Cell Cytokines

Geng YJ, Holm J, Nygren S, Bruzelius M, Stemme S, Hansson GK. Expression of the macrophage scavenger receptor in atheroma—relationship to immune activation and the T-cell cytokine interferon-gamma. Arterioscler Thromb Vase Biol 1995 15(11) 1995-2002. 

Murdoch C, Monk PN, Finn A. CXC chemokine receptor expression on human endothelial cells. Cytokine 1999 11(9) 704—712. 

T Helper Cell Cytokine Responses During Intestinal Nematode Infection Induction, Regulation and Effector Function... 

Karpus, W.J., Lukas, N.W., Kennedy, K.J., Smith, W.S., Hurst, S.D. and Barrett, T.A. (1997) Differential C-C chemokine-induced enhancement of T helper cell cytokine production. Journal of Immunology 158, 4129-4136. 

Subramanian, G., Kazura, J.W., Pearlman, E., Jia, X., Malhorta, I. and King, C.L. (1997) B7-2 requirement for helminth induced granuloma formation and CD4 type 2 T helper cell cytokine expression. Journal of Immunology 158, 5914-5920. 

Ramegowda B, Samuel JE, Tesh VL Interaction of Shiga toxins with human brain micro-vascular endothelial cells Cytokines as sensitizing agents. J Infect Dis 1999 180 1205— 1213. 

Theophylline appears to produce bronchodilation by inhibiting phosphodiesterases, which may also result in antiinflammatory and other nonbronchodilator activity through decreased mast cell mediator release, decreased eosinophil basic protein release, decreased T-lymphocyte proliferation, decreased T-cell cytokine release, and decreased plasma exudation. 

Heymann D, Rousselle AV (2000) gpl30 Cytokine family and bone cells. Cytokine 12 1455-1468... 

Chipeta, J., et al. CD4+ and CD8+ cell cytokine profiles in neonates, older children, and adults increasing T helper type 1 and T cytotoxic type 1 cell populations with age, Cell. Immunol., 183, 149, 1998. 

Ramer-Quinn, D.S., Baker, R.A., and Sanders, V.M., Activated T helper 1 and T helper 2 cells differentially express the P-2-adrenergic receptor A mechanism for selective modulation of T helper 1 cell cytokine production, J. Immunol., 159, 4857,1997. 

Stress-related immune dysregulation also involves the synthesis of hormones including ACTH, growth hormone, and prolactin.14-17 Interestingly, it has also been demonstrated that various aspects of the immune response, for example., proliferation of B- and T-cells, cytokine production, antibody production, chemotaxis of monocytes and neutrophils, and natural killer (NK) cell cytotoxicity, can be affected by glucocorticoids (including cortisol) as well as peptides such as ACTH, CRH, endorphins, substance P, and somatostatin.1218... 

Manetz, T.C., Pettit, D.A. and Meade, B.J., The determination of draining lymph node cell cytokine mRNA levels in BALB/c mice following dermal sodium lauryl sulfate, di-nitrofluorobenzene, and toluene diisocyanate exposure. Toxicol. Appl. Pharm., 171, 174, 2001. 

Th2 cells selectively express IL-21 in addition to the classic Th2 cytokines IL-4, IL-5, and IL-13. In contrast to these clustered Th2 cell cytokine genes, the IL-21 gene resides on a different... 

Bullens DM Measuring T-cell cytokines in allergic upper and lower airway inflammation can we move to the clinic Inflamm Allergy Drug Targets 2007 6 81-90. 

Bucy, R.P., Panoskaltsis-Mortari, A., Huang, G., et al. (1994) Heterogenicity of single cell cytokine gene expression in clonal T cell populations. J. Exp. Med. 180, 1251-1262. 

NT062 Petro, T. M., and S. Zhang. The effect of smokeless tobacco extract on murine T cell cytokine production. Immune-pharmacology 1997 36(1) 17-26. 

Anticancer intCTleukin-2/T-cell cytokine protein (growth factor)... 

C. T Cell Cytokine Production in Presence and Absence of N°-Monomethyl-L-Arginine... 

Hernandez, H.J., Sharpe, A.H. and Stadecker, M.J. (1999) Experimental murine schistosomiasis in the absence of B7 costimulatory molecules reversal of elicited T cell cytokine profile and partial inhibition of egg granuloma formation. The Journal of Immunology 1 62, 2884-2889. 

In contrast to animal models, the immunologic response to sublingual immunotherapy (SLIT) in humans has been difficult to demonstrate. Specific IgE suppression, specific IgG production or changes in the T cell-cytokine profile seem to be little affected by SLIT [9-13]. 

Pan et al., 2005). Regardless of the specific mechanism involved, the dn-CaMKIV and Camk4 1 mouse models together with the human naive T cell results clearly show that CaMKIV is required to activate T cell cytokine synthesis in response to TCR stimulation. The point at which CaMKIV acts in the different types of T cells is summarized in Figure 4. 

Meningococcal disease (MCD) is the commonest infective cause of death in children in Western societies. In MCD and all forms of sepsis, there is a complex interaction among cytokines and a wide variety of immune-system and non-immune-system cells. Cytokines that have been shown to be involved in the pathogenesis of MCD include proinflammatory cytokines, TNF-o, IL-1/3, IL-2, IL-6, IL-12, LIF, and IL-18 interferons, IFN-y, IFN-a chemokines, IL-8, RANTES, MIP-1 a,ft, MCP-1, GRO-a and colony-stimulating factors, G-CSF, GM-CSF, and M-CSF (HI). 

The direct effects opioid and opioidlike peptides exhibit on cells of the immune system is both varied and, in some instances, contradictory, depending on which receptor subtype is being studied. Mu and kappa receptors generally affect immunofunction in a suppressive manner, where delta receptors tend to express immunostimulation [82-85]. However, selected delta antagonists have shown to elicit suppressive effects on B-cell proliferation, NK cell activity, and T-helper cell cytokine production [86]. The alteration of leukocyte function via opioid receptors will be discussed highlighting specific cell subtype immunomodulation. Endorphin shows a inhibitory effect on splenocyte proliferation through central and peripheral autocrine/paracrine pathways [87]. 

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