Stramonii folium

STRAMONIUM LEAF, Stramonii folium is the dried leaf of Datura stramonium X., family Solanaceae, with violet flowers and spiny capsule. Originally from Central America it is now spread globally in warm regions. The alkaloid content is 0.2-0.6%, with L-hyoscyamine and L-scopolamine found in the ratio 2 1 in mature plants. 

This is the preferred method for leaf drugs e.g. Relladonnae folium (0.6g), Stramonii folium (0.4g), Hyoscyami folium (2g) or Fumariae herba (1 g). 

For Stramonii folium (T3) 4.2ml scopolamine hydrobromide solution is added to 3.8ml hyoscyamine sulphate solution 20pi is used for TLC. 

Alkaloid extract 1 Belladonnae folium 2 Hyoscyami folium 3 Stramonii folium... 

Belladonnae radix 7 Stramonii folium 9 Hyoscyami mutici folium... 

Alkaloids in Belladonnae, Hyoscyami and Stramonii folium (1-3). The tropane alka-loid.s (-)-hyoscyamine (during extraction procedures partly changed into ( ) atropine) and scopolamine as major compounds of the aUcaloidal fraction of Solanaceae drugs respond to Dragendorff reagent with orange, unstable colour. Treatment with NaNO, increa.ses the colour stability of the hyoscyamine zones. 

Stramonii folium (3) a higher scopolamine content than in (1) and (2). The typical hyoscyamine to scopolamine ratio for this drug is about 2 1,... 

Stramonii folium (7) is characterized by five orange fluore.scent quercetin glycosides in the R, range 0.03-0,25. The absence of rutin and chlorogenic add clearly distinguishes the drug from Belladonnae and Hyoscyami folium. Hyoscyami mutici folium (9] has only a very low flavonoid content. 

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