Chlorogenic add

Lafay, S., Morand, C., Manach, C., Besson, C., Scalbert, A. (2006). Absorption and metabolism of caffeic acid and chlorogenic add in the small intestine of rats. British J. Nutr., 96, 39-46. 

Reference substances Rutoside Echinacoside, cynarine, cichoric + chlorogenic add... 

Lane 1 reference substances with ascending hRf values rutoside, chlorogenic add, hyperoside, lane 2 early golden rod herb DE, lane 3 horsetail herb DE, lane 4 birch leaves DE, lane 5 hawthorn leaves and flowers DE... 

Stramonii folium (7) is characterized by five orange fluore.scent quercetin glycosides in the R, range 0.03-0,25. The absence of rutin and chlorogenic add clearly distinguishes the drug from Belladonnae and Hyoscyami folium. Hyoscyami mutici folium (9] has only a very low flavonoid content. 

The caffeic acid derivatives with chlorogenic add at R, 0.45 (Tl) and isochlorogenic acids at RfO. 7-0.8 are more concentrated in Abrotani herba (1) than in Fabiani herba (2). The later shows rutin at Rf — 0.4 as a prominent orange zone and tlie violet-blue Zone of scopoletin-7-O-primveroside at Rf 0.15. Blue coumarin and orange fluorescent flavonoid aglycones move with the solvent front,... 

The Tiliae flos samples 6-10 show quantitative differences in their flavonoid content, depending on the corresponding Tilia species (T, cordata, T. platyphyllo.s or a mixture of both). The main zones in all samples are in the Rf range of liyperoside (Tl). Blue and orange zones in the R, range of chlorogenic add (Tl) can be absent. 

The dried herbs of some Artemisia species have been used for the treatment of inflammation, blood diseases caused by the disturbance of menses, haematemesis, haematuria, hemorrhoids and diarrhea in Chinese, Korean and Japanese traditional medicine. In Japan, A. princeps and A. montana are the main species used for these purposes. Chlorogenic add, methyl chlorogenate, 3,5-di-O-caffeoylquinic acid, 4,5-di-O-caffeoylquinic acid and 3,4-di-O-caffeoylquinic add were isolated from the leaf of A. montana, and these compounds can be called "caffeetannins" "Fig. (31)". We found that these caffeetannins inhibited the ADP plus NADPH-induced lipid peroxidation in rat liver microsomes. [17] Furthermore, as shown in "Table (12) and Table (13)", the acetone extracts of A. montana reduced the elevations of LPO, GOT and GOT in the serum of rats fed peroxidized oil for 7 days. Caffeic acid and chlorogenic add also inhibited the elevation of serum TG, LPO, TC, GOT and GPT "Table (14) and Table (15)". 

Table 15. Effects of caffeic add and chlorogenic add on serum transaminases (GOT and GPT) in rats fed peroxidized corn oil for 1 week...

The predominant organic adds in commonly consumed fruit are citric and/or malic acids. Actinidia fruits are unusual in that quinic acid levels are similar to that of citric add as the predominant organic add. Although the nutritional importance of quinic add has not been established, it is an intensely interesting compound because it is a key intermediate for aromatic compound biosynthesis via the shikimic add pathway. Moreover, quinic add is a component of several potent free radical scavengers, including chlorogenic add. 

Caffeoylquinic acid (chlorogenic add) 4-0-Caffeoylquinic acid (cryptochlorogenic acid) 3-0-Caffeoylquinic acid (neochlorogenic acid) Isorhamnetin rutinoside Isorhamnetin glucoside Kaempferol rutinoside Kaempferol glucoside... 

Bouayed J, Rammal H, Dicko A, Younos C, Soulimani R. (2007). Chlorogenic add, a polyphenol from Prunus domestica (Mirabelle), with coupled anxiolytic and antioxidant effects. Journal of the Neurological Sdences, Vol. 262, p>p. 77-84... 

Chlorogenic add, feruhc acid, vanillic add, caffeic acid, catechol in coffee extracts... 

Figure 3 Conversion volume of tyrosine residues in different substrates (Tyr- tyrosine, Wh - wool hydrolysate, CA- caffdc add, CHG - chlorogenic add) to DOPA depending on the incubation time. 

Kojima M, Kondo J (1985) An enzyme in sweet potato root which catalyzes the conversion of chlorogenic add, 3-caffeoylquinic add, to isochlorogenic acid, 3,5-dicaffeoylquinic acid. Agric Biol Chem 49 2467-2469... 

Politis J (1948) Distribution of chlorogenic add in Solanaceae and in the organs of these plants. Compt Rend 226 692-693... 

Booth AN, Emerson OH, Jones IT, Deeds F. Urinary metabolites of caffeic and chlorogenic adds. J Biol Chem 1957 229 51-59. 

Main components 5-caffeoylquinic acid (chlorogenic add Arabica 3.0-5.6% Robusta 4.4-6.6%). 

The main substrates of polyphenol oxidases in apples are hydrox-ycinnamic acid derivatives, especially caffeic add depsides, such as chlorogenic acid, and some groups of flavonoid compounds, such as flavan-3-ols, flavonols, dihydrochalcones and (in red-skinned apple varieties) also anthocyanins. In the flesh of apples, the main phenohcs are chlorogenic (3-caffeoylquinic) add, flavan-3-ol epicatechm, and procyanidin B2 representing condensed tannins. These three compounds represent more than 90% of the phenolic compounds present. The main substrates in apple peel are flavan-3-ols and flavonols (quercetin glycosides) and to a lesser extent derivatives of hydroxydnnamic acids are present (chlorogenic add and some other depsides). 

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