regulations 1997... 

Impose requirements with respect to the safety and security of explosives carried by road. Explosives include explosive articles or explosive substances which have been assigned on classification to Class 1 (or are classified) in accordance with the Classification and Labelling of Explosives Regulations 1983. 

Explosive chemicals tend to be governed by separate legislation, e.g., in the UK, The Classification and Labelling of Explosives Regulations 1983. These require the HSE to classify any explosive before it may be supplied. Under the scheme, explosives are labelled according to a classification based on hazard division (Table 12.7), and on compatibility (Table 12.8), which takes into account their sensitivity, explosivity and chemical nature. Labels are diamond shaped the top half is reserved for the pictograph and division number, the bottom half shows the hazard code and the classification number. Figure 12.1 shows the label for Class 1, Division 1.1, 1.2 or 1.3 explosive. 

Unlike the requirements for >1 tonne, member states have differing test requirements and formats for Limited Announcement (which must be made in each member state in which the substance is supplied). The requirements for the UK are given in Table 12.9. The test requirements for Base Set (Level 0) are shown in Table 12.10 in addition to these data, the submission dossier should contain the test reports plus chemical specification, intended use, immediate and longer term marketing volumes, a declaration concerning any unfavourable effects of the substance, proposed classification and labelling, and recommended precautions for its safe use. The exact test requirements for Level 1 will be subject to the results of Level 0 and exposure patterns to man and the environment. 

COP22 Dangerous substances Classification and labelling of substances dangerous for supply. 

C L (Classification and Labelling), Risk and Safety Phrases, Danger and so on lUCLID (International Uniform ChemicaL Information Database) Chemical Data Sheets, lUCLID Export Files, OECD-IUCLID Export Files, FUSES Export Files... 

This step contains an initial evaluation of possible risk to workers due to the toxicity of the plant-protection product. The evaluation is based on the classification and labeling requirements established within the European Community. In order to address the specific need to safeguard the health of workers during re-entry to treated crops, the general safety advice (S-phrases) has to be specified in detail. Delineation of specific instructions for workers regarding classification and labeling is provided below. If no classification or... 

If the classification and labeling of the product according to Tier II indicate that body protection is necessary, the following specific instructions, points 2 and 3, should be included on the label, unless the risk assessment according to Tiers III through V indicates otherwise. Point 2 ... 

Results are adequate for classification and labeling and for risk assessment. 

The third criterion is that the model should target an endpoint relevant for REACH. Only models that address the endpoints of interest for REACH are appropriate within this purpose. We notice that REACH mentions different purposes for the QSAR models classification and labeling, is one possible target of the model, and risk assessment in another. In the first case models are classifiers in the second case a regression more is more suitable. Indeed, in the first case the... 

The United Nations Globally Harmonized System of Classification and Labelling of Chemicals (GHS) includes an internationally standardized guidance procedure on Transformation/Dissolution Protocol (T/DP) for metals and sparingly soluble metal compounds (United Nations, 2007), recently validated by the OECD (Organization for Economic Cooperation and Development). To establish the acute aquatic hazard classification level of a metal-bearing substance under the GHS, data from the T/DP are compared with an acute ecotoxicity reference value (ERV) derived under conditions similar to those of the T/DP. 

United Nations. 2007. Globally Harmonized System of Classification and Labelling of Chemicals, ST/SG/AC. 10/30/Rev.2. 

There is an EU scheme for classification and labelling of dangerous preparations (i.e., formulations of substances) the Dangerous Preparations Directive (DPD) (a. 7). The EU supplier has to keep a record of the evaluation for inspection by the regulatory authorities. There is no obligation to conduct new studies, but the available information has to be used and interpreted according to the DSD and DPD. 

The Global Harmonised Scheme for Classification and Labelling of Chemicals... 

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