Vapor inhalation toxicity

Polymers. Studies to determine possible exposure of workers to residual epichl orohydrin and ethylene oxide monomers in the polymers have been done. Tests of warehouse air where Hydrin H and Hydrin C are stored showed epichl orohydrin levels below 0.5 ppm. Air samples taken above laboratory mixing equipment (Banbury mixer and 6" x 12" mill) when compounds of Hydrin H or C were mixed gave epichl orohydrin levels below detectable limits, and ethylene oxide levels less than 0.2 ppm, well below permissible exposure limits (46). A subacute vapor inhalation toxicity study in which animals were exposed to emission products from compounded Parel 58 suggests that no significant health effects would be expected in workers periodically exposed to these vapors (47). 

CIIT. 1983a. 90-Day vapor inhalation toxicity study of hydrogen sulfide in B6C3Fj mice. Report to the Chemical Industry Institute of Toxicology, Research Triangle Park, NC, by ToxiGenics, Inc. CUT docket 42063. 

Mattie, D.R., et al., A 90-day continuous vapor inhalation toxicity study of JP-8 jet fuel followed by 20 or 21 months of recovery in Fischer 344 rats and C57BL/6 mice, Toxicol. Pathol., 19, 77, 1991. 

Gaworski CL, Haun CC, MacEwen JD, et al A 90-day vapor inhalation toxicity study of decalin. Fundam Appl Toxicol 5 785-793, 1985... 

Phillips RD, Moran EJ, Dodd DE, et al A 14-week vapor inhalation toxicity study of methyl isobutyl ketone. Eundam Appl Toxicol 9 380-388, 1987... 

Industrial Biotest Laboratory. 1978. 90-Day subacute vapor inhalation toxicity study with monochlorobenzene, lot no. 616 in beagle dogs and albino rats. Report to Monsanto Chemical Company, St. Louis, MO. 

IBT. 1975. Acute vapor inhalation toxicity study with dibutyltin dichloride in rats. Report to M and T Chemicals, Inc., Rahway, NJ, by Industrial Bio-Test Laboratories, Inc., Northbrook, IL. IBT No. 66307183. 

Nachreiner DJ. 1994. Etliylene glycol butyl ether Acute vapor inhalation toxicity study in guinea pigs. Bushy Run Research Center, Union Carbide Corporation. Sponsored by Chemical Manufacturers Association, Washington, D.C., 94N1392. 

Philhps, R. D., Moran, E. J., Dodd, D. E., Fowler, E. H., Kary, C. D., and O Donoghue, J. (1987). A 14-week vapor inhalation toxicity study of methyl isobutyl ketone. Fundam Appl Toxicol 9, 380-388. 

Bond JA, Medinsky MA, Wolf DC, Dorman DC, Cattley R, Farris G, Wong B, Morgan K, Janszen D, Turner MJ, Simmer SCJ (1996a) Ethyl tertiary butyl ether (ETBE) ninety-day vapor inhalation toxicity study with neurotoxicity evaluations in Fischer 344 rats. CUT Project ID 95029, unpublished study for ARCO Chemical Company, PA, USA... 

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