Chemical Industry Institute Toxicology

Based on tests with laboratory animals, aniline may cause cancer. The National Cancer Institute (NCI) and the Chemical Industry Institute of Toxicology (CUT) conducted lifetime rodent feeding studies, and both studies found tumors of the spleen at high dosage (100 —300 mg/kg pet day of aniline chloride). CUT found no tumors at the 10—30 mg/kg per day feeding rates. The latter value is equivalent to a human 8-h inhalation level of 17—50 ppm aniline vapor. In a short term (10-d) inhalation toxicity test by Du Pont, a no-effect level of 17 ppm aniline vapor was found for rats. At high levels (47—87 ppm), there were blood-related effects which were largely reversible within a 13-d recovery period (70). 

Chemical Company of Malaysia Berhad, See CCM Chemicals Sdn Bird (Malaysia), 191 Chemical Databases Software, 308 Chemical Fabrics and Film Association, 269 Chemical Industries Association (CIA), 265 Chemical Industry Institute of Toxicology (CUT), 269 Chemical Institute of Canada (CIC), 259 Chemical Lime Co., 223... 

CIIT. 1983a. 90-Day vapor inhalation toxicity study of hydrogen sulfide in B6C3Fj mice. Report to the Chemical Industry Institute of Toxicology, Research Triangle Park, NC, by ToxiGenics, Inc. CUT docket 42063. 

BP = British Petroleum America CUT = Chemical Industry Institute of Toxicology NCI = National Cancer Institute NIEHS = National Institute of Environmental Health Sciences NIOSH =... 

CUT. 1977. Current status report No. 1. -Hexane. Chemical Industry Institute of Toxicology,... 

External Activities. The chemical industry responds to TSCA through a variety of activities external to the individual corporation or company. Such organizations did not arise as a result directly of TSCA but do respond to some of TSCA s requirements. For example, the CUT (Chemical Industry Institute of Toxicology) carries on testing of various chemical substances for the chemical industry, thus preventing duplicative testing by each manufacturer or user. In addition, its separate identity from the chemical industry increases the acceptability of its test results. 

McNulty MJ Biochemical Toxicology of Inhaled Dimethylamine, pp 1-4. CUT Activities. Chemical Industry Institute of Toxicology August 1983... 

J.A. Bond, Department of Biochemical Toxicology, Chemical Industry Institute of Toxicology, PO Box 12137, 6 Davis Drive, Research Triangle Park, NC 27709, United States... 

Butterworth BE. 1984. The genetic toxicology of di(2-cthylhexyl)phthalate. Chemical Industry Institute of Toxicology (CUT) 4 1-8. 

Heck HD, Casanova M, McNulty MJ, et al. 1984. Mechanisms of nasal toxicity induced by formaldehyde and acrolein. In Barrow CS, ed. 7th Conference on Toxicology Chemical Industry Institute of Toxicology Series Toxicology of the Nasal Passages, Raleigh, NC, Feb. 22-23, 1984. New York, NY Hemisphere Publishing Corp., 235-248. 

US,NATIONAL CENTER FOR ENVIRONMENTAL HEALTH CHEMICAL INDUSTRY INSTITUTE OF TOXICOLOGY... 

Karns, W. D. "Long-Tern Inhalation Toxicity and Carcinogenicity Studies of formaldehyde in Rats and Mice." The Third Chemical Industry Institute of Toxicology Conference on Toxicology, Raleigh, NC, 1980. 

Chemicals Inspection and Testing Institute Japan (1992) Data of existing chemicals based on the CSCL Japan. Japan Chemicals Industry Ecology-Toxicology 8c Information Center... 

Robert A. Neal, Chemical Industry Institute of Toxicology, Research Triangle Park, North Carolina Ian Nlsbet, Clement Associates, Inc., Arlington, Virginia John Peters, University of Southern California School of Medicine, Los Angeles, California... 

Loury DJ, Butterworth BE. 1986. Kidney-specific DNA repair assay An evaluation of unleaded gasoline. Chemical Industry Institute of Toxicology 6 1-8. 

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