Change analysis report

The change analysis report provides formal documentation and feedback of safety analyses performed on changes to the end product throughout the life cycle. 

A change analysis report is prepared at any time during the life cycle when a change is made to a design, drawing, component, subsystem, or any other part of the project after the safety analysis of that particular part of the project is complete. 

The change analysis report is normally prepared by the system safety working group. 

Instructions for preparing a change analysis report are included in Chapter... 

When should a change analysis report be prepared ... 

Customer complaints Warranty claims Failure analysis reports Process capability studies Service reports Concessions Change requests Subcontractor assessments Performance analysis Deviations and waivers Contract change records Quality cost data External Quality Audit records... 

The XRD data and Zn/Cu ratio are also given for a reference aurlchalclte specimen reported In the literature ( ). All d-spaclngs In the mineral and synthetic aurlchalclte matched the literature values within the lattice volume changes (<2%) reported In Table 1. Over 30 XRD peaks were used In the XRD comparisons. The XRD analysis established that the structure of the mineral and synthetic aurlchalclte was essentially Identical. The only distinguishing features were the higher Cu content and the 1.6Z smaller unit cell volume of the mineral sample compared to the synthetic sample. 

Adenosine triphosphate is utilized in portions of the cell other than the mitochondria and chloroplasts therefore, the utilization as well as the production of ATP is of importance to total adenylate status. As a result, it became important to consider total ATP content of plants. When detached pinto bean leaves were exposed to 1,0 yl/1 ozone for 30 min total ATP content of the leaf decreased (12), Since ozone altered leaf ATP content it could also alter the leaf s adenylate status we wished to determine if a correlation existed between alteration in adenylates and the change previously reported in photosynthesis and respiration. Since ATP is readily broken down by adenosine triphosphatases, a reliable method of extraction and quantitative method of ATP analysis was designed for the study (8),... 

In a meta-analysis of the metabolic and psychosocial impact of pumps, 52 studies were found 22 were published before 1987 and 13 after 1993, the year in which the results of the DCCT were published (225). The authors stated that therefore conclusions about efficacy are not definitive. All pump malfunctions were reported before 1988. All types of changes were reported when the frequency and severity of hypoglycemia were compared with prepump times. Infection and skin irritation were expressed in different ways in the various studies. The risk of diabetic ketoacidosis fell after 1993. Most users preferred to continue pump treatment, mainly because of more flexibility, greater freedom, and improved glycemic control. 

As part of the semi-quantitative risk analysis report to corporate, the analysis team included an evaluation of the recommended risk mitigation options. For chlorine, the second recommendation was not practical because the end user required ton containers thus, the transport of smaller cylinders was not an option for the customer. Therefore, this recommendation was removed from further consideration. Since ton containers are shipped via truck, an alternate route was discussed with the carrier—a new route that eliminated passing near higher-population densities with little change in the distance or conditions of the route. 

DOE O 5480.23 Nuclear Safety Analysis Reports For nuclear facilities only (Hazard Category 3 or above), requires preliminary and final hazard categorization and comprehensive hazard/safety analysis to support the conclusion that nuclear facility activities can be conducted without causing unacceptable health or safety impacts to workers, public, or environment. SAR prepared in accordance with DOE-STD-3009 or a BIO prepared in accordance with DOE-STD-3011. Annual updates to either SAR or BIO for those changes that affect the safety basis. Preliminary and final hazard categorization prepared in accordance with DOE-STD-1027. 

When the results of MS I for a plant item that is out of service fall outside the acceptance criteria, then that plant item, unless it is repaired, replaced or modified, should remain non-operational until the safety aspects have been reviewed. If a review of the safety aspects for such a safety related plant itan shows that its reliability and effectiveness have been affected, and if it is confirmed that a decision was taken not to repair, replace or modify it, then the deviation from the acceptance criteria should be justified in accordance with established procedures as a change to the safety analysis report. Any such plant item should remain non-operational until a justification of the deviation has been completed and approval of the regulatory body, if required, has been obtained. If the results of MS I or of the review show that other SSCs of the plant may have similar defects, these SSCs should be inspected as soon as possible. 

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